Phase Genomics

From the ⁦@MicrobiomeTimes⁩ Partnership Forum in Copenhagen with colleagues abound including ⁦@evohologen⁩ ⁦@chuttenh⁩ ⁦@PhaseGenomics⁩ ⁦@MortenLimborg⁩ ⁦@SeventureP⁩. The best of the microbiome science applications is here, Wolbachia included!

32% off ProxiMeta™ Hi-C kits ends 3/15 (then save 16% through end of month). You’ll get: ✅ High-quality MAGs from complex samples ✅ More complete genomes than traditional binning ✅ Accurate host attribution for phages, plasmids, and AMR genes 👉info.phasegenomics.com/march-magness

March MAGness is here! Score special pricing on ProxiMeta™ Hi-C kits for metagenomics & microbiome studies in everything from complex soil samples, to gut microbiomes, to bioreactors: 🔬 32% off | March 2–15 🔬 16% off | March 16–31 Get started here 👇 info.phasegenomics.com/march-magness

FISH finds what it's looking for, and only what it's looking for. In a new study in @AjHematologyshows, Hi-C confirmed FISH findings, plus chromothripsis, CN-LOH & complex rearrangements that FISH probes can’t pinpoint. 🔗onlinelibrary.wiley.com/doi/epdf/10.10…

New Nature Plants study using Proximo™ Hi-C shows how a hybrid eelgrass species inherited low-light tolerance genes from its deep-water parent that could change how we approach coastal restoration. More from Todd Michael, PhD & team at @salkinstitute 📄 nature.com/articles/s4147…

New Publication in @PLOSBiology : Optimized Hi-C analysis (Z-score filtering) boosts specificity & reveals virus-host interactions using Phase Genomics’ ProxiMeta™ Hi-C: 79 genus-level matches + 293 new linkages in well-studied, climate-critical soils. journals.plos.org/plosbiology/ar…

"A year and a half ago, we couldn't have resolved this hybrid genome." New tech (long reads + Hi-C) let researchers separate parental haplotypes in eelgrass revealing which genes drive low-light tolerance. Todd Michael (@genomeslab) breaks down how:

Phase Genomics IRL: a few days together in Portland for real-time collab & creativity. Aligning on new products, pressure-testing ideas, a little fun behind the wheel. It’s how we build even better Hi-C tools for the researchers who rely on them. A few of our favorite moments👇

Tissue prep drives variability early in Hi-C workflows. A new STAR Protocol adds cryogenic tissue grinding before crosslinking, with safe pause points for optimized lab workflows. See how it improves reproducibility & library quality ⬇️ star-protocols.cell.com/protocols/4702

Combining @PhaseGenomics and @PacBio HiFi allowed acquisition of the complete 🦠genome. It is composed of 1 chromosome and 2 plasmids, which are mobilome-rich, encoding prophages, an orphan CRISPR array, and complete pathways for many novel and essential cofactors, including heme

Big congrats to PhD @Ken_M_Mugambi for pulling together this amazing piece of work 🫡 This study details the genome biology of the largest #AMF genome (G. margarita) and its intricate links with its🦠 endosymbiont and 🌱hosts 😀 biorxiv.org/content/10.648…

Wheels up ✈️ Our CEO Ivan’s headed to Newport Beach for Microbes in Wastewater. He’ll show how ProxiMeta™ links microbes, phages & the mobilome to track #AMR in wastewater. No coding. Just discovery. If you’ll be in Newport for the conference, say hi to @IvanLiachko!

We heard you. Our 25 in ’25 promo is extended through Jan 16. Save 25% on Phase Genomics Hi-C kits via direct order, book a complimentary bioinformatics consult, and access discounted full-service ProxiMeta™ packages. Get started → info.phasegenomics.com/25-in-25

Bees carry more than nectar. Their gut microbiomes buzz with plasmids, sharing tetracycline resistance genes across hives. @shy_symbiont from @ChicaScientific’s lab used Hi-C to track these mobile elements & explore colony-specific patterns traditional metagenomics misses.

Stuck on Hi-C data? First 25 researchers to email get a free consult with our computational scientists—whether you're using our kits or another provider's. Email info@phasegenomics.com with "25 in '25 Bioinformatics Promo" in the subject line to claim yours.

Save 25% on Hi-C kits through Dec 31. From complex plant genomes to metagenome binning, Phase Genomics brings clarity to your toughest research questions. Email info@phasegenomics.com with "25 in '25 Kit Promo" in the subject line to claim your discount.

Mobile genetic elements buzz through bee guts. @ChicaScientific’s team at Indiana University used Phase Genomics’ Hi-C to connect plasmids + phages to microbes, showing how bee behaviors drive gene sharing & #AMR. More in the preprint from @shy_symbiont: biorxiv.org/content/10.110…

Discover how the research team used our Proximo™ Hi-C plant kit in the full paper: academic.oup.com/jhered/advance…

🌿 Scientists have produced a high-quality, chromosome-scale genome for American pickleweed, a salt-loving, tetraploid marsh plant. With ~80k genes and detailed methylation data, this resource paves the way for understanding salt-tolerance and supporting salt-marsh conservation.

New at #AMPath2025: He Fang, PhD, will showcase Genomic Proximity Mapping® (GPM) and CytoTerra® in #sarcoma. Stop by Level 2, 258ABC on 11/13 from 2:30 – 3:30 pm ET to discover how GPM uncovers hidden structural variants and mosaicism in challenging archival samples.