Debbie Toiber

Why'd you have to go and make things so complicated? Simplicity as a Lens: A New Way to Model Brain Aging. biorxiv.org/content/10.648… our latest preprint! #AgingResearch #Neuroscience #Alzheimers #SIRT6 #biotech

Congratulations to Yuval, the leading author, and all our collaborators: Dmitrii Smirnov, Songchen Yang, Daniel Stein, Zeev Slobodnik, @EremenkoEkater2 Shai Kaluski-Kopach, Monica Einav, and Ekaterina Khrameeva

Congratulations to Yuval, the leading author, and all our collaborators: Dmitrii Smirnov, Songchen Yang, Daniel Stein, Zeev Slobodnik, @EremenkoEkater2 Shai Kaluski-Kopach, Monica Einav, and Ekaterina Khrameeva

Why'd you have to go and make things so complicated? Simplicity as a Lens: A New Way to Model Brain Aging. biorxiv.org/content/10.648… See our latest preprint! #AgingResearch #Neuroscience #Alzheimers #SIRT6 #BioTech

SIRT6 Regulates Protein Synthesis and Folding Through Nucleolar Remodeling - Stein - 2026 - Aging Cell - Wiley Online Library onlinelibrary.wiley.com/doi/10.1111/ac…

Genluminati follows a group of young scientists who invent a DNA-based religion as a cynical experiment—only to lose control of it when belief spreads, and a prophet emerges. Did the concept begin as #satire for you, or did you always see it turning dark? wp.me/p3cyvH-LYH?utm…

Check out this book recommendation from Literary_Titan: bookbub.com/reviews/203292… via @Bookbub

🟠 For the full article>> nature.com/articles/s4146…

This positions SIRT6 as a critical, upstream drug target for combating neurodegenerative pathology. Amazing work by Shai Kaluski-Kopatch, and collaborators

Crucially, we show that this damage isn't permanent. By inhibiting the enzyme TDO2 in our SIRT6 knockout fly model, we were able to significantly reverse both neuromotor decline and vacuolar formation, indicating a powerful therapeutic window.

SIRT6 decline throws Off Mood, Sleep, and Cognition. rdcu.be/eTvJj Tryptophan byproducts build proteins, NAD+, and neurotransmitters (serotonin and melatonin). Yet, in aging and neurological disease, this balance is lost, leading to impaired mood, learning, and sleep.

@BarakRotblat just in case someone wants to join: amazon.com/dp/B0FWHSYMSM

what am I up to? reading @ToiberDebbie 's new book of course

@BarakRotblat Are you now a believer?

@CharlesMBrenner 🤷‍♀️😁

what could go wrong?

They turn it into a social experiment, testing people’s faith. The book explores their lives as PhD students doing research and as the masterminds behind a new religion, delving into moral and ethical dilemmas when things spiral out of control. Paperback lnkd.in/dUeyR9Mx

GENLUMINATI is now available! In this work of fiction, a group of university friends studying biology becomes obsessed with the idea of creating a religion based on “reading your own genome to achieve enlightenment.” Kindle lnkd.in/dBgqFPBm

@TwoSenzuBeans @ToiberDebbie @BarakRotblat @bengurionu Link to the episode on Spotify open.spotify.com/episode/2brghk…