Joel YR

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Joel YR

Joel YR

@YnfaYr

oncólogo médico

Arequipa, Peru Katılım Şubat 2015
322 Takip Edilen116 Takipçiler
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Dra. María Natalia Gandur Quiroga
💫🌟🚨 Top 10 #BreastCancer abstracts for #ASCO26 — selected by our leads and finalized via a Delphi voting process 🗳️🔬 1️⃣ 500 — OPTIMA 2️⃣ LBA1006 — PERSEVERA BC 3️⃣ 507 — KEYNOTE-522 final analysis 4️⃣ LBA1007 — SERENA-6 5️⃣ 502 — LIDERA BC 6️⃣ LBA1000 — ASCENT-04 7️⃣ 501 — NATALEE biomarker analysis 8️⃣ LBA503 — SENOMAC 9️⃣ 1001 — ASCENT-03 🔟 LBA1003 — Izalontamab brengitecan vs physician’s choice chemo (mTNBC) Proud to amplify this faculty effort 🌍🤝 👇 Tags by group in replies. Leads 🚨 @ElisaAgostinett @to_be_elizabeth @WeOncologists Senior Faculty @ErikaHamilton9 @E_de_Azambuja @matteolambe @DrSGraff @hoperugo @BianchiniGP Dr. Bidard @Icro_Meattini Participating AF @Lucarecco @GaiaGriguolo Ping Faculty @aftimosp @double_whammied @stage4kelly @coffeemommy @itsnot_pink @maryam_lustberg @IBCResearch @kevinpunie @nicolobattisti @raalbany @teamoncology @stolaney1 @LoiSher @SirohiBhawna @chemobrainfog @jamecancerdoc @JavierCortesMD @JaniceTNBCmets @Prof_Nadia_H @paspears88 @MammaMiaMagazin @itrisabel
OncoAlert@OncoAlert

🚨 The OncoAlert #BreastCancer faculty’s TOP 10 abstracts for #ASCO26 — selected by our leads and finalized through a Delphi voting process with senior breast cancer experts. 1️⃣ 500 — OPTIMA Test-directed chemotherapy in high-risk ER+/HER2- early BC 2️⃣ LBA1006 — PERSEVERA BC Giredestrant + palbociclib vs letrozole + palbociclib in 1L ER+/HER2- LA/MBC 3️⃣ 507 — KEYNOTE-522 final analysis Perioperative pembrolizumab in high-risk early TNBC 4️⃣ LBA1007 — SERENA-6 1L camizestrant for emergent ESR1 mutations — final PFS2 5️⃣ 502 — LIDERA BC Giredestrant in ER+/HER2- early BC by menopausal status 6️⃣ LBA1000 — ASCENT-04 SG + pembrolizumab vs chemo + pembrolizumab in 1L PD-L1+ mTNBC 7️⃣ 501 — NATALEE biomarker analysis Baseline gene expression and adjuvant ribociclib benefit 8️⃣ LBA503 — SENOMAC Omission of axillary dissection: OS + arm morbidity 9️⃣ 1001 — ASCENT-03 SG vs chemotherapy in 1L mTNBC — PFS2 🔟 LBA1003 Izalontamab brengitecan vs physician’s choice chemo in metastatic TNBC Leads🚨 @ElisaAgostinett @to_be_elizabeth @WeOncologists Senior Faculty @ErikaHamilton9 @E_de_Azambuja @matteolambe @DrSGraff @hoperugo @BianchiniGP Dr. Bidard @Icro_Meattini Participating AF @Lucarecco @GaiaGriguolo Ping Faculty @aftimosp @double_whammied @stage4kelly @coffeemommy @itsnot_pink @maryam_lustberg @IBCResearch @kevinpunie @nicolobattisti @raalbany @teamoncology @stolaney1 @LoiSher @SirohiBhawna @chemobrainfog @jamecancerdoc @JavierCortesMD @JaniceTNBCmets @Prof_Nadia_H @paspears88 @MammaMiaMagazin @itrisabel

