Xi Chen

We are pleased to welcome neuronal cell biologist Dr. Melissa Hoyer as an assistant professor in our Department of Neurodegenerative Science. Her innovative research aims to prevent neurodegenerative disorders such as Parkinson’s disease. vai.org/article/van-an…

Our new microglia morphology pipeline tool is officially published in eneuro! eneuro.org/content/11/7/E…

@UCSF @UF 📢 Congratulations to 2024 Launch awardee, Dr. Rebecca Wallings, whose project focuses investigating the effects of LRRK2 mutations in immune exhaustion. Dr. Wallings is mentored by @MaluTansey at @UF.

Congrats to former Postdoc Fellows Madalynn Erb and Xi Chen (@XiChen7889) @MooreLabVAI for their paper showing how adult-onset deletion of ATP13A2 in mice provides a greatly improved model of studying PD caused by familial ATP13A2 mutations. Great work! #Ack1" target="_blank" rel="nofollow noopener">nature.com/articles/s4153…

That kick from Michael J Fox into the crescendo of Fix You 👌🏻 #ColdplayGlastonbury

However cynical and hard bitten you are, impossible not to feel something joyful when Coldplay plays with Michael J Fox at Glastonbury

So lucky to share Science in the most beautiful of places ☀️

@RebeccaWallings @ParkinsonDotOrg SUPERSTAR! Many congratulations💙

I am so excited to finally share that I have been awarded the @ParkinsonDotOrg LAUNCH award ✨️ my future independent research program aims to extend my findings of immune cell exhaustion (biorxiv.org/content/10.110…) and try to understand how this may lead to Parkinson's 1/5

The Biennial International LRRK2 Meeting 2024 is currently underway in sunny Crete! We've enjoyed the outstanding presentations and exceptional networking opportunities so far. We look forward to what the next two days bring! #LRRK2_2024 #BiochemEvent

@NeuroWoodworks So sorry to hear that you are going through this right now. Dark D is so insidious. I recently lost my first cousin to it and we are still struggling with this loss. She was one of the bubbliest and most optimistic souls I know…. Keep on fighting! H.O.P.E.= Hold On, Pain Ends

This is my lovely wife, a beautiful soul. As much as I could, I tried to keep her afloat. Today however, depression crushed her so much that she had to be admitted to the hospital. So here I am, alone in bed, again. My four daughters try to cope the best they can and I try to find the strength to work after hours in my workshop to pay the medical bills. I don't allow myself to complain too much because some people go through way worse. But man it sucks right now. The hardest part is the uncertainty, not knowing if someday the dark D will be so strong it will take her life and she will be gone forever. I love her so much. She is the one for me. I can't imagine growing old without her. Our plan has been to sell our house and most of our possessions, once our 4 girls are all out of the nest. Then we would spend the last years of our time on Earth living a simpler life, closer to nature. But today I wonder, who knows if this will ever be a reality? Let's just hope we will find a treatment, a way for her to break that bleak cycle... 🙁 Fuck.

Super excited and out today: Tagless LysoIP method for molecular profiling of lysosomal content in clinical samples biorxiv.org/content/10.110…

Happy Mother’s Day ❤️

Happy 98th birthday to broadcasting icon and one of the world's foremost advocates for nature, Sir David Attenborough FRS. bit.ly/3LNp2yf

Ambassador Applications Now Open for Parkinson and Science Ambassadors for #wpc2026. If you've attended a past Congress and passionate about raising awareness about #Parkinsons, consider applying here: worldpdcoalition.org/page/2026Ambas…

🔬👩‍🔬 Exciting news! I'll soon start my lab @VAInstitute to research molecular mechanisms in Neurodegenerative diseases. 🧠💡 Now recruiting postdocs to join our dynamic research team! Email me if you're interested! #Postdoc #CryoEM #Neuroscience #ResearchOpportunity

We are thrilled to be holding the 7th World Parkinson Congress in Phoenix, Arizona, USA May 24-27, 2026. See You in Phoenix! #wpc2026 Learn more at wpc2026.org @Pahwa_KHSPD @AliceNiewboer @JKordower @MaluTansey @Eli_in_Brooklyn #Parkinsons

I wrote this short blurb about Michael J Fox (@realmikefox) for the annual #Time100. This man means a lot to me. And I know he means a lot to you… ⬇️ I know Michael J. Fox. Like, I know him pretty damn well. He’s funny. He’s warm. He’s handsome and intensely smart. He also falls a lot. Not just because he has Parkinson’s. He falls a lot because he’s unafraid to fly. I met Mike 17 years ago. I’ve watched him raise the bar for purpose and passion. It’d be kinda lazy to simply characterize him as the greatest champion of Parkinson’s research on the planet. He’s someone who helped my dad, along with millions of others, feel less alone. It’d be kinda lazy to simply regard him as a movie star who shaped the lives of people all over the planet with a uniquely electric wit and self-aware charm. He’s the sum of these beautiful parts. And so many more. Last year I watched Back to the Future with my 8-year-old daughter. It’s become her favourite film. And for now, that’s enough for me—and her. One more kid from one more generation sees what I saw. I know how lucky I am to call Mike a friend. She still has no idea that I know him. I don’t need to teach my daughter the level of compassion Mike has mastered. Or teach her to tell stories the way Mike tells stories. I need to teach her that it’s OK to fall a lot. It’s the absolute best way to know you’re flying.

Here is a wood carving of the Purkinje #neuron drawn by Cajal more than 100 years ago. It took me a bit more than 30h to make (no automation, using a scroll saw). Oak wood, 20x30 inches. This one is spoken for but I have it listed in the shop (more photos and link in 🧵). #science #art

BREAKING NEWSVE ABOUT ZOOZVE! They named it! As of today, the FIRST EVER QUASI-MOON DISCOVERED IN THE UNIVERSE is officially named ZOOZVE! 🤯 But that's only half the news! Listen to @Radiolab update: link.chtbl.com/radiolab?sid=t… (PS Brian sneakily added my name to the caption😆)

I finally made this piece, "hippocampe neuronal" (neuronal seahorse). 16 #neurons cut out of Padauk, oak, poplar and maple wood. #sciart #neuroX #biology