TransplantDirect

The May issue of @TXPDirect is jam-packed with useful information for our diverse international transplantation readership. We welcome you to visit our Transplantation Direct website for full details in open-access. #OpenAccess #TransplantTwitter bit.ly/TXDissue

Pediatric-to-pediatric kidney transplants show strong adaptability: smaller donor kidneys grow rapidly—reaching age-appropriate size within ~6 months—and support good function, reinforcing this strategy as safe and effective. #TXPforAll #OpenAccess tinyurl.com/47797cac

Genetic testing is reshaping kidney transplant evaluation: over one-third of candidates had a genetic diagnosis often clarifying cause and guiding donor decisions. #TXPforAll #OpenAccess #Transplantation tinyurl.com/3zuejwwc

This paper by @nerecugo et shows that a slow-release form of necrostatin-1 using PLGA microparticles helps to protect islets under stress preserving insulin function and reducing inflammation.#TXPforAll #Transplantation #OpenAccess tinyurl.com/3dp4p3by

New SLK/KAL allocation rules show promising results: few patients needed SLK, many recovered kidney function after liver transplant alone, and outcomes after SLK and KAL were similar. #TXPforAll #Transplantation #OpenAccess tinyurl.com/yzz3k9uz

Research by Tector and coworkers shows that pig SLA-12 behaves like classical class I molecules and can bind peptides, form surface complexes, and attract human antibodies—suggesting it may be an additional xenoantigen to consider in xenotransplantation. tinyurl.com/t8u6f632

NMP may not fully rescue livers after prolonged cold ischemia—longer storage led to poorer recovery or increased injury in a pig DCD model. #TXPforAll #Transplantation #OpenAccess tinyurl.com/4cprrnkz

High Hb (concentrated blood) impaired cardiac function and increased hemolysis, while whole blood and plasma better preserved heart performance over time. 👉 Diluting Hb may be key to optimizing heart preservation during ex situ heart perfusion. tinyurl.com/4zhwz8kk

3 kidney transplants between identical twins performed with no immunosuppression ✅ Up to 22 years follow-up ✅ Excellent graft function ✅ No rejection episodes Supports immunosuppression-free transplant as a safe, effective option in monozygotic twins. tinyurl.com/5x67yx7d

🚨 Kidney care gap: In South Africa, 79% of patients needing KRT received no treatment and were presumed dead. Access to dialysis/transplant favored younger, healthier, wealthier patients.💡 Transplant saves lives but capacity limits decide who gets it. tinyurl.com/3pujenpx

Retroperitoneoscopic nephrectomy . • Similar surgery time, blood loss & kidney size • BUT muscle damage was dramatically lower with RN • Better long-term cosmetic outcomes. RN + kidney transplant is safe, less invasive, and kinder to the body. tinyurl.com/3yn8bada

Can IVIG change the game for post-transplant antibody deficiency is addressed in this study. This shows adding IVIG to standard care may significantly reduce infections and boost humoral immunity in solid organ transplant recipients with secondary antibody deficiency.tinyurl.com/2dbv7mur

Analyzing gene expression in kidney transplant biopsies, study reveals clear molecular differences between rejection types; TCMR and AMR each show distinct gene signatures. Yet, patient-to-patient variability reminds us: rejection isn’t one-size-fits-all! tinyurl.com/y4djk7c3

This paper discusses what transplant patients are really talking about online. It explores 1,000 posts from Reddit’s transplant community and reveals how patients share experiences, seek support, and navigate life after solid organ transplantation. tinyurl.com/43fjaepk

The April issue of @TXPDirect is jam-packed with useful information for our diverse international transplantation readership. We welcome you to visit our Transplantation Direct website for full details in open-access. #OpenAccess #TransplantTwitter bit.ly/TXDissue

Over 20 years of data show that DCD islets perform as well as DBD islets—with a trend toward better diabetes reversal. A promising way to increase donor availability for type 1 diabetes treatment. #TXPforall #Transplantation tinyurl.com/4p255ryk

Can alkaline phosphatase (ALP) protect donor kidneys? In a porcine model, adding ALP during preservation improved energy status and reduced metabolic stress after reperfusion. Promising strategy to reduce delayed graft function #TXPforAll #Transplantation tinyurl.com/muyxpww6

❤️ This study by Rosethal et al. shows that clinical follow-up + echocardiography (TDI) may safely monitor rejection, with high graft survival and low detection yield from routine biopsies. Less invasive care looks promising! #TXPforAll #Transplantation tinyurl.com/cnwc64wr

Milestone reached! Our community has grown to 11,000 followers on X/Twitter. Researchers, clinicians, & transplant enthusiasts around the world who share, discuss, & advance the science of transplantation together. Thank you for being part of this growing community! #TXPforAll

Does the logistics of normothermic machine perfusion matter in liver transplantation from donation after circulatory death donors is discussed in this paper by Alderete et al. #TXPforAll #Transplantation #OpenAccess tinyurl.com/4zjt47ae