SunyBiotech🐛

Reward to our Followers: From May 1st, everyone who follows @SunBiotech on Twitter/X will be able to enjoy 15% OFF for one gene-editing strain! The discount is valid for 3 months. Thank you to all our followers for your trust! Contact📧service@sunybiotech.com

High-quality lipoproteins = reliable data Working on lipid metabolism, atherosclerosis, or inflammation? The quality of your LDL reagents can directly impact your results. At SunyBiotech, we provide high-purity, cell-culture-ready human LDL products designed for: --Foam cell formation & atherosclerosis models --Endothelial & smooth muscle cell studies --Inflammatory signaling & lipid uptake research Our portfolio includes: • Modified LDL: Ox-LDL, Ac-LDL, High Ox-LDL • Fluorescent LDL: DiI-LDL, DiI-Ox-LDL, DiI-Ac-LDL • Native fractions: Human LDL, VLDL Whether you're starting a new project or optimizing assays, we’ve got the tools to support your research. 📩 Email us for details or quotes: sunybiotechteam@gmail.com

CRISPR Knock-In in C. elegans With CRISPR/Cas9 sequence knock-in, researchers can precisely insert functional tags—such as GFP, mCherry, wrmScarlet, FLAG, HA, or 6×HIS—directly into endogenous gene loci. At SunyBiotech, we provide ready-to-use templates for: 🟢 Green fluorescent tags 🔴 Red fluorescent tags 🔵 Blue fluorescent tags 🟡 Yellow fluorescent tags Helping you design and build the custom C. elegans strains your research needs. 📩 Email us: sunybiotechteam@gmail.com

Visualizing Mitochondria in Living C. elegans Mitochondria are central to energy metabolism, aging, and neurodegenerative disease. Understanding their dynamics requires tools that allow researchers to observe them directly in vivo. Using mitochondrial trackers, researchers can fluorescently label mitochondria to: --Monitor mitochondrial distribution in different tissues --Study mitochondrial dynamics such as fission and fusion --Evaluate mitochondrial health under stress, aging, or drug treatment --Investigate mitochondrial dysfunction in disease models In C. elegans, mitochondrial tracking enables real-time visualization of cellular energy systems within a genetically tractable organism. At SunyBiotech, we help researchers build the custom gene-edited strains and experimental platforms needed to support mitochondrial biology studies. Turn mitochondrial signals into biological insight. Contact us: sunybiotechteam@gmail.com

Whole-Gene Deletion in C. elegans Sometimes the best way to understand a gene’s function is to remove it entirely. At SunyBiotech, we provide precise whole-gene deletion services in C. elegans, allowing researchers to completely eliminate gene function and study the resulting phenotypes with clarity. ✔ Full gene knockout ✔ Designed to ensure complete loss of function ✔ Applicable even for large gene loci Whether you're investigating gene function, disease mechanisms, or pathway biology, a clean deletion model can provide powerful insights. 📩 Email us to learn more: sunybiotechteam@gmail.com

Tissue-Specific Rescue to Dissect Gene Function Understanding where and how a gene functions often requires precise tissue-specific rescue experiments. In C. elegans, extrachromosomal rescue is a fast and highly cost-effective strategy to restore gene expression in selected tissues and evaluate functional relevance. Why choose extrachromosomal rescue? ✔ Rapid generation timeline ✔ Flexible promoter selection for tissue specificity ✔ Budget-friendly option — $500 for 3 strains ✔ Ideal for functional validation before stable genome editing Need long-term stability? Your rescue construct can also be integrated into the genome to obtain heritable, stable lines. Accelerate your functional studies with the right strategy. Email us for details: sunybiotechteam@gmail.com

Multiple insertion in C. elegans? We’ve got you covered. Need multi-copy insertion for stronger expression or complex genetic designs? At SunyBiotech, we offer two efficient strategies—tailored to your project goals: Option 1： Generate an extrachromosomal array, then integrate it into the genome via X-ray irradiation to obtain a stable, heritable line. Option 2： Achieve direct targeted insertion using CRISPR/Cas9 for precise genomic integration. Whether you prioritize speed or genomic precision—we help you choose the right strategy. From design to validated strain, we make it simple. Email us for a quick go/no-go discussion: sunybiotechteam@gmail.com

