Dott. Simone Parisi

🧲🤩 Thrilled to share our new @eular_org #classification criteria for #HaemochromatosisArthropathy! A long-overlooked, iron-driven arthritis finally gets the attention it deserves. Proud to have contributed to this international effort. See 👉🏼POS0558 #EULAR2025 #rheumatology

🚀4th edition of #Reumasport has just concluded Challenging the paradigm: patients with rheumatic diseases are not fragile → they are trainable💪 🔥Multidisciplinary approach, exercise as therapy,real-world vision 🚀 #ReumasportStudyGroup is now launched IG: @reumasport_official

🤔Does prior IL-17i exposure affect retention in PsA? 🌍Real-world data from the BIRRA Study Group (868 patients across 24 centres) suggest no major impact. 💡Evidence supporting IL-17i cycling in selected patients. 🔗 link.springer.com/epdf/10.1007/s… #PsoriaticArthritis #Rheumatology

🎙️ New podcast by EMEUNET With Patrick Kiely, we discuss haemochromatosis arthropathy 🔎 When to suspect it 🦴 Key clinical & radiographic clues 💡 Practical take-home messages 🎧 urly.it/31d-n5 #Rheumatology #Haemochromatosis #EULAR #MedicalEducation

🎉EULAR 2025 Classification Criteria for Haemochromatosis Arthropathy 📘 Ann Rheum Dis 👉 ard.eular.org/article/S0003-… Proud to be part of this international effort led by Patrick Kiely with amazing colleagues, @EULAR_org & patient partners. Thanks to @EMEUNET for the opportunity! 💪

🧩 New publication “Guselkumab effectiveness in real-world settings: Italian multicentre study” 🔗 doi.org/10.1093/rap/rk… 📌26 Italian rheumatology centers (BIRRA network) 📊 278 PsA patients #PsoriaticArthritis #Rheumatology #RealWorldEvidence #IL23 #Guselkumab #BIRRAstudy

🔎 #Ultrasound as a diagnostic tool in #PMR New study @Rheumatol_Int ➡️Bilateral subacromial-subdeltoid bursitis > 3 mm can reliably distinguish Polymyalgia Rheumatica from rotator cuff tendinopathy. 📊 Specificity: 96.3% 📊 Sensitivity: 84.2% 👉urly.it/31c08f

🧐Granulomatosis with polyangiitis #GPA can present as a diagnostic emergency.A multidisciplinary approach led to timely treatment despite no initial biopsy. Later confirmation: necrotizing vasculitis.Teamwork saves lives.😎 👉🏼urly.it/31b8f2 👀 #vasculitis #rheumatology

Thanks to @EMEUNET for giving me the opportunity to be part of this Eular Task Force @k_lauper @KragstrupTW

A landmark moment at #EULAR2025 🏛️ Patrick Kiely presented the EULAR Classification Criteria for Haemochromatosis Arthropathy (HA) — the first-ever criteria for this long-neglected yet disabling condition. #Haemochromatosis #Arthropathy #EULAR2025 #ClassificationCriteria

👏 Kudos to the international task force and patient research partners across 10 countries for this rigorous, data-driven achievement!

🧠 Joint pain in C282Y homozygous patients? Think beyond OA. Think HA. 📍 MCP 2–3 involvement, hook osteophytes, early onset, and the iconic “iron fist” are now part of a validated scoring system (specificity 93.3%, sensitivity 71.4%).

📢Don’t miss the presentation of the brand-new EULAR Classification Criteria for Haemochromatosis Arthropathy! 🗓️June 14,09:45–10:00 📍Room D1 | Session: EULAR Recommendations II 🎙️Speaker:Patrick Kiely #EULAR2025 #Rheumatology #Haemochromatosis #Arthropathy #EULARRecommendations

🔵Poster POS0334 | #EULAR2025 Colchicine still matters in mucosal #Behçet: 📈Withdrawal led to significant ↑ in oral ulcers at 12 weeks (2.7 vs 0.9; p<0.001) 🔹Higher relapse in women 🔹Also impact on other mucocutaneous lesions. #BehçetSyndrome #Vasculitis #Colchicine

🟣 Poster POS0333 | #EULAR2025 Apremilast shows efficacy in refractory mucosal #Behçet’s syndrome: 🔹93.5% OU response 🔹↓ Ulcer scores 🔹Transcriptomics: downreg of interferon & monocyte pathways 📉Relapse rate still ~43%, but molecular data suggest targeted immune modulation.

🧠🫀From EGPA to GCA and ANCA-AAV: exciting insights from poster tours at #EULAR2025! 🧪GC-sparing, PET/CT radiomics,avacopan, OCT biomarkers & MMP-3 for PMR-mimics,vasculitis research is evolving fast. 🔍Science meets clinical relevance! #Vasculitis #Rheumatology #EGPA #GCA #AAV

💪 Finally! At #EULAR2025, a whole session dedicated to the role of sport in RMDs 🙌 From evidence to practice, from inflammation control to pain relief, sport is medicine. 🧠 “A DMARD and a painkiller”? Yes, with data to back it. #RheumTwitter #ExerciseIsMedicine #RMDs

RESET-SSc: CAR-T for SSc 🧪The RESET-SSc trial with rese-cel (anti-CD19 CAR-T) shows: ✅B cell depletion in blood & tissue ✅Skin & lung improvements by Week 24 ✅Drug-free response for ≥6 months ✋Nailfold capillaroscopy shows vascular recovery #CAR_T #SSc #Immunotherapy

Digital ulcers&antifibrotic strategies 🧤Long-term use of selexipag improves SSc-DU outcomes in multicentre data 🧬Tadalafil may modulate skin fibrosis & gene expression in SSc 🧠CRISS & AI trajectories explored in SSc patients on CD19.CAR-T #SystemicSclerosis

🌿 An inspiring & high-impact session on #SystemicSclerosis at #EULAR2025! From vasodilators & PAH therapy to gene modulation and CAR-T for drug-free responses. Here’s a thread with the highlights 👇 #SSc #Vasculopathy #RheumTwitter