

Alina Mikhailova
119 posts

@aaragret
PhD student at the IEB @bornberglab, University of Münster. Evolution of social insects 🪳











New #openaccess #research from @KPopadin & colleagues shows that formation of age-associated deletions in #human #mtDNA is influenced not only by #DNA similarity between breakpoint regions but also by topological proximity bit.ly/3I2uBZB #aging #replication #mitochondria

One important step to uncover a source of mitochondrial mutations: the older the somatic cell/oocyte/organism, the more A>G mutations on a single-stranded heavy chain. We propose that A>G is a hallmark of age-associated oxidative damage. (1/3)







