The Drew Weissman Lab

New article👏One-component ionizable amphiphilic Janus dendrimers as a delivery platform for efficient mRNA vaccine development | Science Advances science.org/doi/10.1126/sc…

Weissman Lab wishes everyone a Happy International Day of Women and Girls in Science! #InternationalDayofWomenandGirlsinScience

"Sooner or later all the people of the world will have to discover a way to live together in peace..." Remembering Martin Luther King Jr., an extraordinary man, who was awarded the 1964 Nobel Peace Prize for his non-violent campaign against racism. He also fought to secure economic justice for people living in poverty. Watch his Nobel Peace Prize speech: bit.ly/3bJCQuc

Cedar fever cure? Researchers developing vaccine for severe allergies @JilianMelamed kxan.com/news/science/c…

📣Today @ 4pm: RNA Collaborative - NCI RNA Biology Initiative & Penn Institute for RNA Innovation, featuring BMB graduate student Rachel Braun “Selective decay of interferon mRNAs controls antiviral immunity and innate memory" us02web.zoom.us/webinar/regist…

A Scientific Pipeline to the Nobel Prize Fueled by Immigrants nytimes.com/2025/12/10/sci…

Check out our latest collaborative work in @Biomaterials_ with @KaraSpillerLab @HannahGeisler_ @WeissmanLab on a new interleukin-4 mRNA lipid nanoparticle macrophage cell therapy to sustain a pro-reparative phenotype in inflammatory injuries! Open access: sciencedirect.com/science/articl…

I talked to @DrPaulOffit, Nobel-winning MRNA inventor @WeissmanLab & CHOP's Charlotte Moser about Philadelphia’s imperiled medical research ecosystem: cityandstatepa.com/policy/2025/10… via @CityAndStatePA @ChildrensPhila @CHOP_Research

Dr. Weissman discussed the role of mRNA-LNP for cancer treatment & autoimmunity He concluded with a call to action: equitable IP access and capacity building for vaccines and therapeutics in LMICs, addressing diseases that disproportionately affect these regions @WeissmanLab

🎉Our newest pre-print is now online on bioRxiv! Anionic lipids modulate mRNA-lipid nanoparticle immunogenicity and confer protection in a mouse model of multiple sclerosis @JilianMelamed @weissmanlab biorxiv.org/content/10.110…

Harnessing mRNA-lipid nanoparticles as innovative therapies for autoimmune diseases dlvr.it/TMYps4 #MTMCD

Robert F. Kennedy Jr announced that the US federal government is terminating US$500 million worth of grants for mRNA vaccine research. We must never, ever, forget that millions are alive today, or in better health, because of this life-saving technology. go.nature.com/3HDCS9n

#ICYMI: Registration is now open for Cores Day on Thursday, September 11th!🥳🎉 @PennMedicine @ChildrensPhila @PennVet @TheWistar -Free registration➡️ tinyurl.com/3bu5pjfd -Event website➡️ tinyurl.com/yc83cmj4

ft. Ningqiang Gong, @DongyoonKim5, @_emilyhan_, @rohan_palanki, @ShiQiangqiang, @Xuexiang_Han, @Lulu_Xuee, @Junchao_online, Christian Figueroa-Espada, @MJMitchell_Lab (@pennbioeng), @MgAlameh, @Rakan_ElMayta, Garima Dwivedi & @WeissmanLab (@PennMedicine) nature.com/articles/s4155…

Calling all BGS alumni - come celebrate 40 years of BGS with us this fall, as we bring together alumni, students, and faculty to revisit where we've been and make new, lasting connections. We can't wait to welcome you back to campus! Register here: pennmed.events.alumniq.com/go/bgs40

Fewer side-effects, more effectiveness. @MJMitchell_Lab's lab redesigned mRNA lipid nanoparticles using olive oil-inspired chemistry. Adding phenol groups reduces inflammation, making mRNA therapies safer & more effective. "It's a win-win," says Mitchell.

RNA chemistry and therapeutics, an exciting and impactful review article in collaboration with Dr. Drew Weissman! @WeissmanLab nature.com/articles/s4157… rdcu.be/ewb32

This week we'll be at the CRS 2025 Annual Meeting & Expo! @CRSScience #CRS2025

Red Ribbon Connect links Penn with HIV/AIDS researchers worldwide bit.ly/4ksSslO