Vanderbilt Molecular Physiology & Biophysics

@GoogleDeepMind released the code behind #AlphaFold3. “The model and weights being released are of huge importance,” @stephanie_mul of @VanderbiltMPB @VanderbiltU said in this @ScienceMagazine article. Read more 👉 science.org/content/articl…

📖 New findings by @VanderbiltMPB @amandacambraia_ @MattACottam1 @deanlab8 in @NatureComms! Caloric restriction improves #insulin sensitivity and boosts pancreatic beta cell longevity in mice, supporting glucose balance and mitochondrial #health. nature.com/articles/s4146…

🧬 Using cryoEM, DEER spectroscopy, and computational analysis, @Mchaourablab @Karakas_Lab @VanderbiltMPB researchers have uncovered a unique interplay between ATP and cargo binding—key to understanding processes like antimicrobial resistance. @NatureComms nature.com/articles/s4146…

Proud of @jwmyers_ for putting together this pre-print! We're grateful to all our collaborators and to @VanderbiltMPB for supporting our studies on the role of purines in physiology. Most importantly, thanks to all the Zaganjor lab members for teaching me something new every day!

Our new article is in press! 🥳🥳 Defining unique structural features in the MAFA and MAFB transcription factors that control Insulin gene activity jbc.org/article/S0021-… @VUBasicSciences @VanderbiltMPB @VUMC_Medicine @DeptVetAffairs @vumcdiabetes

🏆 Congratulations to Danielle Dean, @VanderbiltMPB assistant professor, for receiving Robert L. Sorenson Young Investigator Award from the Midwest Islet Club in recognition of her research excellence in the field of islet research! Read more 👉 news.vumc.org/2024/10/16/dan…

We had a successful Halloween party yesterday! Thank you to everybody who showed up. Our group costume winners were the @AtHinton lab dressed up as Dr. Hinton himself @phdgprotein86, and little Rosie dressed as a horse @MikeSchleh! 👻 🎃 until next year!

Interruption of glucagon signaling augments islet non-alpha cell proli... sciencedirect.com/science/articl… We highlight intriguing biology about the response of delta cells to interrupted glucagon action @deanlab8 Wenbiao Chen @powersac_TN @VanderbiltMPB @VUMC_Medicine @vumcdiabetes

Join us for the annual MPB Halloween party this Thursday at 3:30 pm! Don’t forget to wear your costume 👻

Join us next Thursday as we kick off the MPB guest lecture series with Dr. Calabrese, who will be sharing his research on gene silencing with long noncoding RNAs!

Cyrus C Martin et al. @VanderbiltMPB show that both glucocorticoid levels and multiple differences in the relative activity of eight transcriptional enhancers between mice and humans likely contribute to differential #G6PC2 expression 🐁🧍‍♂️ Read the study ➡️doi.org/10.1530/JME-24…

Fantastic talk today by @TheBurro34 on the mechanisms for GLP-1R agonist-induced weight loss! So much still to be learned in this field!

Congratulations to @TheyCallMeJujuB on successfully defending her thesis a couple of weeks ago! We are forever grateful for the impact you made on the Vanderbilt and MPB community during your time here. We wish you the best of luck during your postdoc at The Ohio State 🥳🎉🙌🏼

Our first MPB graduate student social hour of the academic year is TODAY at 4 pm! We will see you there.

Outstanding seminar today ⁦@WatermanHannah⁩! Super interesting physiological studies about the second meal phenomenon 🤩 Great job 🙌🏻 ⁦@VanderbiltMPB⁩

“A little bit of fever is good, but a lot of fever is bad,” says senior study author @JeffRathmell, a professor of @VanderbiltMPB.

Katie Coate, assistant professor of @VanderbiltMPB has some advice for her younger self: “The path to success will be paved with detours, challenges, and apparent setbacks... It is beneficial to view setbacks as opportunities to learn and grow.” news.vanderbilt.edu/2024/09/16/new…

Delighted to report that I will open my lab @VUMC_Medicine in the Division of Gastroenterology, Hepatology, & Nutrition this Fall. I especially want to thank the many mentors, colleagues, & friends who guided me along the way. @VanderbiltMPB @MouseCentral @MizzouNEPRes

#KiraboLab #postdoc @MDemirc1 is giving a lecture on #tissue #sodium and #salt sensitive #Hypertension on September 30th @VanderbiltMPB!

We are hiring! In partnership with @VanderbiltMPB, we invite applications for a senior or mid-career faculty position in areas related to substance use disorder. This is an excellent opportunity to do science in an amazing environment. jobs.sciencecareers.org/job/662480/fac…