Shijun Deng

@jasonhyang @ma_lab_cgidr Congratulations!

I'm thrilled to share that the lab has received its first R01!! Together with Shuyi Ma (@ma_lab_cgidr) and Christoph Grundner, we will be exploring how M tuberculosis gene networks regulate drug tolerance. More soon, but we will be recruiting postdocs and graduate students!

Congratulations to Dr. Renata Goncalves @RenataG81952725 @gshlab for being recognized by Boston Area Nutrition Obesity Research Center Outstanding Manuscript Award @BostonAreaNORC for her studies on discovering a CoQ metabolism defect leading to reverse electron transport and site-specific ROS production in mitochondria as a mechanism disrupting hepatic metabolism 🧿👏 bostonareanorc.org/awards/outstan…

@dchloechung Congratulations

We are officially an NIH-funded lab!! Super grateful for my NIA K22 Career Transition Award 🥳 It will support setting up the initial research program in our new lab at Rutgers, investigating the fascinating biology of big tau. As always, big thanks to my mentors/collaborators 🙏

@gshlab @gparlakgul @ghotamis Congratulations @ghotamis hocam!

Nature research paper: CLCC1 governs ER bilayer equilibration to maintain lipid homeostasis go.nature.com/4rzQTXg

The Hotamışligil Lab is hiring! We are looking for an Assistant Director of Strategic Alliances. More info here: linkedin.com/jobs/view/4291…

@apsarruda @gparlakgul Congratulations Gunes and Alessandra!

Congratulations to Gunes Parlakgul @gparlakgul and Alessandra Ferrari, the newest Faculty members of NST department at @ UC Berkeley!!

@gparlakgul @apsarruda @BerkeleyMetBio Congratulations Ana🎉

So proud of Ana @apsarruda , my partner in life and in science, for this incredible achievement! Well deserved! 👏🥳 @BerkeleyMetBio pew.org/en/about/news-…

@rushika_perera @RosaMenjivarPhD @kioneillphd @GillesRademaker @graceah9 @marineberquez @YangYan55648779 Congratulations!

Promoted ! 🙌

Thrilled by #NLASessions ! Foundation of Lipidology course brilliantly bridged basic science to clinical practice. 🔑 takeaways: real-world LLT challenges and novel therapeutic targets. Thank you to the organizers & faculty! Excited to apply these perspectives to my research!

Excited to share our latest paper led by Renata Goncalves @RenataG81952725: CoQ imbalance drives reverse electron transport to disrupt liver metabolism. nature.com/articles/s4158… We uncover how altered CoQ redox balance triggers RET and rewires hepatic metabolism to offer critical insights into a decades old question. Meticulously mapping each one of the 11 sites of the mitochondrial electron transport chain in the liver showed site IQ as the sole source of excess mitochondrial ROS, produced via reverse electron transport. This defect is driven by CoQ imbalance in obesity, disrupts glucose metabolism. These findings may have implications for many diseases and open up new treatment possibilities where broad antioxidants have failed to generate therapeutic benefit. Our findings may also offer a potential mechanism and solution for the increased diabetes risk seen in a small fraction of statin users. Huge congratulations to Renata Goncalves @RenataG81952725 for leading this work and for her immense dedication and patience to bring it to a conclusion. Congratulations to all contributors from the @hotamisligil lab and our amazing collaborators Isabel Graupera @igraupe and Shawn Burgess @Isotopomer Curious? The 93-page-long peer review file is full of useful information and insightful discussions.

@rushika_perera @Nature @GillesRademaker Congratulations!

Online today in @Nature - our latest study led by superstar postdoc @GillesRademaker detailing the role of PSCK9 in driving sterol dependent metastatic organ choice in pancreatic cancer nature.com/articles/s4158… full text available here 👉 rdcu.be/em0VG and thread 👇

@realTonyHui @yuanbogeneral Congratulations!

Happy to share the final version of this work where we incorporated isotope labeled CO2 data into mass spec-based flux analysis framework to build a whole-body flux model of energy metabolism. Full article access here: authors.elsevier.com/a/1keM55WXUlaX… @yuanbogeneral

@yjgaoustc Congratulations, you are very well deserved!

Extremely excited to share a fantastic opportunity for a tenured professorship and chair position in our department @MET_HSPH in broad areas of metabolism. We are looking for an outstanding scholar with stellar research accomplishments, demonstrated leadership and administrative abilities, and a compelling vision for the department to join our vibrant environment. Anyone interested in this position or would like more information or to nominate a candidate, feel free to contact directly or reach out through the ad. @Harvard @HarvardChanSPH #facultyposition g.co/kgs/x8Qte7j

@AWeinstock Congrats!

Celebrating summer ⛱️🌞 and the 2nd birthday of the Weinstock lab with this amazing group 🤩🤩 I cannot believe at how much these scientists accomplished in so little time - they are THE BEST!

@XinGu0317 @DFCI_CancerBio @HarvardCellBio Congratulations and welcome!

I'm thrilled to join @DFCI_CancerBio and @HarvardCellBio as a tenure track assistant professor Sept 2024! The Gu lab elucidates mechanisms underlying cellular homeostasis, with our initial effort on nuclear protein turnover by the ubiquitin-independent midnolin-proteasome pathway

@echouchani @HHMINEWS @DanaFarber @HarvardCellBio congratulations!

I am thrilled and honored to join the @HHMINEWS community. So grateful to my lab, colleagues at @DanaFarber @HarvardCellBio, and collaborators whose work this reflects!

Obesity disrupts the pituitary-hepatic UPR communication leading to NAFLD progression dlvr.it/T95ws3

@ghotamis @KathrynMooreLab @InstitutFrance Congratulations 👏

@KathrynMooreLab @InstitutFrance Congratulations Kathryn, very well deserved 👏👏🧿🧿

Honored to receive the Grand Prix Scientifique of the Fondation Lefoulon-Delalande - @InstitutFrance with Chris Glass.