Biofluids and Transport Group Imperial

In December, we said farewell to Yilin (a.k.a. Engineer Yang). After 3 years of dedicated work, he successfully defended his PhD, developing multiscale computational models of blood flow, drug transport, and thrombolysis for stroke. 🎉 Well done, Dr Yang!

2026 is just around the corner… Another year, same festive spirits — it’s time to wrap up this very fruitful 2025 at the Biofluids and Transport Group! 🎁 We wish everyone a restful holiday and a productive 2026 ahead! Here are some snapshots…👉

Ever wondered how a double-branched TEVAR device responds to the pulsatile blood flow? 🙋‍♂️🙋‍♀️ Our recent study presents a strongly coupled FSI framework for patient-specific simulation of branch deformation, stress distribution at junctions, and post-TEVAR haemodynamics.

Innovators. Problem-solvers. Changemakers.🔥 Big congratulations to our Class of 2025!👏 #AboutYesterday #OurImperial @imperialcollege

In this 4DMR-based fluid-structure interaction study, 5 boundary conditions were specified for simulating both healthy and asc. aneurysm cases: (1) zero-disp. constraints, (2) longitudinal disp., (3) in-plane disp. (4) combined longitudinal and in-plane disp., and (5) rotation.

🫀 Let’s talk about aortic root motion again! Following the previous study, how does the root motion impact biomechanics, especially the wall stress and wall shear stress (WSS) predictions, of aorta? Well… here’s the recent answer we sought: ieeexplore.ieee.org/document/10955…

🎥 Honoured to be featured by @cebcambridge at the University of Cambridge as one of their researchers 😊 Grateful to be part of a community pushing boundaries in science and innovation! ✨️ #chemicalengineering #biomedicalengineering #modellingheartbreak 🫀⚙️

Thank you Professor Declan O’Regan (@DrDeclanORegan) and Professor Ryo Torii for your time and efforts in this examination. 🙌 🔗 Check out Kaihong’s work through his Google Scholar page scholar.google.com/citations?user…

Today, we send big congratulations to Kaihong Wang (@kaihong1996) for a successful PhD defense! Thank you for your outstanding contributions over the past 4 productive years and for advancing the field of cardiovascular biomechanics! Cheers, Dr Wang! 🥂 🍻

🫀Ever wonder how coronary outflow influences aortic valve function? Turns out, it’s a big deal. Our recent research led by @031Nba shows that coronary outflow and non-Newtonian blood properties can significantly alter wall shear stress. Details below⬇️

Built by @031Nba & team, this FSI model of BPAV features the Edwards Magna Ease valve in action! The simulation results demonstrated good overall agreement with the patient's in vivo data. 🙌 Great work, Zhongjie!

🫀💻Just dropped: A fully coupled fluid-structure interaction model for patient-specific analysis of bioprosthetic aortic valve haemodynamics. 🔗 Heads up, and check it out! frontiersin.org/journals/bioen…

Check out more interesting findings in our article! link.springer.com/article/10.100…

The study also highlights that the idealised inlet velocity profiles adopted for CFD can severely underestimate such changes - patient-specific flow information, such as 4D flow MRI, is indispensable for achieving more realistic biomechanical computations.

What are the alterations in hemodynamics and wall mechanics in ascending thoracic aortic aneurysms? A newly published FSI study by Dr Yu Zhu reveals that ATAA exhibit nearly 3× higher wall shear stress, and almost double peak wall stress vs. healthy aortas.

Special thanks to the examiners @shellygryz and @ChoonHwaiYap for your insightful discussions! Check out Zhongjie’s recent research work here: ⬇️ onlinelibrary.wiley.com/doi/abs/10.100… … and of course, more to come!

Congratulations to Zhongjie @031Nba (soon-to-be Dr Yin!) on nailing his PhD viva! His fruitful 4 years on fluid-structure interaction analysis of native and bioprosthetic aortic valves have truly paid off. We stay tuned to see where this success takes you next. Well done!🎉