Stefano Longo

I am really happy to share that my first first-author paper “Sex differences in durability following heavy intensity cycling exercise in trained athletes” has been published in the Scandinavian Journal of Medicine & Science in Sports 🎉 link: dx.doi.org/10.1111/sms.70…

Exercise delays brain aging through muscle-brain crosstalk. The younger your muscles, the younger your brain.

Final PhD study is out 🦶 Slow, high-load eccentric calf training leads to the greatest acute Achilles tendon thinning (↓8.9%) & stiffening (↑54.5%)—suggesting more fluid exudation & lower intratendinous pressure. 🏋️ Loading speed & intensity matter! 🔗 journals.lww.com/acsm-msse/abst…

Effects of Eccentric Exercise of the Extensors on Eccentric Exercise-Induced Muscle Damage of the Flexors in Limbs Medicine & Science in Sports & Exercise journals.lww.com/acsm-msse/full…

Data in recreationally-active older adults from: Horwath O et al. Ageing leads to selective type II myofibre deterioration and denervation independent of reinnervative capacity in human skeletal muscle. Exp Physiol. 2025 Feb;110(2):277-292. doi.org/10.1113/EP0922… Data in masters strength athletes from: Tøien T et al. The impact of life-long strength versus endurance training on muscle fiber morphology and phenotype composition in older men. J Appl Physiol (1985). 2023 Dec 1;135(6):1360-1371. doi.org/10.1152/japplp…

Sex differences in muscle hypertrophy peerj.com/articles/19042/ via @PeerJLife Great work from @MartinRefalo @GregNuckols @DrAndyGalpin @jacksonfyfe

Intramuscular contributions of impairments in sarcoplasmic reticulum calcium release, myofibrillar calcium sensitivity & myofibrillar force on prolonged low-frequency force depression are task dependent: brnw.ch/21wQrKx @chenglabyorku @WesterbladHakan @mhrc_yorku

Do you use ultrasound imaging to look at muscle architecture changes during movement? Then UltraTimTrack is for you! We leveraged the benefits of its predecessors, UltraTrack+TimTrack, to enable automatic, objective, and accurate fascicle tracking - peerj.com/articles/cs-26… 💪🦵🦶

🚨New article from our lab!🚨 -Previous short-term disuse dictates muscle gene expression and physiological adaptations to subsequent resistance exercise- A true collaborative effort! (see the thread below for more) Now out in @JPhysiol physoc.onlinelibrary.wiley.com/doi/full/10.11…

Exercise is medicine: The new global exercise guidelines for healthy longevity in older adults are here. With exercise recommendations to address >14 chronic diseases, adverse outcomes, and geriatric syndromes including: ✅ Falls ✅ Cancer ✅ Dementia ✅ Type 2 diabetes ✅ Depression and anxiety A key focus is the need for personalised exercise prescription and translating the evidence to practice. “The ultimate goal is enhanced quality of life, regardless of age or initial state of fitness or frailty.”

Does increasing training volume over the amount they had already been doing have a big impact on muscle size and function in those who are classified as resistance trained Not really journals.physiology.org/doi/abs/10.115…

Another piece to the puzzle. In this paper, we show how muscle-tendon unit decoupling can contribute to the SSC effect. Collaborative work by Denis Holzer (@TU_Muenchen), @WolfgangSeiberl, and Tobias Siebert (@Uni_Stuttgart) Funded by @dfg_public OA: doi.org/10.14814/phy2.…

🚨📢Paper alert! Real progress on identifying why residual force enhancement occurs! This was a study I dreamed about since grad school. Please share! The distinctive mechanical and structural signatures of residual force enhancement in myofibers | PNAS pnas.org/doi/10.1073/pn…

Are there sensitive periods for physical activity to influence the development of executive function in children? doi.org/10.1016/j.jshs…

An editorial Tom Hawke and I wrote to highlight the important research contributions of Ned Debold and Håkan Westerblad to our understanding of skeletal muscle fatigue mechanisms: journals.physiology.org/doi/full/10.11…

NEW PAPER: From Tissue to System: What Constitutes an Appropriate Response to Loading? Out now in Sports Medicine: link.springer.com/article/10.100… So pleased to be able to work with Eric Oetter from the Memphis Grizzlies on this one!

The ECM appears to play an important role in exercise-induced hypertrophy. It may have particular importance during passive tension (see: PMID 34101193). Both papers are great reads and provide potential mechanistic insight into muscle development journals.physiology.org/doi/full/10.11…

What a great effort guys 🥰

New in @MSSEonline -Distinct Neural Drives along the Semitendinosus Muscle- Very nice! happy to see growing interest in the neuromechanics of hamstrings -with @AndreCasolo @snuccio87 @AlecsDelVecchio & Co we have novel data related to this -> soon! pubmed.ncbi.nlm.nih.gov/39160760/