Takaku_lab

MSCA Postdoctoral Fellowships 2026 hosting offer - at the Eda Yildirim Lab of Koc University - MBG, Türkiye euraxess.ec.europa.eu/jobs/hosting/m…

I am excited to have been awarded a Wellcome Trust CDA fellowship. This award allows us to dissect the mechanistic basis for trophectoderm lineage commitment across scales, from atoms to embryos. dundee.ac.uk/news/wellcome-…

We are looking to hire a Postdoctoral Fellow to join the Eda Yıldırım Lab at Koç University through the Koç University Postdoctoral Researcher Support Program. Please share with potential candidates in your network!

We develop cf-EpiTracing, a new liquid biopsy tl to trace tissue origin and therapy responses using cell-free multimodal chromatin states from as little as 50 ul plasma, now @Nature. Congrats to Xubin, Xiaoxuan, etc. Big thks to many many collaborators! nature.com/articles/s4158…

Nucleosome aficionados! Our new review "Nucleosome spacing across cell types, diseases, and ages" is out in NAR: academic.oup.com/nar/article/54… A huge effort to pull together what we’ve learned about nucleosome spacing in many systems. Enjoy! #nucleosomics #nucleosome #chromatin #cfDNA

🚨 Today in @Nature, we report GEMINI—a genetically encoded intracellular memory device that writes cellular dynamics into tree-ring-like fluorescent patterns within cytoplasmic protein assemblies.[1/n] nature.com/articles/s4158…

Our collaborative study with Yasui lab @sciencetokyo_ja is out in @ScienceAdvances ! With gRNA/GeNL tagging, we showed that cancer-derived small EVs can reach and be concentrated in urine via transcytosis, providing rationale for urinary liquid biopsy. science.org/doi/10.1126/sc…

Masahiro Nagano and I were fortunate to collaborate with the Vos&Farnung labs: CTCF dimerization drives higher order nucleosome assemblies. Disrupting CTCF dimerization in cells weakens CTCF loops and causes growth + differentiation defects. biorxiv.org/content/10.648…

My student @Aoi_Otsuka_’s PhD work is now officially published @CSF_JSCB! 🔬Single-nucleosome imaging uncovers biphasic local chromatin dynamics in an oncogene-inducible human carcinogenesis model (1–3 d: same, 5–7 d: ↑, back by week 4). Congrats! 👏 jstage.jst.go.jp/article/csf/51…

Happy to see my last piece of postdoc work online—nearly two years after it first appeared on bioRxiv. Title: Live-cell single-molecule dynamics of eukaryotic RNA polymerase machineries science.org/doi/10.1126/sc…

Our latest paper is now out in @jclinicalinvest! 🎉Huge congrats to superstars🌟 @simongarinet & @karlsemaan on this study with @sylvanbacalab #FreedmanLab @drchoueiri. [1]

Our paper on the transcription-coupled H3K36me3 deposition is finally out! We found that histone methyltransferase Set2 deposits　H3K36me3 specifically on the reassembled nucleosome in coordination with FACT.  Great collaboration with Sekine Lab!  science.org/doi/10.1126/sc…

Notice of Temporary Extension to Early-Stage Investigator (ESI) Eligibility Period grants.nih.gov/grants/guide/n…

Notice of Temporary Extension of Eligibility for the NIH Pathway to Independence Award (K99/R00) grants.nih.gov/grants/guide/n…

Our breakthrough AI model AlphaGenome is helping scientists understand our DNA, predict the molecular impact of genetic changes, and drive new biological discoveries. 🧬 Find out more in @Nature ↓ goo.gle/4bXlV6y

胡桃坂計画研究代表による成果がScience Advances誌に掲載されました! Structural basis of transcription-coupled H3K36 trimethylation by Set2 in coordination with FACT science.org/doi/10.1126/sc…

Please RT urgently🔁 My group at UBC got an allocation by the school to apply for Canada Impact+ Research Training Awards (postdoc). Everything is moving fast in Canada. Please email me in 72 hours with CV if you are outside Canada and interested😎 sshrc-crsh.canada.ca/en/funding/opp…

🔬 Calling all early-career researchers (ECRs) for the GRS Single Molecule Approaches to Biology! 🌎 Location: Les Diablerets, Switzerland 📆 Save the date: June 27-28, 2026 🔗 More information: grc.org/single-molecul… #biology #biophysics #singlemolecule #microscopy #ECR

McGill University (@mcgillu) has many open faculty and postdoctoral positions with generous funding packages, thanks to Impact+ grants, which are investing $2 billion to attract global talent to Canada 🇨🇦🇨🇦🇨🇦. Associate/Full Professor: $8 million startup package Assistant Professor: $600K startup package Postdoc: $70K (starting salary) If you are interested and work in the space of AI/ML/NLP/LLMs, please reach out to me. #AI #NLProc #ML

Thrilled to share @gungulati's perspective piece in @JCO_ASCO describing how expression-based liquid biopsy will help guide a new wave of cancer treatments.