Philip Bejon

Congratulations to @wellcometrust sponsored Rinter Kimathi on a successful viva today. We produce quality #PhD students here 🥇 📜 @UofGlasgow @Paulgarside6 @scales_hannah @Fra_ndu @AndrewPWaters @BiottofnI @cowan_lab

We @KEMRI_Wellcome are thrilled to celebrate the renewal of our collaboration between @wellcometrust, @KEMRI_Kenya, and @UniofOxford and look forward to continuing to advance our mission to advance purposeful and impactful health research, and developing research capacity in the African region. We are super grateful to the @wellcometrust for committing to fund this collaboration with a GBP 90 million core award

Delighted to announce the renewal of the collaboration between @wellcometrust @KEMRI_Kenya and @UniofOxford with the signing of the 7-year Memorandum of Agreement. This is in support of discovery and mental health research, climate and health and the evaluation of Kenya's Universal Health coverage initiative at #KWTRP

Congratulations to our Fellows. You all look great!

Congratulations to the Postgraduate Diploma #ClassOf2024 graduates from @PU_Kilifi! We are proud of your success. A big thank you to the exceptional supervisors at @KEMRI_Wellcome and our funding partners @SciforAfrica for making this journey possible.

Newly minted! DOCTOR PATRICK MWANGALA! CONGRATULATIONS! And to your supervisory team lead by Prof Amina Abubakar and Prof Charles Newton. Collaboration between IDeAL and ALMA growing strong @akuihd @KEMRI_Wellcome @IDeAL_KEMRI_WT

Compensatory evolution after evolving resistance well documented for bacteria and for malaria parasites - and I'm sure other instances - here described for candida auris as well.

The Sanger PrizeThe Sanger Prize - The Sanger Prize is an outreach competition aimed at undergraduate students who live and study in low or middle income countries sanger.ac.uk/about/study/th… #sangerinstitute

Research Highlight from Anthony Etyang @TonyEtyang @KEMRI_Wellcome Prospective clinical surveillance for severe acute respiratory illness and COVID-19 vaccine effectiveness in Kenyan hospitals during the COVID-19 pandemic ndm.ac/tropmed.res-hi bmcinfectdis.biomedcentral.com/articles/10.11…

The top three pathogens, E. coli (24%), K. pneumoniae (8.7%) and S. aureus (8.5%) exhibited increasing prevalence and multidrug #resistance💊 Enhanced surveillance and antimicrobial stewardship are crucial for managing BSIs in Vietnam🇻🇳 (5/5)

Research published last month in @npjAMR describes bloodstream infections within a Vietnamese infectious diseases hospital between 2010 and 2020 🇻🇳🦠 Check out this article in the link below!⤵️ @DuyPham_Oucru (1/5) nature.com/articles/s4425…

READING TIP: Rethinking the Evidence on COVID in Africa - africarxiv.ubuntunet.net/handle/1/1671 To submit your research & to learn more about our work, please visit africarxiv.org #ResearchinAfrica #OpenScience #OpenAccess @PhilipBejon @AmbroseAgweyu @isabellaoyier @EdwineBarasa

@gushamilton Thanks, very helpful. RCT was a lower risk group (for obvious reasons). Looked at Kumar et al and agree looks staggering to get ORs of 92 by end. Agree overstatement, propensity score adjustments would help, but "know it's wrong" also seems overstatement to me.

@PhilipBejon I'm not saying giving earlier antibiotics is bad (clearly not!) but we cannot honestly state the effect size is 8% per hour, it's an implausibly large effect from a design highly susceptible to bias. RCTs of early antibiotics are null, so the effect size is likely much smaller.

WILL PEOPLE PLEASE STOP CITING KUMAR ET AL CRIT CARE MEDICINE 2006 AND CLAIMING a 7.6% MORTALITY DECREASE PER HOUR WITH ANTIBIOTICS. THIS IS COMPLETELY NOT TRUE AND HAS BEEN KNOWN FOR YEARS! god this zombie fact WILL NOT die. There are RCT's on the topic!! No effect!!

@gushamilton Interested in hearing more - how do we know it is false?

do the authors genuinely not know this or do they cite it to strengthen their argument knowing it is false? We don't need to over-emphasise the benefits of IVD for infection, its clearly important, but don't cite things that are clearly not true!