SIMICA

Our paper on the preclinical efficacy of a highly stable de novo protein decoy against SARS-CoV-2 infection is out! 🥳 @gbernardes_chem @ClaireTang20 @AnaRaquelCoelh5 @neoleukin @IMMolecular academic.oup.com/jid/article/do…

"All those experiences made me who I am." From being a taxi driver to becoming a Nobel Prize laureate - 2018 chemistry laureate @francesarnold describes how a diversity of experiences shapes you as a human being.

🏆 Prof. Gonçalo Bernardes is the recipient of the 2023 EFMC-WuXi AppTec Award for Excellence in Chemical Biology! 🎉 We are delighted to award @gbernardes_chem for his groundbreaking research! #EFMCAward #EFMCWuXiAppTecAward #ChemicalBiologyExcellence #AwardWinner

Generative AI for protein design is now one click away. We've launched a new platform that puts powerful tools behind a simple web interface, making #proteindesign accessible to anyone. Try it here ➡️ huggingface.co/spaces/merle/P… Learn more on YouTube ➡️ youtu.be/bS71K2U0amA

Proud of this work sponsored by SIMICA about a new metal decaging reaction through C–C bond break by palladium. @IMMolecular

Thiomethyltetrazines are reversible covalent cysteine warheads whose reversibility can be "switched off” via live cell bioorthogonal chem, providing stability to lysis/proteomics. Led by @TallonAmanda w/ @Pfizer Mary Xu, Graham West & @ChrisamEnde1 10.26434/chemrxiv-2023-w0p5m

Excited to invite Dr Emma Yates (co-founder & CSO of Proteotype) presenting on Monday Lecture @IMMolecular today! Amazing and interesting talk about developing a novel technique for early stage cancer diagnosis. @gbernardes_chem

This paper is finally out! One of the first examples of a Ru(II) photosensitizer for PDT active at 740 nm!

Tomorrow, Raphaël Rodriguez will present his most recent work about the prevalent role of d-block metals in the regulation of cell plasticity, entitle "Discovery of a metal-driven signaling pathway that regulates cell plasticity". Do not miss it. @institut_curie @immolecular

I am thrilled to announce that Prof. Gonçalo Bernardes @gbernardes_chem from @Cambridge_Uni has joined @BioconjChem as Associate Editor! Gonçalo brings expertise in protein modification, targeted therapeutics, and bioorthogonal chemistry. gbernardeslab.com @ACSPublications

Fluorescent amino acids are getting SMALLER, acid-stable & compatible for peptide-PAINT. Terrific work led by Fabio & Zuzanna with many collaborators. We share Fmoc/Boc analogues for your peptides, get in touch! @MathewHHorrocks @ERC_Research Free link▶️ onlinelibrary.wiley.com/share/author/6…

Angela Casini will be in Lisbon to share some great work on bioinorganic chemistry. Don´t loose this opportunity!!🙂

Congratulations to Rafaela Cavadas, the most recent master @GoisLab, for a very susseceful discussion with @BrunoBioTargtin and @Jpantonio92

Delighted to share the preclinical studies of JS25, a selective BTK inhibitor, with potent efficacy in blood cancers relative to other BTK inhibitors used in the clinic. A special thank you to all the collaborators and to my supervisor @gbernardes_chem. pubs.acs.org/doi/10.1021/ac…

Such an amazing SIMICA meeting this week, a lot of fun, science and nice people. Huge thanks to #SIMICA

Very happy to talk about ADC & bioconjugates from a development and manufacturing perspective at @SIMICA_iMM. This is a side of the history we don’t hear much in R&D and I am so glad with the positive responses! Thanks @gbernardes_chem for the invitation 🤩! @LonzaGroup

Pharma collaborations happening at @SIMICA_iMM. Talk from Catarina Cardoso - Phagecon.

The @SIMICA_iMM summer school is on !!!

Nice @SIMICA_iMM meeting at Octant hotels in Praia Verde!

Fresh from our oven: Traceless cysteine-linchpin enables precision engineering of lysine in native proteins @chm_iiserb @iiserbhopal @serbonline @IndiaDST @rkmisrb1 @sanjeevtmc @NeeleshChandr13 @RAJIB__MOLLA nature.com/articles/s4146…