ProtiFi LLC

In MAM, the artifact your sample prep introduces can look just like the modification you're measuring. The ProtiFi™ S-Trap™ MAM Kit's near-neutral on-trap digestion cut N388 deamidation on the NIST mAb PENNY peptide by >99% versus a conventional in-solution method.

We're heading to PEGS Boston May 11–15. Find us at Booth 812 to talk MAM workflows, peptide mapping with Tryp-N™, and high-throughput biopharma sample prep on the S-Trap™ Turbo™. Looking forward to the conversations!

Multi-omics should not require choosing between workflow simplicity and analytical depth. In a study with UNC’s Tamir Lab, Si-Trap™ improved proteome depth while preserving broad metabolite coverage from the same sample. Read more below ⬇️ protifi.com/go/66dxjj7lef

MitoCatch shows the promise of targeted mitochondrial transfer for neurodegeneration. ProtiFi S-Traps™ enabled proteomic confirmation of mitochondrial enrichment in treated neurons. Read more here: protifi.com/go/rjdbaa

Multi-omics has advanced quickly. Si-Trap™ brings proteins, metabolites, & lipids into one workflow from one sample. In HuH-7 PFAS testing, it matched S-Trap™ proteomic depth and produced higher signal for 93% of detected metabolites.  Read more: protifi.com/go/l374cuee5

A new mAb peptide-mapping study highlights Tryp-N™ as a mirror protease to trypsin, adding complementary b-ion-rich evidence for PTMs, SAVs, and sequence confirmation. Read more below. protifi.com/go/l32v4m

Access to reproducible sample prep depends on strong scientific support. We’re proud to highlight @mswilbv, ProtiFi’s European distributor. With deep mass spec roots and a practical, researcher-first approach, they help bring ProtiFi workflows to labs across Europe.

Congratulations to Matt at NYTP Solutions for being recognized as Greece Regional Chamber of Commerce 2026 Business Person of the Year! protifi.com/go/tr5rl5x2x

New research points to ProtiFi’s S-Trap™ as a solid-phase solution for membrane proteome LC-MS workflows. In a 7-workflow comparison, S-Trap™ delivered the strongest integral membrane protein recovery among solid-phase methods. Read more: protifi.com/go/szj9fp42

Multi-omics often means multiple prep workflows and added variability. Our new blog explains how Si-Trap™ captures proteins, metabolites, and lipids from the same sample while maintaining proteomics depth and improving metabolite signal. Read more: protifi.com/go/fm9crt8b

ProtiFi is proud to partner with Biosys Technologies as our designated distributor to Japan. Biosys brings exceptional scientific rigor to the omics community, supporting leading labs with our advanced proteomics solutions as we continue Bringing Precision Omics to Life!™

Visit ProtiFi at Booth #21 in St. Louis at US HUPO (Feb 22–25). 🔬 Introducing Si-Trap™ – first-of-its-kind multi-omics workflow. See our posters: P16.25 & P04.14. protifi.com/what-to-expect…

Optimizing your sample prep protocol can improve sensitivity, reproducibility, & throughput from challenging FFPE samples. Learn strategies to accelerate translational proteomics in our article by ProtiFi CEO Dr. John Wilson, PhD. protifi.com/go/ot1mvgk

ProtiFi has partnered with Bioanalytic to bring our sample prep technology to Central Europe! With 25+ years supporting research labs across the region, we’re excited for the scientific progress this collaboration will enable.

Meet Tyler Scherzi, PhD, Laboratory Scientist on ProtiFi’s R&D team. With expertise in allergens research and drug development, he helps drive innovation in our omics lab. We're thrilled to have him shaping the future of our research!

Our latest offering, the S-Trap™ Turbo™, is bringing groundbreaking efficiency to your proteomics sample prep, saving you time and money. Read more about how the S-Trap™ Turbo™ can redefine your proteomics throughput in our latest article: bit.ly/49CO4gq

Protifi.com has a new look! Our new site makes it easier to access high-quality proteomics products, updated protocols, refreshed FAQs, and a streamlined checkout and quote process, enhancing your experience from purchase to data analysis.

ProtiFi is pleased to announce our partnership with omicslink™ as our trusted distributor to South Asia! We look forward to this fruitful partnership and the emergent work this increased access will facilitate for scientists across the globe!

The new year brings new innovations from ProtiFi: The MAM Kit for biological medicines, Si-Trap™ for multi-omics, and chances to connect with us at conferences worldwide. Thanks for an amazing year – here’s to the discoveries that lie ahead in 2026!

Like the kaleidoscope of proteins that make us unique, our loved ones are quintessential to the qualities that make us who we are. We hope this holiday season, you’re celebrating with those dear to you, both near and far. Happy holidays from the ProtiFi team!