
Rob Fagerlund
251 posts

Rob Fagerlund
@RobFagerlund
Senior Research Fellow @ University of Otago | Studying CRISPR | 🇳🇿
Dunedin City, New Zealand Katılım Temmuz 2017
357 Takip Edilen360 Takipçiler
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It's out🎉Super happy to share our story on the incredible #CRISPR-Cas I-D complex and its mysterious small subunit. Excellent work by @Tess_M_McBride & @AtomicPaparazzo. Shout-out to @davidwtaylorjr, @akhello & @PeterFineran! sciencedirect.com/science/articl…
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Rob Fagerlund retweetledi
Rob Fagerlund retweetledi

Deadline Extension for Abstract Submissions
Good news! The deadline for abstract submissions has been extended to Monday 28 October. This is your chance to showcase your research by submitting either an oral or poster presentation for CRISPR 2025.
#crispr #crispr2025 #phage

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Rob Fagerlund retweetledi

Happy to share our latest story revealing how type III CRISPR-Cas ancillary effectors tactically inhibit translation to combat phage infections: science.org/doi/10.1126/sc…. Here is a thread covering major points: (1/9)
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If you're after some light reading to start your week, here's a short piece I wrote for The Conversation (@ConversationEDU) on our recent anti-#CRISPR regulation work and its relevance for understanding #phage–host interactions:
theconversation.com/viruses-can-wo…
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👋🏻 I'm absolutely glee-ridden to finally see our study on the RNA- and DNA-binding anti-CRISPR repressor Aca2 published in @Nature. 🥳 This unassuming little helix–turn–helix protein packs quite the punch! 🧶👇🏻
rdcu.be/dNl45
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Couple of recent publications from our group!!
1) Awesome work from post-doc Will Jowsey showing how drug-resistance in Mtb alters tolerance to cell wall inhibitors!
doi.org/10.1093/jacamr…
(1/2)
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In our new paper at Cell (@CellCellPress), we reveal secrets of how the third form of life, archaea, make energy. We uncover new lineages of hydrogen-using enzymes, both minimal and complex. These help archaea thrive in all sorts of extreme environments. sciencedirect.com/science/articl…

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@VHoikkala @NilsBirkholz @mfwhite2 @univofstandrews @SchoolofBiology @Skr_fi Excellent paper 🙌 Great seeing this level analysis on (without doubt) the most interesting CRISPR-Cas system 😉
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@SarahCamara94 @cellhostmicrobe @FabBenz @rafapinilla92 Another great piece of work @SarahCamara94 🙌🙌🙌🙌 Congrats to you and all authors on the great story. It's nice to see the mysterious world of type IVs being revealed 🔮✨
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Excited to see our work out now in @cellhostmicrobe ! 🤩 huge team effort, kudos to everyone involved, especially @FabBenz & @rafapinilla92 ! 🫶
Rafa Pinilla-Redondo@rafapinilla92
🎉 Excited to share our latest paper in @cellhostmicrobe! Huge congrats to amazing co-first @FabBenz & @SarahCamara94 (in my profile pic! 🥂) for pushing this work from start to finish! 🚀 1/5 🔗sciencedirect.com/science/articl…
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Rob Fagerlund retweetledi

🎉 Excited to share our latest paper in @cellhostmicrobe! Huge congrats to amazing co-first @FabBenz & @SarahCamara94 (in my profile pic! 🥂) for pushing this work from start to finish! 🚀
1/5
🔗sciencedirect.com/science/articl…

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I am thrilled to share my latest work, out today in @Nature. This project started ~18 months ago as a blueprint for my own lab, which will start at @ISTAustria in July, but not have been possible without the support of @davidwtaylorjr & the whole team
nature.com/articles/s4158…
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@jpkbravo @GraceHibshman @davidwtaylorjr @IlyaFinkelstein Great work @jpkbravo @davidwtaylorjr and team! Cool approaches to reveal the workings of this promiscuous Cas9! 🙌
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I'm so happy to share our SpRY-Cas9 story in its final form! Congratulations to first author @GraceHibshman - it was a great collaboration with a diverse team led by @davidwtaylorjr, including @IlyaFinkelstein and many others... 1/n
rdcu.be/dGkLq
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A couple of delays, but finally managed to attend my induction as a new Fellow of the Royal Society of New Zealand @royalsocietynz @microtago @otago Thanks to all the students, staff and collaborators who enable us to do fun research!


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Cellular repair of DNA breaks enables editing of the human genome.
Do human cells repair RNA breaks, and can we use it to edit transcriptomes?
Our work with @ANemudraia and @WiedenheftLab is now online in @ScienceMagazine!
#ScienceResearch
science.org/doi/10.1126/sc…
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Great to see this out! Always a great time working with the dream team @davidwtaylorjr @PeterFineran @palermo_lab @RobFagerlund and my co-first authors @EvanASchwartz and Mohd Ahsan.
David Taylor@davidwtaylorjr
Great work by former grad student @EvanASchwartz and postdoc @jpkbravo @TexasScience @ut_mbs and Mohd Ahsan @palermo_lab in @NatureComms! Couldn’t happen without long time collaborators @RobFagerlund and @PeterFineran @otago. link.springer.com/10.1038/s41467…
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