RO TRIAD

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RO TRIAD

RO TRIAD

@RoTriad

*Unofficial* Stylized Dr. Ro triads from 2pm lectures | tweets ≠ medical advice | #Pathology simplified in 1-2-3 | #AtTheScope #pathologists #pathology

Join us at the scope Katılım Ocak 2015
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RO TRIAD
RO TRIAD@RoTriad·
Helpful features in yolk sac tumor: eosinophilia hyaline globules, basement membrane-like material, Schiller-Duval bodies
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RO TRIAD
RO TRIAD@RoTriad·
Nots of Spermatocytic Tumor: not assoc with ITGCN, not assoc with undescended testis, not seen outside testis
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RO TRIAD
RO TRIAD@RoTriad·
Spermatocytic Tumor: Small lymphocyte-like cells, large cells with, soccer ball-like chromatin, intermediate cells
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RO TRIAD
RO TRIAD@RoTriad·
Beware of testis germ cell tumor cells hiding in prominent granulomatous inflammation. OCT3/4 can help highlight them.
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RO TRIAD
RO TRIAD@RoTriad·
Choriocarcinoma: two cell population (mononuclear/multinucleated giant cell), hemorrhage, spatial arrangement (vague villous configuration)
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RO TRIAD
RO TRIAD@RoTriad·
Seminoma triad: lymphocytes, fibrous bands, clear cells with no nuclear overlapping #RoTriad
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RO TRIAD
RO TRIAD@RoTriad·
Seminoma gross appearance: homogenous, lobulated, bulging
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RO TRIAD
RO TRIAD@RoTriad·
Seminoma cytologic features: distinct cell border, no nuclear overlapping, uniform cells. #RoTriad
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RO TRIAD
RO TRIAD@RoTriad·
Intratubular germ cell neoplasia: clear cytoplasm, nuclear enlargement, prominent nucleolus. Use OCT3/4 to diff btw ITGCN (+) vs other (-)
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RO TRIAD
RO TRIAD@RoTriad·
Three types of testes Germ Cell Tumors (continued)
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RO TRIAD
RO TRIAD@RoTriad·
Always remember to do your BeST!
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RO TRIAD
RO TRIAD@RoTriad·
Reporting lymph node metastasis: number of positive nodes, extranodal extension present/absent, size of largest tumor deposit
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RO TRIAD
RO TRIAD@RoTriad·
Extension of urothelial cancer to prostate: within prostate gland only = T2, with stromal invasion through prostate gland = T4
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RO TRIAD
RO TRIAD@RoTriad·
A few notes on fat invasion in urothelial carcinoma
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RO TRIAD
RO TRIAD@RoTriad·
Remember the 2 types of noninvasive carcinoma in bladder: Ta = noninvasive papillary carcinoma, Tis = carcinoma in situ; give low/high grade
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RO TRIAD
RO TRIAD@RoTriad·
Inverted urothelial papillary lesions: inverted papilloma/PUNLMP, inverted papillary urothelial carcinoma, carcinoma associated w/ papilloma
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