ski9704

Acrylic organizer box 📎 s.shopee.co.id/3fxBsvueo3

@jcplie I've seen people buy like mini telescopes for their phones. U.S stadiums allow them as long as they're less than 6inch in length (or at least So-Fi and Allegiant Stadium)

j’ai le même téléphone que la go mais faut voir comme ma qualité est degeu je comprends pas …

Im so serious about this

Allow your friends to distance themselves to fix their lives not everything is about you.

someone said “when you lose the emotional attachment to them, you begin to realize how ordinary they are, and that it was your love and energy that made them unique” and i seriously couldn’t have worded it better

I dont talk to people unless they talk to me.

do not bring anybody to my house with you unannounced

having your silly interests validated and supported by the people u love is a really important way to actually show love

An EXPIRED friendship is NOT beef.

my cousin jung josé posting about benito another win for mi gente latino

THIS IS THE FUNNIEST, MOST LATINO THING HE COULD’VE DONE #SuperBowl #SuperBowlLX

Many of you may have missed this, but the little boy who Bad Bunny handed his Grammy to at the Super Bowl was Liam Ramos! Amazing!

anyone who makes you sad on your birthday hates you

i can be really mean when i’m overstimulated

OH SHE ATE THIS SOOO BAD LMAOOO ICONIC😭😭😭

this girl is genuinely so pretty and her style is beautiful…. changbin, MOVE

College+ showed me a lot of mfkers weren’t parented or even raised. Just housed, fed, and tolerated until it was legal to unleash them on the rest of us

Yes, this is the way ppl. Free those in the detention centers.

This isn’t a random scientist who got lucky. Mariano Barbacid discovered the first human oncogene in 1982. He isolated H-RAS from bladder cancer cells and proved a single point mutation could trigger cancer. That finding launched the entire field of molecular oncology. KRAS mutations cause 90% of pancreatic cancers. For 43 years, oncologists called KRAS “undruggable” because the protein had no obvious binding pocket. Barbacid spent the last decade using genetically engineered mice to systematically test every node in the KRAS signaling pathway, looking for combinations that would work without killing the patient. The triple therapy blocks KRAS three ways at once: the main growth signal, the escape routes through EGFR and HER2, and the stress-response backup through STAT3. Cut the engine, seal the exits, disable the emergency system. Tumors vanished in mice and didn’t return for 200+ days after treatment stopped. Pancreatic cancer has a 13% five-year survival rate. 8% for the ductal adenocarcinoma type this therapy targets. Most patients live one year after diagnosis. The catch: this is preclinical. Human trials are 3+ years away. One of the drugs, RMC-6236, might get approved this year, but the full triple combination has regulatory hurdles. Still. The man who discovered human oncogenes in 1982 may have just figured out how to eliminate the cancer those genes cause. That’s a 43-year arc from first principles to potential cure. Science rarely works this clean.

I won’t shut up about this, pancreatic cancer kills a person in 4 months btw, it’s resistant to radiotherapy, and fucks two essential parts of the metabolism. this could change the world