Scleroderma News

A genetic analysis identified existing medications that could be repurposed as potential scleroderma treatment options, a new study reports. sclerodermanews.com/news/study-sug…

Levels of anti-CD146 antibodies may help identify SSc associated with occupational exposure to silica and other mineral dusts, a study found. buff.ly/gcARnGm

The scleroderma drug AISA-021 safely reduced Raynaud’s attack frequency and duration in a study but still failed to meet its primary goal. buff.ly/G4Hbr3S

Hand baths enriched with carbon dioxide were found to ease symptoms of systemic sclerosis-associated Raynaud’s phenomenon in a small trial. buff.ly/TTuOCHp

SSc-ILD treatment use has increased over time, with registry data showing fewer lung disease progression events. buff.ly/BwJXcvl

Soluble CD13 levels are elevated in people with scleroderma, but may not reflect disease severity, a study finds. buff.ly/6Qv9JpE

Lab findings support the clinical investigation of stem cell-based interventions for systemic sclerosis-related interstitial lung disease. buff.ly/FBKA4xP

Macrophages, a type of immune cell, may be mainly responsible for driving fibrosis (scarring) in people with scleroderma, a study found. buff.ly/r6Alv8A

Abnormal fatty acid metabolism may play a role in the development of systemic sclerosis, according to a gene activity analysis. buff.ly/YxSLPcE

A type of laser therapy used to get rid of wrinkles may help reduce skin scarring in people with localized scleroderma, a study found. sclerodermanews.com/news/laser-the…

Lower blood levels of immunoglobulin G (IgG) were linked to worse health-related quality of life in systemic sclerosis, a study reports. buff.ly/A7Yi85W

Anti-SSA antibodies were linked to shorter survival and faster disease progression in systemic sclerosis in a Japanese study. buff.ly/gahwNnm

Dexamethasone reduced skin thickening, inflammation, and the activity of genes that induce fibrosis in a mouse model of SSc, a study found. buff.ly/vaWMhon

Combination therapy for pulmonary arterial hypertension improves survival in people with systemic sclerosis, a large study in Australia found. buff.ly/ppBMy4F

A combination drug therapy was more effective than using either one alone at boosting skin and lung health in people with SSc, a study found. buff.ly/tv42ZPD

Telerehabilitation is more effective than self-managed exercises at increasing hand mobility in women with scleroderma, a study found. buff.ly/sZ0WFEh

A molecular signaling pathway called EGFR-STAT1 is key in driving fibrosis, or scarring, in scleroderma, according to a new study.  buff.ly/fhGEuYq

Limited function in hands affects the daily tasks, work, psychological well-being, and social activities of adults with SSc, a study shows. buff.ly/1HkZle6

For columnist Tomisa Starr, living with scleroderma involves coping with the loss of her old self as well as the loss of friends. buff.ly/og7L2Kk

An experimental CAR T-cell therapy showed manageable safety, eased skin thickness, and improved lung function in SSc, per early trial data. buff.ly/rmEXZGP