Léa Rochet retweetledi
Modular Semisynthetic Approach to Generate T Cell-Dependent Bispecific Constructs from Recombinant IgG1 Antibodies | Bioconjugate Chemistry pubs.acs.org/doi/10.1021/ac…
English
Léa Rochet
144 posts
Léa Rochet
@RochetLea
Chemistry PhD student at @UCL within the @Etntact research project
Katılım Nisan 2012
166 Takip Edilen82 Takipçiler
Léa Rochet retweetledi
Check out this open PhD position in our team!!
✅ Very Cool subject
✅ Very Cool team
✅ Very Cool working facilities
"What else !?"
Don't hesitate to get it touch and candidate!
@SebastienPapot
@IC2MP
English
Léa Rochet retweetledi
🚨PhD Opportunity:🚨
Come and join us and @VijayChudasama_ at UCL Chemistry investigating new chemical methods for empowering antibody conjugates partnered with @GSK! 🧪
See findaphd.com for more info:
findaphd.com/phds/project/3…
English
Léa Rochet retweetledi
Very proud to share our latest collaborative paper with @BakerGroupUCL where we disclose the chemo- and regio-selective differential modification of cysteines on a native antibody; a first-in-class strategy! Led by the fantastic @yapyongyi! @UCLChemistry
pubs.rsc.org/en/Content/Art…
English
Léa Rochet retweetledi
Macrocyclic Dual-Locked "Turn-On" Drug for Selective and Traceless Release in Cancer Cells (Tanja Weil and co-workers) @WeilTanja @Seah_Ling @DominikSchauen1 @VijayChudasama_ @RochetLea @J_A_S_Coelho @Lab_DavidNg #openaccess onlinelibrary.wiley.com/doi/10.1002/an…
English
Léa Rochet retweetledi
We report a dual-lock approach to embed small molecule drugs in cyclic structure, for selective & traceless release in cancer cells.
Congrats to @DominikSchauen1, @Seah_Ling & our collaborators @VijayChudasama_ @J_A_S_Coelho!
onlinelibrary.wiley.com/doi/10.1002/an…
English
Léa Rochet retweetledi
🌟 Happy International Women's Rights Day! 🌟
Today, as we celebrate the incredible achievements of women worldwide, let's also reflect on some important numbers with the different TACT members.
#IWD2024 #WomenInSTEM
English
Just submitted my thesis! 🥹🥳
It's such a bittersweet moment, as I've absolutely loved doing the PhD, but exciting things are coming next!
English
Léa Rochet retweetledi
It's @LorenzoTurelli_ viva! 🇮🇹
Because it's confidential, we had to use our mad Photoshop skills to hide his fantastic work. Can you identify which parts have been edited?
English
@ChaubetGuilhem @EtnTact @IKoutsopetras @Maraniach @yagmurersy @MSCActions It was a pleasure/honour to work on this for my secondment 😁
English
@EtnTact @IKoutsopetras @Maraniach @yagmurersy @MSCActions And @RochetLea thanks to her work during her secondment 😀
English
Léa Rochet retweetledi
Congratulations @ChaubetGuilhem and @IKoutsopetras for a great work developing the Ugi reaction for site-selective protein modification! 👏 A great TACT collaboration too involving the ESRs @Maraniach from LSMBO and @yagmurersy from TUM! @MSCActions
Chaubet Guilhem@ChaubetGuilhem
"𝑻𝒉𝒆 𝑼𝒈𝒊 𝑺𝒕𝒓𝒊𝒌𝒆𝒔 𝑩𝒂𝒄𝒌" Extremely proud to report our follow-up study on the application of the Ugi reaction to protein conjugation, this time with ✨𝐬𝐢𝐭𝐞-𝐬𝐞𝐥𝐞𝐜𝐭𝐢𝐯𝐞 𝐜𝐨𝐧𝐝𝐢𝐭𝐢𝐨𝐧𝐬✨ shorturl.at/jkwGS
English
Léa Rochet retweetledi
"𝑻𝒉𝒆 𝑼𝒈𝒊 𝑺𝒕𝒓𝒊𝒌𝒆𝒔 𝑩𝒂𝒄𝒌"
Extremely proud to report our follow-up study on the application of the Ugi reaction to protein conjugation, this time with ✨𝐬𝐢𝐭𝐞-𝐬𝐞𝐥𝐞𝐜𝐭𝐢𝐯𝐞 𝐜𝐨𝐧𝐝𝐢𝐭𝐢𝐨𝐧𝐬✨
shorturl.at/jkwGS
English
Congratulations to my dear TACT colleagues @Maraniach and @Loic_H10 for the completion of their PhD!! 🥳
TACT-ETN@EtnTact
Let us introduce you to the first two Doctors of the TACT project: @Loic_H10 and @Maraniach! Congratulations to both for their hard work and impressive accomplishments, concluded with an outstanding defense. We wish them all the best for the future! @MSCActions #PhinisheD #TACT
English
Léa Rochet retweetledi
Extremely happy to have this one out! Huge thanks to @baukevon, Floris and @VijayChudasama_ . Thanks and congratulations to you @RochetLea on this. We finally made it. Thank you @EtnTact for this opportunity- almost half the consortium contributed to this work!
Albada Lab@NanoChemBiol
I could not have been more happy with the outcome of this work! Congratulations to @IreneShajan @ORC_PhDs @VijayChudasama_ and many others! Rapid Access to Potent Bispecific T Cell Engagers Using Biogenic Tyrosine Click Chemistry | Bioconjugate Chemistry pubs.acs.org/doi/10.1021/ac…
English
Léa Rochet retweetledi
@NanoChemBiol @IreneShajan @ORC_PhDs Likewise! It was really great to work with lots of @EtnTact people on this, but especially with yourself, Floris, Chris and (of course) @RochetLea + @IreneShajan. Congratulations all!
English
Super happy to see this paper out! Thanks and congrats @IreneShajan @NanoChemBiol @VijayChudasama_ for the great collaboration 😁
Albada Lab@NanoChemBiol
I could not have been more happy with the outcome of this work! Congratulations to @IreneShajan @ORC_PhDs @VijayChudasama_ and many others! Rapid Access to Potent Bispecific T Cell Engagers Using Biogenic Tyrosine Click Chemistry | Bioconjugate Chemistry pubs.acs.org/doi/10.1021/ac…
English
Léa Rochet retweetledi
@VijayChudasama_ Huge thanks to the other authors who enabled to go deeper in the study of those pyridazinediones, @IKoutsopetras, Phyllida Britton, @DKBucar, @ThanasiIoanna, @spearsyrick. Special mention to @dr_mike_porter and Abil Aliev for the DFT and NMR studies!
English
Thanks @VijayChudasama_ for the support over those 3 years, putting this paper together was not the easiest but we did it! 🥳
English
Very happy to finally have this paper out on one of my main PhD work! Huge thanks to everyone who contributed esp Calise Bahou @jono_wojfor for their precious help in developing this study on tuneable pyridazinedione for cysteine modification! Very grateful to @VijayChudasama_ -
Vijay Chudasama@VijayChudasama_
Huge congratulations to @RochetLea on her work on the use of pyridazinediones for tuneable & reversible covalent cysteine modification, a highly collaborative project with @BakerGroupUCL @dr_mike_porter @DKBucar Molly Stevens & Abil Aliev, plus many more! pubs.rsc.org/en/content/art…
English