Synapse Research Institute

In the upcoming weeks we will highlight presentations of our #thrombinconference. This week’s selection is a presentation on #TG, #bleeding and #haemophilia, by Stephen MacDonald. bit.ly/3GNYYR1 #thrombingeneration

In the upcoming weeks we will highlight presentations of our #thrombinconference. This week’s selection is a presentation on the history of #SynapseResearchInstitute, by Bas de Laat. #thrombin #thrombingeneration #TG synapseresearchinstitute.com/introduction-a…

We are excited to announce that the online #ThrombinConference 2021 will be organized from October 12-15th and proud to present the program with exciting speakers and online meeting sessions. Registration is now open & free of charge lnkd.in/dYFytuAj

@dawelian @safespanya It was a very nice presentation!

La semana que viene presentaré en el Forum #APS de Maastricht nuestros datos que revelan que 1 de cada 4 mujeres con problemas reproductivos tienen positivos anticuerpos anti-fosfolipido. #SAF #nosolotrombos #inmunoweb @safespanya

Hemostasis during Extreme Exertion This review summarizes recent literature on the effect of #extremeexertion of both short and long duration on #coagulation, #fibrinolysis, and recovery of #hemostaticbalance. ow.ly/Xn2j30l7QBh

Dr. Hilde Kelchtermans gave an interesting lecture about thrombin generation in APS patients. #APS #APSpatients #highriskAPS #thrombingeneration #ISTHSSC2018

Since we have a Scanning EM available at Synapse Research Institute, very interesting collaborations have been going on. Below is shown how a fibrin biofilm covers a blood clot and protects it from microbial invasion. ow.ly/izti30kNGYP

Implication of Free Fatty Acids in Thrombin Generation and Fibrinolysis in Vascular Inflammation in Zucker Rats and Evolution with Aging #thrombingeneration #fibrinolysis #freefattyacids ow.ly/VvQH30l7R1A ow.ly/PeaE30l7QUs

Interesting Review in Nature Reviews: Antiphospholipid syndrome APS can present with a variety of clinical phenotypes, including thrombosis in the veins, arteries and microvasculature as well as obstetrical complications. #APS #thrombosis #APSphenotyes ow.ly/k05q30l7QLs

@NASTandH @RPTHjournal If confirmed, the observation may have practical implications for dental procedures, as performing invasive procedures in the morning could be beneficial for rapid coagulation. Might be relevant for patients with a bleeding tendency or on oral anticoagulants; to reduce bleeding.

@RPTHjournal Seems like there could be practical application of this if confirmed?

New #RPTH Brief Report finds that tooth extraction and #dentalsurgery in the morning may be better for rapid coagulation than other times of day due to rhythm of salivary tissue factor activity. Read here: doi.org/10.1002/rth2.1…

Inside Blood Commentary: The antiphospholipid syndrome finally fathomed? bloodjournal.org/content/131/19… #thrombosis @SynapseBV

A reminder of our APS forum this year in Maastricht. If you didn't sign in yet, check the website! ow.ly/dlzL30kMLJt

Did you know that: Prothrombin conversion is accelerated in the antiphospholipid syndrome and insensitive to thrombomodulin. This article is published in collaboration with Vascular Medicine Division, Centre Hospitalier Régional Universitaire in Nancy. ow.ly/forY30kMMfB

Effects of Plasmin on von Willebrand Factor and Platelets: A Narrative Review Published in collaboration with the Department of Clinical Chemistry and Hematology, Gelre Hospitals in Apeldoorn (The Netherlands). Image: Model of VWF cleavage by ADAMTS13 ow.ly/DLlV30kMKWq

In the past few weeks we were working hard on the new regulations of the recent GDPR. We made it, but it took a lot of energy!

Suzanne Zwaveling won the Young Investigator Award at the ISLH 2018. She gave her presentation on: "Dabigatran and rivaroxaban differentially affect fibrinolysis".

The antiphospholipid syndrome finally fathomed? ow.ly/nmgY30k7EPB

Lecture at the ISLH 2018 by Professor Coen Hemker: "Thrombin Generation: Concept; Methodology; Pitfalls and Evolution".

So many new innovations currently at our Research Institute. Our research is just as exciting as watching a James Bond movie!

Synapse Research Institute and Ghent University Hospital initiated a European multicenter study to measure antibodies in order to obtain more information on APS (the AntiPhosholiphid Syndrome). This "APS multicenter study" is still running and results are promising!