SBL Group (VUB)

We're looking for a new postdoctoral researcher to join our team, dealing with the development of new (allosteric) ligands against a range of intra- and extracellular protein targets. Check out the link below or message us for more details! 👩‍🔬 orgc.research.vub.be/open-position-…

We are looking for an enthusiastic PhD student to join our team, looking at the development of new ligands (peptide-based and small molecules) for a diverse range of intra- and extracellular targets. Find out more here: orgc.research.vub.be/open-position-… or message us for more info!

The research in this article has received funding from the European Union’s Horizon 2020 Future and Emerging Technologies program under grant agreement number 858014 (project PANACHE).

Check it out! Here is the cover art for the current issue of the @ACSPublications which contains our most recent article. The paper can be found here: lnkd.in/e5bcnumX #VUB #WeAreVUB #PANACHE

Great presentation by @BalletSteven! Well deserved price!

Congratulations to our 2023 joint Evotec awardee Dr. Steven ballet for the Excellence in Molecular Design Prize ! What a great way to start the day, let’s now enjoy the science. #SCT #RICT2023 #DrugDiscovey #Lille #PrizeWinning

Steven presented the 'Development of Generic G Protein Peptidomimetics Able to Stabilize Active State Gs and Gq Protein-Coupled Receptors for Application in Drug Discovery'. Well done to all who participated! #researchneverstops #SCT 2/2

We are pleased to announce the winner of the 2023 Evotec award for excellence in molecular design, awarded under the auspices of the French Medchem Society (SCT). Congratulations to Professor Steven Ballet, Head of the Research Group of Organic Chemistry 1/2

The research in this article has received funding from the European Union’s Horizon 2020 Future and Emerging Technologies program under grant agreement number 858014 (project PANACHE).

Check out our most recent publication, penned by one of our talented researchers! 👩🏻‍🔬 📚 This article looks at structural features that underpin the pannexin1 channel inhibitory activity of the peptide 10Panx1. #VUB #WeAreVUB #H2020 #PANACHE sciencedirect.com/science/articl…

We have an open position for a #postdoc #postdoctoralresearcher within our group looking at the development of new #peptides for use in #cancer. Are you interested? Check it out here: orgc-vub.login.paddlecms.net/open-position-…

Great way to return from vacation🌴⛱️, seeing our computational work on stacking interactions of halogenated indole derivatives appear online @Pharmaceut_MDPI mdpi.com/1747740 💪teamwork between @SBLgroup_ @MolDesignS and @ALGC_VUB

We are pleased to announce the publication of our latest article "A Quantum Chemical Deep-Dive into the π-π Interactions of 3-Methylindole and Its Halogenated Derivatives" in @MDPIOpenAccess in collaboration with our partners at VUB and KUL! 😍🧑‍🔬 mdpi.com/1424-8247/15/8…

Their work explores the development of next-generation modulators of pannexins and connexins as novel therapeutics in the treatment of #inflammatory #cardiovascular, #hepatic and joint diseases. #PANACHE #H2020 #WeAreVUB

Congratulations to our researchers on the #H2020 PANACHE project who have presented their posters at this year's #GFPP22-#BPGM5. The project has received funding from the European Union's Horizon 2020 Future and Emerging Technologies programme under grant agreement number 858014.

Are you interested in the design and synthesis of biologically active peptides in the sphere of cancer therapeutics? Are you interested in imaging experiments? We are hiring a postdoctoral researcher to work on our oncology track. Find out more: bit.ly/3NlwOj1

Our publication (RSC Medicinal Chemistry, 2021, 12, 828-870) comprises a comprehensive overview of biased ligands and their calculated bias factors, across the whole #opioid receptor family, and even includes bifunctional ligands! #biasedagonism #pharmacology #medicinalchemistry

We are very happy to announce that one of our recent publications on biased pharmacology at the opioid receptors has been selected as a cover art for an upcoming issue of RSC Medicinal Chemistry! Check it out at DOI: 10.1039/D1MD00041A @RoySocChem @VUBrussel @BalletSteven