wasim

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wasim

wasim

@Wasim1846

Medical oncologist , love Arsenal, ⚽⚽ and travelling

multan Katılım Ocak 2019
1.4K Takip Edilen77 Takipçiler
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Arsenal
Arsenal@Arsenal·
What a photo 😮‍💨
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MV Chandrakanth
MV Chandrakanth@ChandrakanthMv·
“Are we treating biology… or ovaries?” RxPONDER showed chemotherapy benefit in premenopausal node-positive HR+/HER2− disease. OPTIMA now adds an important layer to the discussion: Could optimized endocrine therapy + OFS explain part of that benefit in genomically favorable tumors? A very important evolving conversation in modern breast oncology: • biology vs anatomy • chemotherapy vs endocrine optimization • personalization vs overtreatment Especially relevant for premenopausal node-positive patients. #BreastCancer #Oncology #ASCO2026 #RxPONDER #OPTIMA #HRPositive #BreastOncology #MedEd #MVOnco
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MV Chandrakanth
MV Chandrakanth@ChandrakanthMv·
• Common antihistamines may influence immunotherapy duration • H1 antihistamine users had longer IO exposure (9.9 vs 7.9 cycles) • Signal appeared strongest with pembrolizumab • Retrospective institutional analysis — hypothesis generating only • Interesting biologic concept needing prospective validation #ASCO2026 #Immunotherapy #CheckpointInhibitors #Pembrolizumab #Oncology #CancerResearch #LungCancer #MedTwitter #OncTwitter #MVOnco
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Dr Rishabh Jain
Dr Rishabh Jain@DrRishabhOnco·
#ASCO26 7 years later… the median PFS with lorlatinib is STILL not reached in advanced ALK+ NSCLC. CROWN continues to deliver one of the most durable targeted therapy signals ever seen in solid tumors. 🧬 CROWN Trial Lorlatinib vs Crizotinib 1L advanced ALK+ NSCLC 📌 Key results: • Median PFS: NR vs 9.1 mo • HR 0.19 • 7-year PFS: 55% vs 3% • No new intracranial progression after 30 months on lorlatinib 🧠 Most striking finding: Patients progression-free at 24 months had a 79% chance of remaining progression-free at year 7. 44% of patients are STILL on lorlatinib at 7 years. Despite higher grade 3/4 AEs (77%), discontinuation due to TRAEs remained low: • 5% lorlatinib • 6% crizotinib This is no longer just “disease control.” For many ALK+ patients, this is beginning to resemble long-term functional remission. 📖 Full abstract in comment ⬇️ #OncoTwitter #MedTwitter #LungCancer #NSCLC #ALK @asco @myesmo @esmo_open @OncoAlert @larvol
Dr Rishabh Jain tweet media
Dr Rishabh Jain@DrRishabhOnco

🫁 THE 10 MOST IMPORTANT LUNG CANCER TRIALS OF #ASCO26 🎯 TARGETED THERAPY MOVES EARLIER 1️⃣ LIBRETTO-432 (LBA3) Adjuvant selpercatinib in resected RET+ NSCLC Precision medicine officially enters curative-intent RET disease. 2️⃣ NeoADAURA Neoadjuvant osimertinib ± chemotherapy in EGFR-mutant NSCLC Targeted therapy keeps moving earlier. 3️⃣ CROWN 7-Year Update Lorlatinib vs crizotinib in ALK+ NSCLC Are we finally seeing a true survival plateau? 4️⃣ MARIPOSA Updated OS Amivantamab + lazertinib vs osimertinib The efficacy vs toxicity debate continues. 5️⃣ Beamion LUNG-1 CNS Cohort Zongertinib in HER2-mutant NSCLC Critical intracranial activity data. 🧬 FRONTLINE PRECISION EXPANSION 6️⃣ SUNVOZERTINIB 1L Frontline uncommon EGFR-mutant NSCLC A huge unmet-need population. 7️⃣ Olomorasib 1L Cohort Second-generation KRAS G12C inhibition moves upfront KRAS continues evolving rapidly. 🔥 IMMUNOLOGY & BISPECIFICS 8️⃣ HARMONi-6 (LBA4) Ivonescimab + chemo vs tislelizumab + chemo PD-1/VEGF bispecifics enter frontline squamous NSCLC. 9️⃣ DeLLphi-312 Tarlatamab in 1L ES-SCLC Potentially practice-changing if positive. 🔟 IMforte Subtype Analysis Can molecular SCLC subtypes finally guide maintenance therapy? Which thoracic abstract are you watching most closely? 👀 #LungCancer #LCSM #OncTwitter #MedTwitter #ASCO26 @ASCO @IASLC @myesmo @esmo_open @OncoAlert

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Highbury49
Highbury49@49Highbury49·
No caption needed❤️
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Premier League
Premier League@premierleague·
10 years on, back in @Arsenal red, Premier League champion ❤️
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Fabrizio Romano
Fabrizio Romano@FabrizioRomano·
❤️🤍🏆 Arsenal lift Premier League trophy after winning the title 2025/26! ✨
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Arsenal
Arsenal@Arsenal·
FULL-TIME ON A SPECIAL PREMIER LEAGUE SEASON ❤️
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Arsenal
Arsenal@Arsenal·
LIFT IT UP ©️
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Arsenal
Arsenal@Arsenal·
Bottle this feeling 🍾
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Dr Rupam Manna MD
Dr Rupam Manna MD@DrRupamOncology·
🚨 Malignant Spinal Cord Compression (MSCC) is an ONCOLOGIC EMERGENCY. New back pain in a cancer patient should NEVER be ignored. Early recognition + rapid intervention can preserve mobility, continence, and quality of life. ⚡ Key steps: ✅ Start dexamethasone immediately ✅ Urgent MRI whole spine ✅ Assess spinal stability ✅ Radiotherapy or surgery based on disease biology & instability ⏳ Time lost = neurons lost. 🧠 Clinical pearls: • Pain often precedes weakness • Thoracic spine is most commonly involved • Ambulatory status predicts outcome • Surgery + RT improves functional outcomes in selected patients #Oncology #MedicalOncology #MSCC #SpinalCordCompression #CancerEmergency #RadiationOncology #Neurosurgery #MetastaticCancer #PalliativeCare #CancerEducation #OncoTwitter #MedTwitter #DrRupamManna #CancerConceptsExplained
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AFTV
AFTV@AFTVMedia·
𝐅𝐈𝐍𝐀𝐋𝐋𝐘!! Arsenal’s name is engraved on the Premier League trophy once again! 🏆️
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Premier League
Premier League@premierleague·
Dressed in @Arsenal red again. ❤️‍🔥
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Premier League
Premier League@premierleague·
It happened.
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Premier League
Premier League@premierleague·
The wait is over. @Arsenal are Premier League champions.
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Sky Sports Premier League
Sky Sports Premier League@SkySportsPL·
ARSENAL ARE THE 2025/26 PREMIER LEAGUE CHAMPIONS! 🏆🔴
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Arsenal
Arsenal@Arsenal·
We did it, together.
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