VOLUME-CHASERS

@OscarJMitchell @OhioHealth @BPTHOSP @LaheyHospital #discoverynetworkwin Team Effort!

Dr Katie Nault, @jonsevransky @MichelleNgGong @tchen383 @gsmartinmd @EinsteinMed @MontefioreNYC @YaleMed @MountSinaiNYC @umichmedicine @OHSUSOM @BrighamWomens @ucincinnati @ClevelandClinic @IntermtnMedCtr @wakeforestmed @TrumanMedKC

Thank you so much for all the participating sites to answer an important question on shock resuscitation. We aimed to describe what usual care really is when managing shock! journals.lww.com/ccmjournal/Abs… @SlurpeeRx @kianoushbk @NidaQadirMD @ChuckCairns

@iwashyna It’s all about THE TEAM!

⁦@VOLUME_CHASER⁩ has so much productive work at ats this year!!@tchen383 ⁦@SlurpeeRx⁩ #ATS2019 ⁦@SCCM⁩ #Discovery ⁦@EinsteinMed⁩

Delayed vasopressors in septic shock= higher mortality. Great job @dch1309 representing @LoyolaHealth at #ATS2019! 🙌@JaiminiP17 @Dalila_Masic

1639 patients from 34 sites, in 4 months!!! @sccm @ATSCritCare @MichelleNgGong @jonsevransky @JoeTonnaMD @SlurpeeRx

Thank you to all the participating sites! Top 5 enrolling: Mayo, UCLA, UAriazona, Mt Sinai NY, and UMichigan! @kianoushbk @NidaQadirMD @ChuckCairns Drs Mathews and Park! and 34 participating sites

motivated clinicians committed to icu recovery & #SCCM #THRIVE2019 were important enablers to innovation in this area ⁦@CAIROrg⁩ #ATS2019

Decision for fluid and vasopressor in shock: arbitrary (think aloud study by Dr Aboodi) #myicucrew

Critical care ultrasound as the most commonly use method of physiologic assessment in shock is still only performed on 31% of the patient in our cohort. (CVP 13%)

Ready to present at RAPID: Dallas Ballroom (Omni) @SlurpeeRx @tchen383

Important finding from @VOLUME_CHASER is that timing of vasopressor dosing makes a difference: early high/later low has lower mortality than early low/later high #SCCMDiscovery #ATS2019 @ogi_gajic @jonsevransky @MichelleNgGong #sepsis #shock

Enrolling 1600+ patients into @VOLUME_CHASER #shock study built from #SCCMDiscovery support across 34 sites. @MayoPCCM @UCLA @UArizonaScience @UMich and 30 more! #ATS2019

Unintended Consequences; Fluid Resuscitation Worsens Shock in an Ovine Model of Endotoxemia | American Journal of Respiratory and Critical Care Medicine | Articles in Press atsjournals.org/doi/abs/10.116…

"Because some evidence indicates that a sustained positive fluid balance during ICU stay is harmful (33–37), fluid administration beyond initial resuscitation requires careful assessment of the likelihood that the patient remains fluid responsive." journals.lww.com/ccmjournal/Ful…