@SigmaAldrich #SigmaAldrichChocolate Pipettes and beakers, flasks aglow,
Sigma-Aldrich makes research flow!
From buffers to media, pure and bright,
Science and love both shine tonight!
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Trang Nguyen
123 posts
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It was an honor to present our work on targeting lipid metabolism in #BrainTumors at #SNO2024. Deeply grateful to my lab members for their incredible hard work and talent. @MGH_RI @MGHNeurology @MGHNeuroOnc
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Thank you @TheVFoundation for your support of our work towards understanding treatment resistance in glioblastoma!
USC Brain Tumor Center (uscbtc)@USCBTC
The V Scholar Grant is a 600K award over 3 years. This grant is a highly competitive national foundation grant that supports young tenure-track faculty early in their cancer research careers by funding projects that are either laboratory-based fundamental research or translational research. Dr. Modrek attributes the success of his lab to the collaborative support of multiple departments. Dr. Eric Chang, Chair of the Department of Radiation Oncology, and Dr. Caryn Lerman, Director of the Norris Comprehensive Cancer Center, have provided essential guidance and resources. Dr. Modrek's career development has greatly benefited from the mentorship and support of Dr. David Tran, Professor in the Department of Neurosurgery, and Dr. Yali Dou, Associate Director for Basic Science at the Norris Comprehensive Cancer Center. This collective effort underscores the interdisciplinary collaboration that drives the lab's progress. #braincancerresearch #glioblastoma #gbm
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Very happy to see my main project from residency @ColumbiaNeuro finally out! Cool story on mitochondrial #metabolic vulnerabilities and #ferroptosis linked to #GBM cell states. So grateful for the support from Jeffrey Bruce @PCanoll @psimslab @bstockwell @kitaj_angio and others
The EMBO Journal@embojournal
A cell state-specific metabolic vulnerability to GPX4-dependent ferroptosis in glioblastoma @psimslab @PCanoll @Columbia et al find quiescent astrocyte-like glioma cells show abnormal energy metabolism, sensitizing them to ferroptosis-inducing drugs embopress.org/doi/full/10.10…
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@MateiBanu @MikeArgenziano @ColinSperring @FereshtehZand @LarionMioara @NREFORG @NIHFunding Congratulations! Thanks for having me in this wonderful project!
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With lots of hard work from @MikeArgenziano Thanassis Dovas @TrangNguyenBio @ColinSperring @FereshtehZand @LarionMioara and support from @NREFORG and @NIHFunding. We develop a new mouse model to study metabolism in the elusive astrocytic-like glioma cell state
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Glad to announce the publication of our new article, "Methylation profiling of plasma cell-free DNA in pediatric brain tumor patients," which was a collaboration between our brain tumor bank and @Lurieneurosurg and funded by the Charlie Teo Foundation
link.springer.com/article/10.100…
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Thrilled to have joined @TucsonVA @UAZMedTucson @UAZHealth as Asst Prof of Neurosurgery. Looking forward to serving those that have risked their lives for our country & expanding treatment options for devastating neurological tumors. @NSTumorSection #HuntoonLabComing
Tucson, AZ 🇺🇸 English
Glad to see this work from our lymphoma genome project published in Nature Communications. Some really nice data cross functional data from our computational, lab and translational groups in this project.
nature.com/articles/s4146…
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It is an absolute honor to receive this Game-Changer grant- many thanks to @chadtough for funding our research!!! We look forward to developing a novel immunometabolic therapy and imaging strategy for diffuse midline gliomas @UCSFimaging
ChadTough Defeat DIPG Foundation@chadtough
GAME-CHANGER GRANT: Dr. Pavithra Viswanath, University of California, San Francisco (Co-funded by the Violet Foundation)
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I had to pinch myself to be sure I wasn’t dreaming. Two R01 scores - 1 percentile (grant on mutant IDH gliomas) and 3 percentile (diffuse midline glioma)! Wouldn’t have been possible without my wonderful lab, co-investigators (@CarlKoschmann) & department support (@UCSFimaging).
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Just out today, great review by our team on immunotherapy for pediatric low-grade gliomas.
link.springer.com/article/10.100…
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Delighted to contribute to a Frontotemporal Dementia study led by Dr. Gunnar Hargus, published in Cell Stem Cell. Lowering OPN levels led to enhanced engraftment and decreased microglial infiltration, highlighting OPN as a promising target for FTD therapy.
pubmed.ncbi.nlm.nih.gov/38626772/
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@BadRlab Thank you Christian! The underlying mechanism is involved to the integrated stress response with increasing of ATF4.
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Unveiling drug combination therapies for glioblastoma: Demistat (CPI-613) and Navitoclax (ABT-263), with potential applications in other cancer types. Delve into the underlying mechanism of this treatment synergy in my latest publication in JCI Insight.
insight.jci.org/articles/view/…
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@castro2355_mg Yes it is a wonderful event to inspire science for young and talented generation.
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Honored to inspire a love for science at the New Jersey Governor's STEM Scholars event at Bristol Myers Squibb. It unites talented high school and college students dedicated to shaping the state's STEM future. Apply here: lnkd.in/g_NBtFUE #STEM #NJGovernorsScholars
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Very excited to share new work from the lab dissecting mechanisms of liver-metastatic organotropism in melanoma and other cancers. Huge congrats to fearless post-doc @meri_rogava (on the job market!) who led this multi-year study! Below a brief summary...
nature.com/articles/s4301…
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