Rui Huang @ UofGuelph

We would like to share this “swapping” protocol for NMR titrations with our user-friendly scripts hosted on Google-Colab for simulations of simple titration curves, swapping strategy, and early estimation of Kd. Hopefully it’s useful for the community. :)

Introducing in-cyclo NMR, a new method led by @GuillaumeMas2 at @biozentrum (@NatureComms)! This method combines high-resolution NMR with ATP regeneration & phosphate removal to resolve kinetics & dynamics of molecular machines - all in one experiment! doi.org/10.1038/s41467…

Paper link 🔗 ruihuang-lab.com/wp-content/upl… Google-Colab link 🔗 #scrollTo=Ndm-WS8uxzss" target="_blank" rel="nofollow noopener">colab.research.google.com/drive/1ibG-32Z…

We would like to share this “swapping” protocol for NMR titrations with our user-friendly scripts hosted on Google-Colab for simulations of simple titration curves, swapping strategy, and early estimation of Kd. Hopefully it’s useful for the community. :)

Out in @pnas today Showcasing the power of NMR! NMR and enzyme kinetics show USP7 enzyme transiently sampling a low-populated active state, and its disease-causing variant enhancing these dynamics pnas.org/doi/10.1073/pn… Stellar work by students Gabi Valles and Emilie Korchak

@IrinaBezsonova @pnas Congrats!!!!🎊🎈🎉

@bionaloo Congratulations 🎊🎈🍾

Four of our papers ranked as most widely read papers in Wiley publications, topics ranging from aptamers, microplastics to nanozymes. 👏👏

Professor Lewis Kay @LEK_Lab @UofT is honoured with the 2025 Alexander Hollaender Award in Biophysics awarded by the U.S. National Academy of Sciences @theNASciences for outstanding contributions to the field of biophysics utoronto.ca/celebrates/lew… #NMRnews #NMRchat #NMR 🧲

Watch the full interview with Prof. Julie Forman-Kay (@SickKidsNews, @UofT) here: goto.bruker.com/4fWr5yb #Bruker #StructuralBiology #ProteinResearch #ScientificResearch #Innovation

Huge congrats 👏👏 to Rina Rosenzweig who has just been awarded this year’s @ICMRBS Founder's Medal for her truly impressive work on using advanced #nmr to elucidate the complex mechanisms of chaperones. @lab_rosenzweig

@ICMRBS Congratulations to Lewis @LEK_Lab for receiving the Akutsu Award! #NMRchat Great to be here in Seoul!

Had a little celebration yesterday for Lewis in honor of his 500th academic publication! The poster contains the first page of all 500 papers, and his face is made of their figures. Lewis wants to thank all his amazing trainees over the years for making it possible! #NMRchat

If you’ve used UniProt, Ensembl, PDBe, or the AlphaFold Database, then consider helping the EMBL-EBI @emblebi (who hosts these resources) by filling out their survey surveymonkey.com/r/HJKYKTT

@IrinaBezsonova @ReidAlderson @HelmholtzMunich Congrats Reid!!! 🎊🎊🎊

@ReidAlderson @HelmholtzMunich Congratulations 🎉

Very excited to begin my tenure-track position and research group at @HelmholtzMunich with a Young Investigator Fellowship! 🚨I will be hiring 2 PhD students 📝 so if you are interested in #NMR 🧲 , structural biology, #chaperones, or #IDPs, keep an eye out here!

Thrilled to share our work illustrating that a small molecule undergoes picosecond dynamics in its bound state with an intrinsically disordered protein, now out in @J_A_C_S. 🍝💊🧲@DFlemmingHansen @bhu_vaibhav @FigueiredoAm @UCLLifeSciences #NMRchat (1/4) pubs.acs.org/doi/10.1021/ja…

@chris_waudby @AlexGuseman I used to have a free academic version and accidentally clicked ‘upgrade trial’ and lost my academic account. 😢My take-home message is ‘do not upgrade even they said it’s a free trial’😅

@AlexGuseman Yes - it's great to keep access to notes, messages, files from >3 months, particularly when students leave (and I just can't bear working with Teams)

Folks who use slack for the lab, do you use the paid version and is it worth it?

and the published version is now out in @PNASNews! If you are interested in #AlphaFold or intrinsically disordered regions #IDRs, take a look 👇 We've added a lot of new data and analyses. pnas.org/doi/10.1073/pn…

1/7 Ever wondered if there is more to the AlphaFold2 predictions of IDRs than spaghetti 🍝? Isn’t AF2 another disorder predictor? Or has it learned something more subtle and interesting hidden within IDR sequences? To find out, read our new preprint biorxiv.org/content/10.110… 🧵

Group picture (past & present) of the Kay lab members who attended #Moot2023, hosted at @McMasterU! #NMRchat #NMR

A bright future lies ahead for #NMR ! @bhu_vaibhav @G_T_Heller and I have written a review about NMR in the era of AI. Maybe we are biased - but we think that a combination of AI and NMR will further revolutionise structural biology doi.org/10.1016/j.str.… @UCLLifeSciences

“It’s not spaghetti” learning about RNA Editing from the amazing @jenheemstra at the inaugural session of the Tremaine Speaker Series @UofGCEPS join us for one of the amazing presentations this week featuring Dr. Heemstra uoguelph.ca/ceps/outreach/…