Richard James

@ECDC_EU data on the incidence of cases, attributable deaths and disability adjusted life years due to MDR bacterial infections in the EU in 2015 ecdc.europa.eu/en/news-events…

@BioMickWatson I nominated Sir Alexander Fleming for the discovery of penicillin

Choosing £50 note to put a scientist on is some kind of dark irony. Think I've held a £50 note once and I'm 43 years old.

[Open access] article reviewing "The evolving response to antibiotic resistance (1945-2018) nature.com/articles/s4159…

Interesting Open access study of MDR Gram-negative bacteria in hospitalized patients with complicated UTI's aricjournal.biomedcentral.com/articles/10.11…

@DanWalkerLab The effect of antibiotics on the microbiome can be dramatic and persist in offspring

AMR Control 2018 published by Global Health Dynamics in association with the World Alliance Against Antibiotic Resistance (WAAAR) is available here resistancecontrol.info/2018-uk-conten…

Science article about arylomycin derivatives engineered at Genetech that are active against a range of Gram negative pathogens in mice sciencemag.org/news/2018/09/s…

@ABpreservation @SouthAfricanASP You can join the event live or watch the webcast at pewtrusts.org/about/events/2…

@SouthAfricanASP Interesting wish we could gain access to what be said 🤨

Interesting review concludes that maintaining a complex gut microbiota that fills up metabolic niches, resists pathogen colonization and boosts immune defenses has now become a crucial part of our efforts to fight against infectious diseases. ncbi.nlm.nih.gov/pubmed/30205357

FDA Unveils Plan to Combat Antibiotic Resistance by supporting antibiotic innovation and ensure that antimicrobial drugs are used according to good stewardship practices at a live event tomorrow pewtrusts.org/about/events/2…

Interesting use of a thermoresponsive phage to deliver DNA to the GI tract ncbi.nlm.nih.gov/pubmed/30195771

Very interesting Open Access review of factors contributing to global AMR concludes that reduction of antibiotic consumption will not be sufficient to control AMR reader.elsevier.com/reader/sd/B1FD…

Interesting article on the adaptation of a commercially available phage mixture used for treating UTIs that increased the sensitivity of 118 uropathogenic strains from 41% to 75% frontiersin.org/articles/10.33…

Paratek obtains FDA approval for its antibiotic Omadacycline for treating both acute bacterial skin infections and community-acquired bacterial pneumonia. endpts.com/paratek-clears…

The Director of the Dr Foster Research Unit at Imperial College reports that UK Hospital sepsis deaths have increased by a third in 2 years bbc.co.uk/news/health-45…

Faster DNA sequencing technology developed by Omniome raises $60 million in a Series B funding round endpts.com/faster-cheaper…

Illumina founder launches cloud-based sequencing software Galileo AMR to monitor antibiotic resistance in Gram-negative bacteria endpts.com/illuminas-foun…

Record series A biopharma investment but anti-infectives still fairly small endpts.com/by-the-numbers…

The carbapenem, Tebipenem, offers an oral option, particularly as step-down therapy in the treatment of serious Gram-negative infections. ncbi.nlm.nih.gov/pubmed/30014729

Plant-expressed phage lysins provide better control of C.perfringens on cooked meat than nisin nature.com/articles/s4159…