SLAS

The final #SLASEurope2026 award announcement is here! Meet the 5 New Product Award finalists whose innovations were selected to compete for the coveted award next week in Vienna. Up to 3 winners will be announced in the Exhibition Theatre on Wednesday 20 May at 5:30 local time.

In this week’s episode of the New Matter podcast, Anneke Mühlebach, Director of Marketing Lab Productivity Innovation at Agilent Technologies, joins us to preview the company’s upcoming NexusXp Flash Talk at #SLASEurope2026: slas.org/education/new-….

Targeting ATE1 starts with better tools. This scalable, cell-based HTS assay tracks arginylation-dependent degradation in real time opening the door to discovering selective, safer ATE1 inhibitors: slas-discovery.org/article/S2472-… @UFScripps

Targeting NLRP3 to control inflammation: a cellular HTS + target engagement workflow screens 2.5K compounds, validating 10 inhibitors (7 novel) across inflammasome checkpoints—highlighting diverse mechanisms and therapeutic potential: slas-discovery.org/article/S2472-…

From @ucsf - When Sypro Orange falls short, go bigger. Aurora 2.0 expands paDSF to 517 dyes, achieving 94% success across challenging protein unlocking broader, high-throughput protein stability analysis: slas-discovery.org/article/S2472-….

From @ufresearch.bsky.social in September's SLAS Discovery: Stop the virus before it gets in. A 5HB-targeted HTS (635K compounds) finds 41 selective inhibitors and 5 standout hits with validated activity against viral entry: slas-discovery.org/article/S2472-….

Targeting BRD4 and RIPK3 to fight arsenical-induced injury: HTS of 4,000+ compounds yields 18 dual hits and 3 potent candidates (<10 μM) with anti-inflammatory activity. A step toward effective countermeasures: slas-discovery.org/article/S2472-….

Who will compete for the #SLASEurope2026 Ignite Award? Severine Thomas-Lousteau, CEO at Novoptim and member of the Innovation AveNEW and Ignite judging panel, reveals this year’s finalists...

SLAS Discovery: More groups=more false positives. Simulations show ANOVA + Tukey’s often lets too many through especially with small sample sizes. A simpler fix? Bonferroni on pre-selected comparisons delivers better control w/o sacrificing much power: ow.ly/IUnj50YVm9L.

When IBD therapies stop working, better models matter. A new immune–epithelial co-culture recreates key inflammatory responses (TEER ↓, cytokines ↑) and shows rescue with known drugs—built for high-throughput screening and faster translation: slas-discovery.org/article/S2472-….

With excitement building ahead of the #SLASEurope2026 Ignite Award finalist announcement, hear from @XDemics CTO & Co-Founder Colin Cook, PhD, on what winning the award at #SLAS2026 meant to his team: slas.org/education/new-….

In our hands-on Applied Liquid Handling Bootcamp, participants gain the experience needed to refine protocols, anticipate challenges and build more robust, efficient workflows through instruction and real-world troubleshooting scenarios. Learn more: bit.ly/4w91qLU.

I went to America's largest lab automation conference (@SLAS_Org) to see the bleeding edge of lab automation first-hand. Three things stood out: a big focus on instrument interoperability (shoutout @SiLAStandard, @UniteLabs_), new efforts to generate large experimental datasets (shoutout @AtinaryTech), and the big bet many are chasing – fully autonomous science (a la @Ginkgo x @OpenAI's recent collab on cell-free protein synthesis). The excitement is real. And, so are the risks if we take our eyes off the less glamorous parts of the R&D process – like optimizing clinical trials. Join me inside SLAS. Full vid: youtu.be/DDivALKEqf8

AI-powered automation is redefining how samples are stored, tracked, and retrieved, but adoption doesn’t happen overnight. Join industry experts for an experience-driven discussion on the path from innovation to implementation at this virtual @SLAS_Org Technology Idea Exchange (TIE) event. If you’re considering, planning, piloting, or scaling automation, this session on April 29, 12pm ET will help you move forward with confidence. Free SLAS account required to register. Reserve your spot: hubs.ly/Q04ddML80 #SampleManagement #ColdStorage #AutomatedSampleStorage

It’s time to announce the five finalists selected to compete for the #SLASEurope2026 Student Poster Award. Here's CEO Vicki Loise for the official announcement...

From SLAS Discovery: Faster Cell Painting, sharper insights. Early readouts (~6h) capture primary drug effects more accurately than standard 48h assays boosting specificity, reducing noise, and accelerating high-throughput screening workflows. ow.ly/Rw1O50YMkjh

Inefficient freezer farms and spreadsheet inventory tracking weren’t built for today’s fast-moving science. Join us April 29 at 12pm ET for an @SLAS_Org Technology Idea Exchange (TIE) presentation on Automating Cold Storage with Confidence to hear how AI-driven automation is improving traceability, scalability, and confidence across cold storage operations and sample management. If you’re navigating growth, complexity, or legacy infrastructure, this conversation is for you. Free SLAS account required to register. Reserve your spot now: hubs.ly/Q04ddr6M0 #SampleManagement #ColdStorage #SampleAutomation

New assay, new clues for neurotoxicity. A CRISPR-engineered MT1G::HiBiT neuronal model enables high-throughput screening linking metal-chelating compounds to neurotoxic signals and advancing discovery of Parkinson’s risk factors. slas-discovery.org/article/S2472-… @NIHRresearch

From @OMassTx: New tool for ion channel discovery: the “Glorider” BRET biosensor tracks chloride dynamics in real time in living cells enabling high-throughput screening of WNK, KCC2, and NKCC1 modulators for drug development. slas-discovery.org/article/S2472-…

Join us at ETH Zurich next Thursday for an afternoon of discussion and networking featuring Olivier Frey, Dr. Sc (InSphero), who will present “Scaling up 3D cell-based assays in numbers and information content.” bit.ly/4d5KI7F