Oxidized LDL (Ox-LDL)-on sell Low-Density Lipoprotein (LDL) plays a central role in transporting cholesterol to peripheral tissues and the liver for bile acid synthesis. It is widely used to study receptor-mediated endocytosis and lipid metabolic pathways. When oxidized, Ox-LDL becomes a critical tool in disease research: -Study lipid oxidation in atherosclerosis -Induce oxidative stress in cells -Model apoptosis and cellular injury -Investigate LDL functional and metabolic alterations Accelerate your lipid metabolism and cardiovascular research with reliable experimental tools. Contact us: sunybiotechteam@gmail.com

Anticancer Drug Screening with C. elegans At SunyBiotech, we offer in vivo anticancer drug screening using C. elegans models that recapitulate key oncogenic signaling pathways. Ras & Notch Pathway Models Our worm models mimic hyperactivated cancer pathways, enabling evaluation of compounds targeting oncogenic signaling networks. For example, hyperactivation of EGFR/Ras signaling (e.g., let-23 or let-60 mutations) induces the multi-vulva (Muv) phenotype, providing a clear and quantifiable readout for drug efficacy. -Rapid in vivo screening -Pathway-focused evaluation -Cost-effective preclinical insight Contact us: sunybiotechteam@gmail.com

Advancing Disease Research with C. elegans At SunyBiotech, we provide comprehensive C. elegans model construction and gene editing services to accelerate your biomedical research. As a powerful in vivo, high-throughput model organism, C. elegans demonstrates significant genetic and physiological conservation with humans, making it an ideal platform for disease modeling and translational studies. We develop customized disease models to support research in: Tumor, Aging models, Neurodegenerative diseases, Metabolic disorders, Infectious diseases Our tailored models help uncover disease mechanisms, identify therapeutic targets, and evaluate drug efficacy and safety prior to clinical translation. Contact us: sunybiotechteam@gmail.com

Accelerate Your Anti-Aging Drug Discovery with C. elegans At SunyBiotech, we provide comprehensive C. elegans Anti-Aging Drug Screening Services to rapidly evaluate the efficacy of potential longevity compounds. We provide C. elegans Anti-Aging Drug Screening Service to quickly test the efficacy of potential anti-aging drugs. We offer flexible solutions(traditional compound evaluation or our high-throughput screening platform) designed for speed and cost-effectiveness. Contact us: sunybiotechteam@gmail.com

Why C. elegans is a powerful platform for drug & chemical screening Early-stage screening demands speed, biological relevance, and scalability—and C. elegans delivers all three. With highly conserved pathways in metabolism and aging, this in vivo model bridges the gap between cell-based assays and mammalian studies. At SunyBiotech, we combine custom gene-edited strains with comprehensive CRO services, including: • Aging mechanism exploration • Anti-aging drug screening • Development of healthy aging–related products All to deliver reliable and reproducible screening data. Smarter screening starts in vivo. E-mail us: sunybiotechteam@gmail.com

Mapping protein interactions in living worms—TurboID makes it possible TurboID-based proximity labeling enables the capture of transient and tissue-specific protein interactions in vivo. By endogenously tagging a protein of interest with TurboID, researchers can: • Identify local protein interactomes • Resolve cell- or tissue-specific complexes • Track dynamic interactions during aging, stress, or disease progression Turn proximity into insight. Build your custom TurboID C. elegans strains with us: sunybiotechteam@gmail.com

Human disease often begins with a single gene mutation—so why not model it directly? By introducing human-relevant gene mutations into C. elegans, we can build robust aging and neurodegenerative disease models that recapitulate conserved molecular pathways involved in Alzheimer’s, Parkinson’s, ALS, and longevity regulation. Through precise gene editing, these models enable: • Functional analysis of disease-associated variants • Dissection of aging-related genetic pathways • Rapid, in vivo drug and modifier screening • Mechanistic validation before mammalian studies At SunyBiotech, we generate customized mutant strains and support downstream phenotyping, lifespan assays, neurodegeneration analysis, and stress response testing—delivering reproducible, grant- and publication-ready data. Contact us: sunybiotechteam@gmail.com

