Rahul Satija

Excited to share VIPerturb-seq! New tech from my lab which aims to improve the cost, data quality, and efficiency of single-cell CRISPR screens so that they are accessible to any lab - even at genome-wide scale Preprint and 🧵 (1/): biorxiv.org/content/10.648…

A history of viral encephalitis is one of the strongest risk factors for developing dementia. With @JacobJacobog02, Yifan Chen, @RNA_Life, and @RyanDhindsa, we refine this link by describing a neuronal cell type that can reactivate HSV-1 in humans 1/n biorxiv.org/content/10.648…

Interested in single cell genomics but need help getting started? Come to my lab's 10th (!) Single Cell Genomics Day on 6/12 Talks include Aviv Regev @anshulkundaje @junyue_cao @xinjin + (many) more + @ATJCagan illustrations! Free Youtube livestream at satijalab.org/scgd

PerturbFate is officially out in @Nature today! From chromatin to RNA, we dissect the causal regulatory logic linking genotype to phenotype. Huge thanks to my PhD advisor @junyue_cao @Wei_Zhou_1989, and @RockefellerUniv for providing such an incredible research home!

We’re unwrapping a new method today @MSKCancerCenter! Led by @SydneyBlattman, @NabihMaslah, @AustinAVarela, Ronan Chaligne and @dana_peer, plus colleagues at @10xGenomics, we’re delighted to share Genotyping In Fixed Transcriptomes (GIFT): biorxiv.org/content/10.648… 1/n

We’re excited to announce the launch of Gencove Consumer! $49 for a sequencing-based genetic baseline. Built for individuals who want to better understand their health and for a future where genetics is standard in every consumer health product. 👇 enterprise.gencove.com/blog/introduci…

New paper alert 🚀 Our organism-wide single-cell ATAC-seq atlas of mammalian aging is now out in @ScienceMagazine, led by our fantastic graduate student @ziyu__lu from @RockefellerUniv! science.org/doi/10.1126/sc…

Join us at Cell Symposia: Single-Cell Biology in the Era of AI (Dec 2–4, 2026, Munich) 🇩🇪 From multi-omics to AI-driven models of cellular dynamics — an exciting lineup across experimental & computational biology. Hope to see you there! 🔗 cell-symposia.com/single-cell-bi…

Excited to share VIPerturb-seq! New tech from my lab which aims to improve the cost, data quality, and efficiency of single-cell CRISPR screens so that they are accessible to any lab - even at genome-wide scale Preprint and 🧵 (1/): biorxiv.org/content/10.648…

Congratulations and many thanks to lead authors @alex_bradu (who runs our single cell genomics day!), and John Blair (@jblairsci.bsky.social). And to our funders @genome_gov (via @cegs_ica), @SMaHTnetwork, and @cziscience

Learn more and try it out at satijalab.org/viperturb-seq/ And lots more to come! With @CalebLareau’s lab, we’ve shown that VIPerturb-seq is compatible with RNA-based enrichment (#VIPerff), and we’re excited to share this soon.