Zhang Lab

The master regulator of naive pluripotent has been identified. This TF also plays an important role in ZGA. nature.com/articles/s4155…

Our research is online! We show that while young HSCs are fairly uniform, old HSCs harbor both “old” and “younger” subsets. Reducing the “old” subset alleviates aging phenotypes in old mice! doi.org/10.1038/s41422…

Congratulations to @LiuYiqiong and the team! It's an excellent start of a project with great application potential. biorxiv.org/content/10.110…

This is a great resource for understanding PFC’s functions. Congratulations to Aritra and @Czh32! biorxiv.org/content/10.110…

Check our detailed protocol for eccDNA purification. We finally solved the “Solution A” supply problem after a long discussion with the manufacture. Now, it will be sold as a single reagent to save user’s money. biorxiv.org/content/10.110…

Congratulations @Czh32 and @RenchaoChen ! A very useful pipeline for integrating scRNA-seq and spatial transcriptomics data sets biorxiv.org/content/10.110…

Job Posting- please RT: The Zhang lab @BostonChildrens #HHMI is looking to hire postdocs with interest and expertise in aging, stem cells, mouse preimplantation development, neurobiology, and bioinformatics. Contact yzhang@genetics.med.harvard.edu zhanglab.tch.harvard.edu

Welcome to the lab, Dr. Yuangao Wang from Shanghai!

Congratulations to a fellow #HHMI investigator for winning a Nobel Prize! twitter.com/HHMINEWS/statu…

Are you at #cshlstemcell in NY this week? If so, stop by Dr. Zhang's talk on DNA methylation independent mechanisms for genomic imprinting.

Check out our newest @Nature publication! Maternal H3K27me3 controls DNA methylation-independent #imprinting. dx.doi.org/10.1038/nature…

Hello, world! We are the Zhang Lab of HMS/BCH/HHMI. Check out our updated website at zhanglab.tch.harvard.edu to see what we're up to!