Our new paper that uses machine learning to generate a suite of novel protein cages has just been published: cell.com/structure/full…
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Yeates Lab
5 posts
Yeates Lab
@Yeates_Lab
Lab twitter account for the Todd Yeates group @UCLA
Katılım Eylül 2022
13 Takip Edilen205 Takipçiler
Our creation of 'ligand-operable cages' -- designed protein cages that disassemble when they bind a specific cellular protein -- has been published: pubs.acs.org/doi/10.1021/ac…
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Our latest work on solving the cryo-EM problem for small therapeutic proteins is finally out.
pnas.org/doi/10.1073/pn…
Congrats to Roger and the lab!
Roger Castells@rcastellsg
I'm thrilled to share our latest work on designing imaging scaffolds to determine the structure of small proteins using cryo-EM! pnas.org/doi/full/10.10…
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‘Rigidified Scaffolds for 3-Angstrom Resolution Cryo-EM of Small Therapeutic Protein Targets’
Congrats @rcastellsg @kylemeador and team!
With our imaging scaffolds, we report a 2.9A structure for a ~19 kDa KRAS protein oncogenic mutant.
biorxiv.org/content/10.110…
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Designing Protease-Triggered Protein Cages
#proteincages #proteases #proteindesign
pubs.acs.org/doi/abs/10.102…
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