PlesaLab

New lab preprint: if ML struggles with extrapolation, let's expand the diversity of training data with gene synth, DNA shuffling, and ML gen.... also lots of #FluorescentProteins #ProteinEngineering #MachineLearning #SyntheticBiology 1/n

Need long-read sequencing? We’ve just completed the first ever run on @uoregon GC3F core’s new @PacBio Revio instrument! Perfect for amplicons too long for Illumina, and with Kinnex prep, you can get >10x more data. Great pricing, no queue, try it out. gc3f.uoregon.edu/pacbio-sequenc…

Lab memes!

Congratulations @TrieneToScience for winning the people’s choice award at the Oregon Bio Innovation Showcase today!!

Interested in antibody generation and expression of human proteins in bacteria? If you're at @ProteinSociety tonight check out poster 75 at Bayshore Grand Ballroom D with @MuggleInSynbio to hear about expressing the human proteome in E. coli. @UOKnightCampus

Powerful 1st-person piece by Knight Campus Dept of Bioengineering Asst Prof Parisa Hosseinzadeh on her long road to recovery following a brain hemorrhage in Nov. 2022. We are so inspired by your strength & determination Parisa and are happy to see you growing stronger every day

At @ProteinSociety tonight check out poster 73 with @AlkynesOfSci to hear about our efforts to deorphanize sensor histidine kinases en masse & poster 117 with @TrieneToScience to hear about BAR-CAT, our approach to scalable enrichment of assembled gene libraries. @UOKnightCampus

Christmas came early in @PlesaLab with the latest Degenerate DropSynth preprint and the fun was doubled up by lovely Secret Santas in the lab and the Impact & Innovation Award in the annual celebration at @UOKnightCampus 🎉🎁 Signing off 2023 slowly with style 😎

Story time! Introducing the first of several new flavors of DropSynth #genesynthesis we have been working on, cooked up by @AlkynesOfSci and Sam Hinton. TLDR: We show multiple gene variants assembled per barcoded droplet and 1 kbp lengths. 1/n biorxiv.org/content/10.110…

The Department of Bioengineering Seminar Series continued today with Biochemistry PhD student Andrew Holston (Plesa Lab) and #KnightCampusBioe PhD student Sam Lester (Guldberg Lab) who gave talks in the Beetham Seminar Room. The seminar series is held most Mondays.

Roughly half the world's population is infected with H. pylori, a leading cause of stomach cancer. A group of UO undergraduates are working on a probiotic they hope could be a gamechanger. The iGEM team is raising funds to take their project to Paris: brnw.ch/21wCypS

Carmen, Yuki, and I representing @PlesaLab from @UOKnightCampus at #VariantEffect23 ! It's been a pleasure to see the amazing research and to share our work.

@PlesaLab is full of cool surprises!

When you hit the desk on a weekend to spot an art by the #LOTR geek, and instantly know it’s none other than your PI ! @PlesaLab How many of you have items named in the lab? #research #sciencetwitter #academiclife

A perfect getaway for a lab retreat on a sunny weekend. More to follow soon! @PlesaLab @sweetcheekswine

End of the year celebration in @UOKnightCampus and what a blast ❤️❤️❤️

A perfect 20.000 score on the Nanophotometer Attracts attention, but watch those ratios, or else you'll be a goner! Stay focused, don't let your measurements falter. 9/n

Forgotten buffers have been colonized, By herds of wooly mammoths, a surprise, oh my goodness gracious! It's a sight to behold, these majestic creatures on the scene, In the forgotten buffers, they now reign supreme. 8/n

Just in time for Winter a quick tour of the more unusual things around our lab... 1/n