Ciudad Autónoma de Buenos Aires, Argentina 🇦🇷 English
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Virginio Gallardo
Virginio Gallardo@virginiog·
IA y aprendizaje Estudios muestran como la IA generativa (GenAI) tiene un enorme potencial en la tutoría personalizada en la educación Muestra la eficacia de los tutores de chatbot de GenAI para guiar y mejorar el aprendizaje de los estudiantes papers.ssrn.com/sol3/papers.cf…
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JAMA Oncology
JAMA Oncology@JAMAOnc·
Local salvage therapies alone for #ProstateCancer recurrence after radiotherapy maintained >75% androgen deprivation therapy–free survival at 2 years with manageable rates of severe adverse events, supporting their use in selected patients. ja.ma/3PB2ojK
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Nieves Martinez Lago MD PhD
Nieves Martinez Lago MD PhD@DraMartinezLago·
🧠📊 dMMR/MSI-H mCRC: mono vs dual IO ✔️ PD-1 monotherapy → ORR ↑ vs CT + G3-4 toxicity ↓ ✔️ Nivo+ipi → ORR ↑ vs PD-1 alone ⚠️ Toxicity ↑ with dual IO, without consistent OS benefit across trials 💡 Personalization remains key in 1L MSI-H mCRC 🔗 doi.org/10.1186/s12885… @OncoAlert
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OncoAlert
OncoAlert@OncoAlert·
🚨 The OncoAlert #BreastCancer faculty’s TOP 10 abstracts for #ASCO26 — selected by our leads and finalized through a Delphi voting process with senior breast cancer experts. 1️⃣ 500 — OPTIMA Test-directed chemotherapy in high-risk ER+/HER2- early BC 2️⃣ LBA1006 — PERSEVERA BC Giredestrant + palbociclib vs letrozole + palbociclib in 1L ER+/HER2- LA/MBC 3️⃣ 507 — KEYNOTE-522 final analysis Perioperative pembrolizumab in high-risk early TNBC 4️⃣ LBA1007 — SERENA-6 1L camizestrant for emergent ESR1 mutations — final PFS2 5️⃣ 502 — LIDERA BC Giredestrant in ER+/HER2- early BC by menopausal status 6️⃣ LBA1000 — ASCENT-04 SG + pembrolizumab vs chemo + pembrolizumab in 1L PD-L1+ mTNBC 7️⃣ 501 — NATALEE biomarker analysis Baseline gene expression and adjuvant ribociclib benefit 8️⃣ LBA503 — SENOMAC Omission of axillary dissection: OS + arm morbidity 9️⃣ 1001 — ASCENT-03 SG vs chemotherapy in 1L mTNBC — PFS2 🔟 LBA1003 Izalontamab brengitecan vs physician’s choice chemo in metastatic TNBC Leads🚨 @ElisaAgostinett @to_be_elizabeth @WeOncologists Senior Faculty @ErikaHamilton9 @E_de_Azambuja @matteolambe @DrSGraff @hoperugo @BianchiniGP Dr. Bidard @Icro_Meattini Participating AF @Lucarecco @GaiaGriguolo Ping Faculty @aftimosp @double_whammied @stage4kelly @coffeemommy @itsnot_pink @maryam_lustberg @IBCResearch @kevinpunie @nicolobattisti @raalbany @teamoncology @stolaney1 @LoiSher @SirohiBhawna @chemobrainfog @jamecancerdoc @JavierCortesMD @JaniceTNBCmets @Prof_Nadia_H @paspears88 @MammaMiaMagazin @itrisabel
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Dr Rishabh Jain
Dr Rishabh Jain@DrRishabhOnco·
