Reid Hoffman

Today, I launched Manas AI –– a full stack AI company setting out to shift drug discovery from a decade-long process to one that takes a few years; bringing life-saving treatments to patients faster than ever.

@pitdesi Not very shocked

actually kind of hilarious (& sad!) that the Trump phone has 11 stripes on it (actual flag has 13) It’s just a Chinese Alibaba phone. He said it was “Made in the USA” but now it says “designed with American values in mind.” It cracks me up

The Anthropic announcements are not, in the end, about Claude winning Wall Street. This moment is about the AI industry maturing past the moment where the model alone is the product.

Some people miss the role crypto can play in the AI world. Digital money can help power the agentic economy, and blockchain will help us solve major online trust gaps (between agents and us, and human to human). Thanks to @CoinDesk for hosting!

what if everything goes right

@zGuz @consensus2026 Thanks for having me on!

Highlight of @consensus2026 for me was getting to ask OpenAI investor and LinkedIn founder @reidhoffman if all the market talk of AI being a bubble was overhyped:

@CyborgNomad @beeple @beeple is a fantastic artist, and a better human!

Are we back… or are we back?! You don’t see this every day — Reid Hoffman praising someone from our NFT space. @beeple remains one of the greatest, showing up daily for the last 18 years. Absolute legend! linkedin.com/pulse/69m-sale…

@Kalshi_Crypto Never thought I'd see myself quoted by Kalshi!

JUST IN: Billionaire LinkedIn Founder says crypto becomes critical in an AI world

Reid Hoffman (@reidhoffman), LinkedIn co-founder, said he’s deeper into crypto than ever bc it can power payments for AI agents He also pointed to crypto’s role in proving humanity online, w/ NFTs potentially becoming a key building block for digital identity & will nv sell $BTC

@Inception0071 I just enjoy em dashes.

@reidhoffman Em dashes for a 2 sentence post, cmon.

Just a reminder that we're likely to see more layoffs announced "because" of AI –– it makes companies seem strong and moving forward. It's important not to ignore other factors, including hiring trends 2020-2023, that might be present.

Introducing Altara: the scientific intelligence platform for the physical world. Today @evatuecke and I are excited to announce our $7M seed led by @GreylockVC, joined by @Neo, @BoxGroup, @Liquid2V, and angel investors including @JeffDean and leadership from OpenAI & AMD. We’re already working with early customers in semiconductors, batteries, and advanced materials. More below.

@mapping_ai Great work

Who actually shapes AI policy in the U.S.? We mapped 1,812 entities: 745 people, 918 organizations, 2,925 relationships. Frontier Labs, AI Safety orgs, Think Tanks, Government, VCs, and more. mapping-ai.org

But the slop might be part of the journey. The GPUs and fiber optics enabling today's slop are the same infrastructure that'll power personalized tutors, real-time climate modeling, and drug discovery at software speed. More: reidhoffman.substack.com/p/in-defense-o…

Now look at AI. Critics say we were promised cancer cures and got fake security-cam footage of cats playing violin on the porch. We're at “Peak Pickle.”

Before electrification ushered in a new era for humanity, it gave us slop. Now AI is heading in the same direction. More on why generating slop is the way that technology reaches peak adoption:

If your doctor isn't asking AI for a second opinion, it's borderline malpractice. We shouldn't be stopping those who save lives from using technology that helps them (1) give better care and (2) care for more people.