Cédric Gobet

Huge thanks to everyone involved! More to come soon!

We combined RNA-seq, Ribo-seq, tRNA quantification, and proteomics to study BCAA starvation. Valine codon stalling creates elongation bottlenecks. Codon identity, tRNA dynamics, and amino acid levels shape translation and protein output. #Translation #MolecularBiology #BCAA

🚨 Two new preprints on BioRxiv! 🚨 We’re excited to share two complementary studies built on a shared dataset, exploring how cells regulate translation elongation under amino acid starvation, from computational and biological angles. 🧠 + 🧬 = 🔬💥 Read on 👇

Indeed, looking forward to this collaboration with you @molina_lab! @epflSV @cziscience

Now online! Circadian tumor infiltration and function of CD8+ T cells dictate immunotherapy efficacy dlvr.it/T6cbr6

Proud to share the results of our study on the effect of prostaglandin E2 on T cells, which was just published in Nature in which we discovered a new role for PGE2 in inhibiting interleukin-2 (IL-2) sensing and signalling in tumor-reactive T cells nature.com/articles/s4158…

@KevinVerstrepen @NatureComms @guardian @KU_Leuven @VIBLifeSciences @JonathanSobel1

Our new paper “Predicting and improving complex #beer flavor through #MachineLearning learning” is out in @NatureComms ! Read how we used #AI to make #belgian 🍺 even better: rdcu.be/dCyGX Comments in @guardian theguardian.com/technology/202… @KU_Leuven @VIBLifeSciences

@TerritorioTrail @taka_does_stuff

#BM100 | Dos de los tres primeros son franceses ( podrían ser Aurelien Sánchez y Maxime Gauduin) y el tercero Jared Campbell (sí, el dos veces finisher está de nuevo en #bm100 ).

#BM100 | 6 corredores han completado el primer “loop”. Los tres primeros en 8:30:59 seguidos de cerca por el otro grupo de tres. Todavía no sabemos sus nombres. #bm100

🕰️ The 'Towards clinically actionable molecular biomarkers of the circadian clock' symposium in Venice has just kicked off. Looking forward to insightful discussions ahead! #CircadianResearch #WarwickInVenice

I am excited to share our latest contribution to the RNA velocity field, which encapsulates a dedicated effort by my graduate student @alexlederer19 to improve its statistical foundations and focus on its inferential value to ask scientific questions. 1/10 biorxiv.org/cgi/content/sh…

OPPORTUNITY: we have an Assistant Professor opening at @EPFL_en in Life Science Engineering. Outstanding candidates across ALL areas of Life Sciences will be considered! Please circulate. Screening starting on Dec 15.

Very happy that our article "Uncovering personalized glucose responses and circadian rhythms from multiple wearable biosensors with Bayesian dynamical modeling" is now online in Cell Reports Methods! (doi.org/10.1016/j.crme…) A brief overview... (1/5)

Excited to share our latest #research paper: "Mice with humanized livers reveal the role of hepatocyte clocks in rhythmic behavior." Deep dive into our findings here: science.org/doi/10.1126/sc… #CircadianBiology #Chronobiology

Aurelian Sanchez completed loop five and has finished the 2023 Barkley Marathons in 58:23:12. A bit of a challenge near the end - a day hiker removed one of the books, believing the race was over. #BM100

Nos chercheur·e·s ont découvert comment le sexe et l'âge influencent notre horloge biologique, en analysant les rythmes d'expression des gènes. Cette étude pourrait aider au diagnostic et au traitement du trouble du sommeil et des maladies métaboliques. actu.epfl.ch/news/comment-l…

@MarkAwt @ScienceMagazine @NaefLab @lollotala MidJourney, good eye! ;)

@TebogCirdec @ScienceMagazine @NaefLab @lollotala Love the graphic, is it MidJourney or another AI?

Excited to share the publication of our new paper "Sex-dimorphic and age-dependent organization of 24-hour gene expression rhythms in humans" in @ScienceMagazine by @NaefLab and @lollotala #circadian #gtex #aging #circadianmedicine science.org/doi/10.1126/sc…

How do our internal 24h #rhythms change across sex and age? @lollotala and @TebogCirdec’s paper is now out in @ScienceMagazine. Congrats to everyone for this stimulating project! science.org/doi/10.1126/sc… #circadian #gtex #aging