Shmuel Shoham

At our best infectious diseases experts can act as the synapses that connect surgeons, internists, pharmacists, microbiologists, epidemiologists and the patients to make good decisions.

Triazole-resistant Aspergillus fumigatus in the Netherlands between 1994 and 2022: a genomic and phenotypic study - The Lancet Microbe thelancet.com/journals/lanmi…

Two Pandemics, Compared: Reflections on HIV and COVID-19 blogs.jwatch.org/hiv-id-observa…

@AndrewMCameron wow!

Johns Hopkins Surgery without the surgeons! More BlueJay innovation… hub.jhu.edu/2025/07/09/rob…

@Bastards_Boston This team is starting to develop an identity and Duran is part of that. Players who can hit, run, play solid, defense (or are working on improving it), don't give up, and have an aggressive streak.

JARREN DURAN If he’s traded for just a package of prospects… That’s totally:

A great opportunity for those wanting to learn and update themselves about infections in transplant and oncology patients.

hopkinsmedicine.org/infectious-dis… We are excited about this course. We are sure @Contagion_Live readers will find this course worthwhile

Aspergillus tanneri fast facts: Tends to be resistant to multiple antifungal agents, described in people with chronic granulomatous disease (CGD) Western parts of US, living in Western parts of the US. Disseminated and contiguous disease patterns

Clinical situation: should you use vancomycin as part of empiric therapy in patient with AML and pneumonia. Answer from clinical trial: Not typically, if MRSA screen is negative - Talagtag - 2021 - Transplant Infectious Disease - Wiley Online Library onlinelibrary.wiley.com/doi/10.1111/ti…

@ross_prager Yes, but... medica school and residency and some fellowships, can be unforgivingly hard. So, it is ok to give yourself a break if you can't be happy during stretches of this time

(9/10) Medical school (and residency) are marathons - don't delay living your life until they finish. This is a big one. Don't justify unhealthy lifestyles, unhappiness, or complete imbalance in your life simply because "once I'm done medical school it gets better". The truth is, the skills you develop to balance your life (in medical school and residency) set you up for a happy, prosperous, and meaningful career. For many of us, we spent our 20s and early 30s in training. If you aren't finding joy along the way, this probably warrants some reflection.

Here are 10 lessons they don't teach in medical school (but should) that I've learned the hard way over the years. 🧵 (0/10)

Candida auris: a) adheres to skin and inanimate objects, b) colonization often clinically significant (compared to C. albicans), c) associated with outbreaks, d) often resistant to fluconazole, and sometimes echinocandins too. A good review article by Lionakis in NEJM in 2024

Teaching case: middle aged man with ulcerative colitis. Disease has been stable, but now seemingly flares. CMV viral load ~100K. Endoscopy: CMV colitis. CMV IgG had been negative previously. Now CMV IgM+. This is probably primary CMV infection with tissue invasive disease

For a patient in whom there is a high pre-test probability for Clostridium difficile infection: a positive C difficile PCR with a negative EIA for toxin, does not rule out C difficile. False negative tests for the EIA toxin do occur.

most people voted for AmB, which would be my choice too

ID quiz: pt with neutropenia and blood culture with Rhodotorula. What is your fist line antifungal therapy

more about this organism and the skin Seroy J, Antiporta P, Grim SA, Proia LA, Singh K, Clark NM. Aspergillus calidoustus case series and review of the literature. Transpl Infect Dis. 2017 Oct;19(5). doi: 10.1111/tid.12755. Epub 2017 Sep 19. PMID: 28741738.

Aspergillus calidoustus. I have seen it have a tendency for cutaneous involvement. Tends to be resistant to azoles. Here is another one from the literature. rdcu.be/eg2Fr.

@JessicaLittleMD terrific review.

20/ 💥 Take-home points on CNS #cryptococcus (2) 📍High dose corticosteroids may benefit pts with evidence of #PIIRS if CSF cx are negative 📍NEVER underestimate intracranial pressure 🧨🧨🧨- continue to LP until normalized x2 days [can use shunt also] The end.

1/ A brief 🧵 on a challenging case of #cryptococcal meningitis #IDtwitter #TxID #MedTwitter @PaulSaxMD @PergamIC @FungalDoc @transplantID @boulware_dr @GermHunterMD

Thank you to today’s panel of MMI Thursday Seminar presenters — David Sullivan, MD, & our guests from @HopkinsMedicine moderator Dan Hanley, MD, @ShohamTxID, Nicole McBee & Karen Lane! Great interactive discussion about their multi-center #COVID-19 clinical trial

Estimates of actual and potential lives saved in the United States from the use of COVID-19 convalescent plasma | PNAS pnas.org/doi/10.1073/pn…

share.transistor.fm/s/e9646ad0 new episode up: invasive candidiasis