Applying for funding—but concerned about generating strong preliminary data? High-quality, reliable, and reproducible results are often critical for a successful grant application. Tight timelines, limited resources, and technical uncertainty can make this stage especially challenging. At SunyBiotech, our team brings over 10 years of experience in C. elegans research, delivering publication- and grant-ready data through precisely engineered strains and a full range of C. elegans-based experimental services. Email us to learn how we can support your next funding application: sunybiotechteam@gmail.com

Why C. elegans is a powerhouse for mitochondrial research？ Mitochondria control energy metabolism, stress responses, and aging—and many mitochondrial pathways are highly conserved from worms to humans. In C. elegans, researchers can: -Dissect mitochondrial dynamics (fission/fusion, mitophagy) -Model mitochondrial diseases & metabolic disorders -Screen compounds that rescue mitochondrial dysfunction -Track age- and stress-dependent mitochondrial decline in vivo At SunyBiotech, we support mitochondrial studies with: ✔ CRISPR gene editing (KO, KI, point mutations, reporters) ✔ Endogenous tagging for mitochondrial proteins ✔ Stress assays (oxidative, heat, hypoxia) ✔ Aging & drug screening CRO services From gene to function, from phenotype to mechanism. Email us to have a discussion: sunybiotechteam@gmail.com

See your protein exactly where it works With precise sequence knock-in, researchers can insert custom sequences—GFP, mCherry, wrmScarlet, FLAG, HA, 6×HIS, and more—directly into endogenous gene loci. SunyBiotech capability highlight: • Successfully completed knock-ins up to 6 kb • 5–8 week turnaround for knock-in projects Why it matters: Research applications include: • Aging research – monitor age-dependent changes in protein expression and localization • Neuroscience – track neuronal protein dynamics and synaptic localization • Tumor models – visualize pathway-specific protein activity in vivo • Protein dynamics – quantify expression, trafficking, and degradation under stress or drug treatment Build precise, publication-ready strains—on time. 📩 sunybiotechteam@gmail.com

New Year, New Strains—Make Them Stable! Still watching your extrachromosomal arrays disappear generation by generation? With X-ray irradiation, we can integrate your extrachromosomal rescue into the genome, turning transient expression into stable, heritable lines. Start 2026 with strains that actually stick around. Contact us: sunybiotechteam@gmail.com Why integrate? -Stable inheritance across generations -Consistent expression -Reduced maintenance & re-injection -Ideal for long-term aging, tumor & drug studies

Hello 2026 — and thank you, researchers worldwide! We’re deeply grateful for the trust and collaboration of scientists who supported SunyBiotech grow into one of the leading C. elegans service providers—from gene editing to aging research, tumor models, stress assays, drug screening, behavior analysis, and omics services. In 2026, our commitment remains the same: 🔹 Be your most reliable research partner 🔹 Deliver precise, efficient, and reproducible services 🔹 Support bold science with strong technical foundations What’s new this year? Beyond C. elegans, we now offer gene editing in bacteria (E. coli) and yeast, alongside expanded capabilities in oligonucleotide synthesis and protein expression/synthesis—enabling end-to-end support from sequence to function. New Year Offer: Enjoy 30% OFF your first bacteria (E. coli) and yeast gene editing project with us. Here’s to another year of discovery, innovation, and partnership. 📩 sunybiotechteam@gmail.com

Happy New year from SunyBiotech! As the year wraps up, we’re grateful to support researchers advancing science—one worm at a time. From CRISPR/Cas9 gene editing to RNAi screening, aging & neurodegeneration models, drug screening, behavior analysis, stress assays, and omics services, we help turn C. elegans into powerful biological insights. Thank you for trusting us with your research in 2025. Here’s to discovery, precision, and breakthroughs in the year ahead! Our email:sunybiotechteam@gmail.com

Fun Fact-Most engineered metabolic pathways are first built in bacteria—not because they’re simple, but because they’re predictable. Precise bacterial gene editing allows clean pathway rewiring without developmental noise. 30% OFF your first bacterial / yeast gene edit Email: sunybiotechteam@gmail.com Ideal for fermentation, biomanufacturing & synthetic biology.