Alexa Sem

Novel mRNA vaccine prevents and treat C. difficile penntoday.upenn.edu/news/penn-medi…

This work wouldn't have been possible without the dedication and hard work of my co-first author @MGAlameh and our collaborative research team in the @Weissmanlab, @joeyzacks laboratories, and beyond. A huge thank you to all who contributed to this groundbreaking study

We believe this study is a step forward in the ultimate eradication of C. diff and shows the incredible potential of the mRNA-LNP platform in the fight against infectious diseases. Our findings open new avenues for vaccine development against other complex bacterial infections

I’m proud to share our recent publication describing the development of a multivalent mRNA-LNP vaccine for C. difficile that incorporates targets across C. diff’s complex life cycle science.org/doi/10.1126/sc…

Really excited to share our labs first paper published today in @Nature. This work was led by the amazingly talented @Brokaryote, who found that enterococci enhance C. diff fitness and pathogenesis by metabolically remodeling the gut during infection. nature.com/articles/s4158…

Our study on how fungal strain diversity (through specific fungal and host immune factors!) defines host-mycobiota interactions in intestinal #immunity and #IBD is out now @Nature @lixinxunle1 @WeillCornell /#article-info" target="_blank" rel="nofollow noopener">nature.com/articles/s4158…