Tiago C. Luis

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Tiago C. Luis

Tiago C. Luis

@TiagoCLuis

Group leader @imperialcollege. We investigate how blood stem cells are regulated by their microenvironment in stress and malignant hematopoiesis

London, England Katılım Mayıs 2018
408 Takip Edilen769 Takipçiler
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Tiago C. Luis
Tiago C. Luis@TiagoCLuis·
1/5 Our paper is out today @NatureComms. We report a new feedback mechanism by which, in response to platelet depletion, IL-1 secreted by activated platelets signals through Lepr+ niche cells to activate HSCs and restore homeostasis. @MRC_WIMM, @Karolinskainst, @ImperialImmuno.
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Claudia Ribeiro de Almeida
Claudia Ribeiro de Almeida@cribdealmeida·
Our new manuscript (my first as senior author 🎉). We found that the RNA helicase DDX1 controls germinal centre B-cell maturation through its role in tRNA splicing. If you like the work, consider joining us @BabrahamInst 👉babrahaminstitute.livevacancies.co.uk/#/job/details/…
bioRxiv Immunology@biorxiv_immuno

RNA helicase DDX1 regulates germinal centre selection and affinity maturation by promoting tRNA ligase activity biorxiv.org/cgi/content/sh… #biorxiv_immuno

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Isabel Beerman
Isabel Beerman@BeermanHSCaging·
Congratulations to @hagayanay a fantastic postdoc on the job market: showed HSC divisional history is tracked by DNA methylation and correlates with function. Also beautifully resolves an outstanding question regarding DNA damage and HSC aging rdcu.be/dW3sC
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Kiran Batta
Kiran Batta@Kiran_Batta·
In this study we show, akin to mutations in TP53 gene, its expression levels also could have prognostic significance in TP53 wild type CMML patients. Fantastic work by @Wang_Yu_Hung
Yu-Hung Wang@Wang_Yu_Hung

Delighted to share our latest story!📰 Prognostic and therapeutic implications of #TP53 expression in chronic myelomonocytic leukemia #CMML nature.com/articles/s4140… 🧵 #MDSsm #MPNsm @BloodCancerJnl 🙏 @anjecayu @Kiran_Batta @dwiseman78 @CRUK_MI @UoM_DCS #NTUH @oncodaily

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Alessandra Ferrelli
Alessandra Ferrelli@Ale_Ferrelli_·
Yesterday I defended my PhD Thesis!!👩🏻‍🔬 🧬 🧫 Huge thanks to my examiners @AdamMead_Oxford and @TiagoCLuis for the really inspiring discussion! I can’t thank enough my supervisors, Dominique Bonnet and @KordastiL, for the support during these intense 4 years of PhD!
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Prof Louise Purton
Prof Louise Purton@purton_louise·
Of all the obituaries being currently prepared for Connie Eaves (incl one by @scienceadvocacy & myself), this is one you should definitely read👇🏻. Straight from the ♥️ by her son, a beautiful tribute. Sending love to all members of the Eaves family, we are sharing in your loss ♥️
David Eaves@daeaves

My mom passed a few days ago. There will likely be pieces written about her work, but I wanted to write something that got to the core of who she was. I hope those who knew her see her in it. And those who didn't get a chance to see her. Love to all. eaves.ca/2024/03/10/con…

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Martin Turner
Martin Turner@MartT_babraham·
To feed applied science by starving basic science is like economising on the foundations of a building so that it may be built higher. It is only a matter of time before the whole edifice crumbles. — Sir George Porter 1986
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Anita Scoones
Anita Scoones@AnitaScoonesPhd·
Thrilled to share that I've successfully passed my PhD defense @EI_single_cell 🥳👩‍🎓 Grateful for the support of my advisors @whatchamacaulay @WHaerty, friends + family on this academic journey. 4 years, 94K words, 336 pages, and countless hours in the lab later... I'm #PhDone 🥹
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Tiago C. Luis
Tiago C. Luis@TiagoCLuis·
5/5 Thanks to all involved on a great teamwork, and to all our collaborators.
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Tiago C. Luis
Tiago C. Luis@TiagoCLuis·
4/5 IL-1 signaling in Lepr+ perivascular niche cells is critical for the activation of HSCs proliferation.
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Tiago C. Luis
Tiago C. Luis@TiagoCLuis·
1/5 Our paper is out today @NatureComms. We report a new feedback mechanism by which, in response to platelet depletion, IL-1 secreted by activated platelets signals through Lepr+ niche cells to activate HSCs and restore homeostasis. @MRC_WIMM, @Karolinskainst, @ImperialImmuno.
Tiago C. Luis tweet media
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Keşfet

@BabrahamInst @mganuza1981 @LeukemiaJnl @LeukUK @The_MRC @BeermanHSCaging @hagayanay @ImperialImmuno