PolarityBio

Quick poll for the wound care community: Which phase of wound healing do most chronic wounds get stuck in? We'll share the answer (and why it matters) in next week's Polarity Perspective blog.

Our Pres. & CMO Dr. Ned Swanson and CSO & COO Nikolai Sopko, MD, PhD, will be at #SAWCSpring2026 to discuss regenerative approaches for chronic wounds and DFUs, including insights from the Phase III COVER DFUS II trial. 📍 Charlotte, NC | 📅 April 8–12 | connect@polaritybio.com

Heading to #SAWCSpring2026? Let’s connect: connect@polaritybio.com Our team will be onsite to discuss evolving regenerative approaches for chronic wounds and diabetic foot ulcers, including insights from the Phase III COVER DFUS II trial. 📅 April 8–12 | 📍 Charlotte, NC

Why does precise language matter? Regenerative should be a biologically grounded concept, tied to how a therapy interacts with the body’s natural healing. Learn more as new biological approaches emerge and why understanding these terms matters: polaritybio.com/polarity-blog/…

In wound care, focus is shifting from “Did it close?” to “How did it heal?” Regenerative therapies span a broad spectrum, and understanding living cells, tissue architecture, and functional restoration is shaping advanced care. More from PolarityBio: polaritybio.com/polarity-blog/…

New podcast with our COO/CSO Nikolai Sopko, MD, PhD, discusses how autologous multicellular skin therapy is designed to support the body’s own healing and is being studied in clinical trials. SkinTE is available for investigational use only. Tune in: podcasthealth.com/podcast/ep-127…

Our COO & CSO Nikolai Sopko joins Better Biopharma to discuss SkinTE, autologous multicellular skin therapy for diabetic foot ulcers, and parallel processing for scalable manufacturing. SkinTE is available for investigational use only. Watch: bit.ly/3PvWMH0

For patients with chronic wounds, the failure is often deeper than what is visible on the surface. Healing requires coordination across dozens of cell types and multiple skin layers. Restoring these systems can improve long-term outcomes and reduce recurrence. In his latest Polarity Perspectives blog, Nikolai Sopko, MD, PhD @urodrnik examines the skin’s regenerative potential and the implications for advanced wound care therapies.

Our latest blog explores what this means for modern wound care: polaritybio.com/polarity-blog/…

Thanks to all who participated in our poll. So, how long does epidermal renewal take? About 28 - 40 days in healthy adults. In chronic wounds, disruption across cellular signaling, vascular function, and immune regulation can impair coordinated regeneration and long-term healing.

Wound care community, weigh in. 👇How often does the skin completely renew the epidermis? We'll share the Polarity Perspective in our upcoming blog on Tuesday, 3/24. Stay tuned!

Most AI cos pitch features. Founders want PROOF. Ayush Mishra asks Dr. Ned Swanson from @PolarityBio_, what separates great AI pitches from red flags? AI startups in pharma: You can't miss this! To hear complete conversation, click here, youtu.be/yvPMwJ3rE6E #AIinPharma

Chronic wounds like diabetic foot ulcers remain a major unmet need worldwide. In a new @BioTuesdays interview, PolarityBio’s COO & CSO, Nikolai Sopko, MD, PhD, discusses how autologous regenerative biologics are advancing functional skin repair. Read: bit.ly/4bs2b9i

Real-world patients don’t always fit narrow trial criteria. In a new Clinical Leader interview, PolarityBio’s CMO Ned Swanson and COO Nikolai Sopko discuss broadening eligibility and diversifying sites to reflect everyday wound care. Dive in: bit.ly/46YMViU

Scarring is a sign of repair, not regeneration. Humans replace their skin every 28-40 days, but full-thickness wounds often overwhelm this innate ability. Learn how we can shift the focus back to functional restoration in the latest Polarity Perspectives: bit.ly/4beHn51

Two therapies derived from human tissue can face very different regulatory expectations. Products regulated as 351 biologics must demonstrate safety, purity, and potency through clinical development and a BLA, while 361 HCT/Ps follow a different pathway. bit.ly/49Zr5O6

One consistent theme from hematology to orthopedics is that functional regeneration often depends on living cells and organized repair. Wound care is no exception. Explore PolarityBio’s approach: polaritybio.com

Most skin grafts restore coverage, not function. What autologous options actually regenerate full-thickness skin? The new Polarity Perspectives covers micrografts, cell suspensions, and more. Dive in: bit.ly/4rrvD6d

#DYK? Wound healing can be shaped by cell source, including autologous therapies that use a patient’s own cells. Understanding where cells come from can help guide treatment strategies and recovery. bit.ly/4c5exWQ

Advancing wound care requires precision in defining regeneration, tissue source, and the role of cellular biology. PolarityBio is committed to developing regenerative biologics that align with natural healing pathways. polaritybio.com