Zwicker Group

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Zwicker Group

Zwicker Group

@ZwickerGroup

Theoretical biophysics group @mpids. We study how soft and fluid-like materials are organized in biological organisms and cells. @zwickergroup.bsky.social

Göttingen, Germany Katılım Temmuz 2019
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Zwicker Group
Zwicker Group@ZwickerGroup·
We welcome 🇩🇪Henri Schmidt to our group! 🎉 Henri will work on multicomponent phase separation and graduate with a PhD in a few years. Welcome aboard!
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Ariel Amir
Ariel Amir@Ariel_4321·
Stimulating week, first a Munich conference "Frontiers in Physics", covering topics from black holes to biophysics, then the EMBO meeting in Heidelberg, with lots of great biology. Very grateful to @EMBO for electing me as a new member (image: Asaph Aharoni talking about plants)
Ariel Amir tweet media
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brangwynnelab
brangwynnelab@brangwynnelab·
Honored to be inducted into American Academy of Sciences & Letters - beautiful ceremony @ Library of Congress. A treat to celebrate w scholars I admire including @sapinker @HenryLouisGates Jeffrey Eugenides & Princeton's Torquato Kulkarni Poor Jordan Haykel Ionescu Macedo & Lee
American Academy of Sciences and Letters@AASL_Academy

What a night! During our 2024 investiture ceremony at the Library of Congress last night, a total of 60 people became members of the Academy.

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Zwicker Group retweetledi
Job Boekhoven
Job Boekhoven@BoekhovenLab·
RT appreciated: My lab is recruiting several Ph.D.s and Postdocs excited to build synthetic cells that undergo Darwinian evolution. The backgrounds that we need for include biochemistry, synthetic biology, and systems chemistry. Details: boekhovenlab.com/openings/
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Zwicker Group
Zwicker Group@ZwickerGroup·
Filipe Thewes 🇧🇷 joined our group this week! After a successful PhD with @psollich at @uniGoettingen, he moved up the hill to help us understand multicomponent phase separation. Welcome aboard! 🥳
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Zwicker Group
Zwicker Group@ZwickerGroup·
@ShuLab2010 @WallaceUcsf Our generic reply to this question is that it’s not the right question to ask. Certainly, biology does not care whether we call a cluster a „condensate“. Instead we find it helpful to ask whether describing a cluster as a condensate makes useful predictions!
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Xiaokun Shu
Xiaokun Shu@ShuLab2010·
What is a biomolecular condensate? Is a 100-macromolecule cluster a condensate? How about 50 or even 10? What's the smallest size, the lowest # to form a condensate? How biochemical activity is enhanced in cluster vs condensate? LMK U r interested, share your answers before mine.
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Zwicker Group
Zwicker Group@ZwickerGroup·
The full article at arxiv.org/abs/2409.15599 has many more details and we will explorer the role of charges further. This work started from a short discussion after a Zoom talk by @jerelleaj and was driven by @luochengjie58, Nate Hess, Dilimulati Aierken, and Yicheng Qiang!
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Zwicker Group
Zwicker Group@ZwickerGroup·
Interestingly, the strength of phase separation has only a weak effect on droplet size, which we confirmed with more simulations. Our work shows how charge can control droplet size, e.g., to regulate #condensates inside biological cells.
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Zwicker Group
Zwicker Group@ZwickerGroup·
Happy to announce a preprint by @jerellea’s and our group. 🎉 arxiv.org/abs/2409.15599 shows that #droplet growth is arrested at finite sizes when the phase separating material evokes a net #charge of the droplet. The attached molecular dynamics simulation visualizes this effect
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Zwicker Group
Zwicker Group@ZwickerGroup·
We welcome 🇳🇱 Guido Kusters as a new postdoc in our group! Guido did his PhD in Eindhoven and will work on various topics involving phase separation with us. Welcome aboard! 🎊🎉
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Zwicker Group
Zwicker Group@ZwickerGroup·
It’s amazing to see experimental evidence for a mechanism we conceived about a decade ago! Congratulations to @BoekhovenLab and @WebersGroup – this is surely just the beginning of an exciting scientific journey! 🎉
Job Boekhoven@BoekhovenLab

Frank Jülicher, @ZwickerGroup, Rabea Seyboldt, @HymanLab, @WebersGroup predicted such a size control in a theoretical framework. We have now verified that mechanism for the first time in an experimental system! nature.com/articles/nphys…

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