Breast cancer surgery is entering its de-escalation era. AGO 2026 just pushed the field another step forward: 🔹 Omit SLNB in selected low-risk cN0 patients 🔹 Prefer TAD over ALND after NACT 🔹 Reserve full axillary dissection mainly for residual macrometastatic disease The axilla is no longer “one-size-fits-all.” Biggest shift? Patients converting from cN+ → ycN0 after neoadjuvant therapy may avoid the morbidity of ALND without compromising regional control. Less lymphedema. Less neuropathy. Less long-term toxicity. More precision. More personalization. The modern breast surgeon is no longer just removing disease. They are actively preserving quality of life. 📖 Full paper in comment ⬇️ #OncoTwitter #MedTwitter #BreastCancer #BreastSurgery @OncoAlert @myesmo @esmo_open @ASCO
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Paolo Tarantino
Paolo Tarantino@PTarantinoMD·
Only few days to #ASCO26. For breast oncologists, this edition will deliver a new promising biomarker to spare unnecessary chemo, informative updates from practice-changing trials across subtypes, and major innovations coming from China. See you in Chicago next week! #bcsm
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Karamvir Yadav
Karamvir Yadav@K_Yadavir·
Could second-event endpoints be the future of immunotherapy trials? Early anti–PD-(L)1 therapy may deliver benefits far beyond first progression. Meta-analysis of 47 RCTs: ✅ Better EFS2/PRFS2/PFS2 ✅ Stronger OS surrogacy than conventional endpoints ✅ Biggest gains in NSCLC & dMMR/MSI-H disease Time to rethink sequencing in immuno-oncology. #oncology #IO #immunotherapy #NSCLC #medtwitter @OncoDailyIO @sitcancer @Erman_Akkus
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MV Chandrakanth
MV Chandrakanth@ChandrakanthMv·
When Kaplan–Meier Curves Fool You 📉 A flat survival tail can look exciting… but sometimes it reflects very few patients remaining under follow-up. The curve alone is never enough. Always check: • Number at risk • Censoring patterns • Follow-up maturity • Late-tail denominator A “long-term survivor plateau” is meaningful only when enough patients are still being observed. One of the most important lessons in interpreting immunotherapy trials. #Oncology #MedEd #Biostatistics #Immunotherapy #ClinicalTrials #KaplanMeier #MVOnco
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Diego A. Díaz-García
Diego A. Díaz-García@diegoadiazg·
🫁 Fixed-dose vs weight-based pembrolizumab in NSCLC. Real-world data showed comparable OS and irAE rates between fixed-dose (200 mg Q3W) and weight-based dosing (2 mg/kg Q3W). Potential cost-saving strategy for underweight patients and resource-limited settings without compromising outcomes. 📖 JCO Oncology Practice DOI 👉🏻 doi.org/10.1200/OP-25-… #CánCare #nsclc #lcsm #immunotherapy
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Dr Rishabh Jain
Dr Rishabh Jain@DrRishabhOnco·
🚨 THE 15 MOST IMPORTANT TRIALS OF #ASCO26 May 29 - June 2 | Chicago Which trial are you watching most closely? 🌟 PLENARY GAME-CHANGERS 1️⃣ PROTEUS Perioperative apalutamide + ADT in high-risk localized prostate cancer 2️⃣ LIBRETTO-432 Adjuvant selpercatinib in RET+ NSCLC 3️⃣ HARMONi-6 Ivonescimab + chemo vs tislelizumab + chemo in squamous NSCLC 4️⃣ RASolute 302 Daraxonrasib (RMC-6236) in metastatic pancreatic cancer 5️⃣ SARC041 Abemaciclib in dedifferentiated liposarcoma ⚡ FRONTLINE & PERIOPERATIVE SHIFTS 6️⃣ KEYNOTE-B15 / EV-304 EV + pembrolizumab vs chemo in MIBC 7️⃣ LITESPARK-022 Pembrolizumab + belzutifan in adjuvant ccRCC 8️⃣ AMBITION Paclitaxel/bevacizumab ± atezolizumab in HR+ breast cancer 9️⃣ NeoADAURA Neoadjuvant osimertinib in EGFR+ NSCLC 🔟 A-DREAM ADT interruption strategies in mCSPC 🧬 PRECISION, ADCs & NEXT-GEN IMMUNOLOGY 1️⃣1️⃣ DESTINY-Breast06 T-DXd expands into HER2-ultralow disease 1️⃣2️⃣ CROWN (7-year update) Lorlatinib durability in ALK+ NSCLC 1️⃣3️⃣ DeLLphi-312 Tarlatamab in frontline SCLC 1️⃣4️⃣ COMMIT Atezolizumab + FOLFOX/Bev in MSI-H mCRC 1️⃣5️⃣ IMvigor011 ctDNA-guided adjuvant atezolizumab in bladder cancer #OncoTwitter #MedTwitter #ASCO26 #CancerResearch @OncoAlert @ASCO @JCOPO_ASCO @OncBrothers
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MV Chandrakanth
MV Chandrakanth@ChandrakanthMv·
ESMO Breast 2026 — key trials at a glance • HER2+ trials • HR+/HER2− trials • TNBC / ADC / Immunotherapy trials Major studies, key results, and clinical take-home messages — all in one quick visual summary. #ESMOBreast2026 #BreastCancer #Oncology #MVOnco
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Dr Rupam Manna MD
Dr Rupam Manna MD@DrRupamOncology·
🚨 EVOLUTION OF ADJUVANT TREATMENT IN GALL BLADDER CANCER (GBC) 📊 One of the most aggressive biliary tract malignancies — high recurrence even after curative surgery. From “Surgery Alone” → Fluoropyrimidines → Gemcitabine combos → Capecitabine standardization (BILCAP era) → now moving toward biomarker-driven & immunotherapy approaches. High-yield timeline, landmark trials (BILCAP, PRODIGE-12, BCAT, SWOG S0809, ABC-02), current global standard, role of RT, molecular targets & future directions — all in one frame. ✅ Current standard: 6 months adjuvant Capecitabine (ASCO | ESMO | NCCN) ✅ When to consider RT ✅ Emerging ctDNA & IO strategies Save this 📌 for tumor boards, wards, DrNB/DM exams & clinic. Cancer Concepts Explained — Dr Rupam Manna Medical Oncologist #GBC #GallBladderCancer #BiliaryTractCancer #AdjuvantTherapy #BILCAP #Oncology #MedEd #MedTwitter #CancerConceptsExplained
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Dr Rupam Manna MD
Dr Rupam Manna MD@DrRupamOncology·
📊 EVOLUTION OF PERIOPERATIVE CHEMOTHERAPY IN GASTRIC CANCER – Landmark Trials That Changed Practice (2026 Update) From Surgery Alone → MAGIC (ECF) → FNCLCC/FFCD → CLASSIC → FLOT4-AIO (current global standard) → ESOPEC superiority → now the Immunotherapy era (MATTERHORN durvalumab + FLOT & more!) High-yield timeline, summary table, key results, why FLOT wins, present-day standard for fit patients & exam pearls for resectable gastric & GEJ adenocarcinoma. Perfect for DM/NEET-SS prep, tumor boards & daily oncology practice. Save it 🔖 | Share it 🔄 | Use it daily 🩺 #GastricCancer #FLOT #MATTERHORN #PerioperativeChemo #Oncology #MedTwitter #NEETSS #OncoEducation Dr Rupam Manna @DrRupamOncology
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Yakup Ergün
Yakup Ergün@dr_yakupergun·
Simultaneous publication with #ESMOBreast26 An excellent de-escalation study: PHERGain-2 study A chemotherapy-free, pathological response-adapted strategy using trastuzumab–pertuzumab and T-DM1 in HER2-positive early breast cancer sciencedirect.com/science?_ob=Ga…
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