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Antea
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Humans sometimes get educated out of their innate curiosity, or we become too exhausted to live curiously.
Yet curiosity is the flame of all discoveries and innovation. And the light of self discovery and awareness.
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Life at every scale is such an energetic process.
Here is a phagocytic cell, exhibiting what is likely the precursor to animal curiosity, finding and eating invaders.
How much energy does it cost to move about the world with vibrant curiosity?
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The first order effect of exercise is to increase energy flow through the metabolic circuitry of your body, including your mitochondria. The harder you breathe, the more oxygen your mitochondria are consuming.
Predictably, exercising vigorously decreases the risk of all common chronic illnesses, including Type 2 diabetes--a disorder triggered by metabolic oversupply. But the disorder most impacted across the board was dementia. pubmed.ncbi.nlm.nih.gov/41905344/
Based on the comorbidity of Type 2 diabetes with Alzheimer's disease and other dementias, and some other evidence, some have called Alzheimer's disease Type 3 diabetes. This emphasizes the metabolic basis of neurodegeneration.
Not entirely sure about that framing, but seeing dementia (#1) and Type 2 diabetes (#2) at the top of the health disorders most affected by physical activity suggest a shared etiology.
In both cases, exercise intensity (how hard you breathe) seems to carry more weight than volume (how long you exercise).
The sustained health of our brain, body, and mind requires energy flow. Next time you feel out of breath, think about how you're feeding oxygen to your mitochondria, fueling the flow of energy that keeps you alive.
The biological principle behind these effects is captured in the energy resistance principle: martinpicard.substack.com/p/erp
Some thoughts on our transition from genetics to energetics: martinpicard.substack.com/p/from-genetic…
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This morning on The Science and Experience of Energy, we share our experiences and questions that emerged in Nepal.
Join @niroshajmurugan and I on a little adventure to the Himalayas, discovering Buddhist perspectives on the human mind and body.
martinpicard.substack.com/p/spirituality…
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Exercise is good for the brain. But why?
This morning in The Science and Experience of Energy we explore the effects of exercise on brain mitochondrial. And why making more mitochondria might in part be why moving keeps our brain healthy.
martinpicard.substack.com/p/mitochondria…
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Mitochondria and the energy that flows through them is a broad consilience point that integrates several molecular, metabolic, behavioral, and psychological factors.
So it's likely to play an outsized role in brain health, and health in general.
Bedtime Story@BoMiaoFinance
The timing on this is uncanny. Nature Mental Health just published a 4M-person meta-analysis (27 cohorts, 9 countries) — VO2max predicts depression risk -36%, dementia -39%, psychotic disorders -29%. Each 1-MET CRF improvement cuts depression risk by 5%. Your mitochondrial biogenesis work might be the cellular mechanism explaining why the effect is transdiagnostic — BDNF, inflammation suppression, and HPA axis normalization all run through mitochondrial function.
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A mí me sigue fascinando la cantidad de energía discursiva que gastan muchos tuiteros en cosas que ocurren a miles de kilómetros, mientras tienen al lado el drama humano diario de miles de compatriotas y no dicen ni pío. Qué facilidad para la dispersión mental y cuánta hipocresía
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Así participamos en lo que nosotros mismos llamamos la locura del mundo, con nuestra propia incoherencia. Lo de no ver la viga en ojo propio…
Rafael Nieto@RafaelNieto46
A mí me sigue fascinando la cantidad de energía discursiva que gastan muchos tuiteros en cosas que ocurren a miles de kilómetros, mientras tienen al lado el drama humano diario de miles de compatriotas y no dicen ni pío. Qué facilidad para la dispersión mental y cuánta hipocresía
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Ida Rentoul Outhwaite
( Carlton, Australia, 1888 - 1960 )
" El Hada conoce al Sr.Ardilla "
( " Walk me through my Dreams " )
1916 ._
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@MikyMikaela2 @_anteale @literlandweb1 @Atlas_131 Ella la está psicoanálizando. En vez de disfrutar su escritura
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"Hay una especie de tristeza que viene de saber demasiado, de ver el mundo como realmente es. Es la tristeza de entender que la vida no es una gran aventura, sino una serie de pequeños, insignificantes momentos, que el amor no es un cuento de hadas, sino una emoción frágil y fugaz, que la felicidad no es un estado permanente, sino una rara y fugaz vista de algo que nunca podremos sostener. Y en ese entendimiento, hay una profunda soledad, una sensación de estar aislado del mundo, de otras personas, de uno mismo".
"El faro, Virginia Woolf
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@marisamuguer @literlandweb1 @Atlas_131 A mí me da pena que a veces tengamos que sentirnos así, y ganas de recordar a quien así se siente que esa solo es una cara de la realidad. Recordar que hay que aceptarla y dejarla pasar. Todo es parte de la vida y todo sirve.
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@Davcolgar En sentido literal imagino que sí. 😊
Pero yo escucho una metáfora.
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@_anteale Es la realidad en muchos sitios pobres donde cocinan con leña. Me recuerda a algunas regiones de la India y a muchos países africanos.
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Civilization is what happens when man partakes in the creative act of God on a grand scale:
Making gardens out of wilderness, dynasties out of families, monuments out of raw material.
Mark W.@DurhamWASP
“What is civilisation? I don’t know. I can’t define it in abstract terms. But I think I can recognise it when I see it...” Kenneth Clark
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‘We are healthy only to the extent that our ideas are humane.’
Kurt Vonnegut,
Breakfast of Champions
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‘Just keep going. No feeling is final.’
Rainer Maria Rilke
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