Sleebs Lab retweetledi
In @Sleebs_Lab @WEHI _research discovered the ADHQ chemotype exemplified by WJM590 that exhibits potent antimalarial activity by inhibiting plasmepsin X. #ACSInfectiousDiseases
go.acs.org/er1
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Sleebs Lab
218 posts
Sleebs Lab
@Sleebs_Lab
Medicinal Chemistry and Chemical Biology Research Laboratory @WEHI_research #cancer #malaria #infectiousdiseases | views are our own
Melbourne, Victoria, Australia Katılım Aralık 2021
615 Takip Edilen533 Takipçiler
Pleased @Sleebs_Lab @WEHI_research played a small role in the published research on the discovery of Plasmodium RBC invasion inhibitors lead by Claudia Barnes and Hayley Bullen @BurnetMalaria
sciencedirect.com/science/articl…
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Want to know which plasmepsins are the most promising targets of the next generation of antimalarials. Find out in the recently published review by @Sleebs_Lab @WEHI_research
doi.org/10.1002/med.70…
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Pleased @Sleebs_Lab contributed a small role in remarkable team led by Paola Favuzza and Alan Cowman @WEHI_research and David Olsen and John McCauley at MSD that developed MK-7602 now in clinical development for the treatment of malaria.
thelancet.com/journals/ebiom…
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Please to share @Sleebs_Lab @WEHI_research latest research led my @MadelineDans and @Wenyin_Su demonstrating the on-target activity of plasmepsin V peptidomimetics in Plasmodium falciparum parasites using genetic and proteomic approaches.
pubs.acs.org/doi/10.1021/ac…
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Please @Sleebs_Lab @WEHI_research has contributed to a review at @npjAMR led by Emma Mao @UniofAdelaide on the contribution of natural products to the drugs approved to treat disease caused by apicomplexan parasites
nature.com/articles/s4425…
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Pleased to see our research is published @Sleebs_Lab @WEHI_research led by William Nguyen on the optimization of an antimalarial class that targets ROM8 & CSC1
...stay tuned for more research on the intriguing role of ROM8 & CSC1 in parasite survival...
pubs.acs.org/doi/10.1021/ac…
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Sleebs Lab retweetledi
Truly honoured to receive the #MCCB2025 Peter Andrews Award for Innovation in Medicinal Chemistry and Chemical Biology. Grateful for the recognition of our work at @NitscheLab and @ANUChemistry! Congratulations to @PScammells on the well-deserved Adrien Albert Award!
Yu Heng Lau@YuHengLau
Congratulations to our @RACInational MCCB Division award winners, delivering their lectures this morning in Darwin: @PScammells - Adrien Albert award @NitscheLab - Peter Andrews award 👏👏👏 #mccb2025
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Sleebs Lab retweetledi
Exciting Day 3 @RACI #MCCB2025 ! Starting with showstopping stories from GateBioscience's Pat Sharp on the development of Sec61 #inhibitors for Prion disease, & Prof. Avril Robertson @UQ_News on targeting NLRP3 #inflammasomes. Impressive preclinical efficacy fromin both stories!
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Pleased @Sleebs_Lab @WEHI_research has contributed to research led by Aya Taki @UniMelb on the prediction and prioritization of novel anthelmintic candidates using deep learning is published at Int J Mol Sci. mdpi.com/3245704 #mdpiijms via @IJMS_MDPI
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Pleased to see our research @Sleebs_Lab @WEHI_research lead by Tony Hodder on the structural analysis of dual plasmepsin V and plasmepsin X inhibitors is now online at FEBS. febs.onlinelibrary.wiley.com/doi/full/10.11…
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Pleased to see the review lead by Harry Shanley @Sleebs_Lab @WEHI_research in collaboration with the Gasser Lab @UniMelb on Advances in Anthelmintic Target Identification is now published. mdpi.com/3270800 #mdpiijms via @IJMS_MDPI
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Pleased to see our latest research lead by Kyle Awalt and Zi Kang Ooi @Sleebs_Lab @WEHI_research on the investigation of a novel class of antimalarials that target PfATP4 published is now online at the Journal of Medicinal Chemistry. pubs.acs.org/doi/10.1021/ac…
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Sleebs Lab retweetledi
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Sleebs Lab retweetledi
Congratulations to @UpamaliSajinika from our lab for receiving the poster prize at the #MCCB2025!
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A big THANK YOU to all MCCB 2025 sponsors & exhibitors! Your support drives innovation & makes this conference possible🌟 #MCCB2025
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Sleebs Lab retweetledi
Many thanks to the organisers of @RACInational #MCCB2025 for the invitation to share our work on #TB. It was a really enjoyable conference - learning about new medicinal chemistry and chemical biology research and catching up with the #OzChem community!
Ludovica Monti@LudovicaMonti
Fantastic talk from @Leung_Group at @RACInational #MCCB2025 on resolving complex metabolic networks to tackle TB!
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Sleebs Lab retweetledi
Very happy to have contributed to @RACInational #MCCB2025 in Darwin! A fantastic opportunity to connect with brilliant colleagues from around the world. Such inspiring discussions!
Big thanks to the organisers for hosting an amazing event!
School of Chemistry | University of Melbourne@ChemistryUoM
Dr Ludovica Monti @LudovicaMonti @ChemistryUoM delivered a keynote lecture on her recent work the use of genomics to identify novel drug targets in neglected tropical diseases at the Infectious Disease session of the @RACInational #MCCB2025
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