Bôdi

@LegacySiu 🇧🇷

Guess the national team Level: HARD

Na próxima nem nomeia bando d fdp

@lightningclare You really went ahead and said huh

When you get down to it Megumi is a genius. He's able to figure out exactly how stupid complex CTs like Love Rendezvous work with no intel and pick up subtle face cues. He's done this TWICE already No wonder Gojo saw potential in him. Like Sukuna in terms of deductive ability

#NATO IS GONE

@JeinArtis @Lucca_hf @hourly_shitpost

@Lucca_hf @hourly_shitpost @agugumon

@ThalesLobo_A Skadoosh

vtnc a frase do meu aniversário é de kung fu panda isso é mt lindo

@JeinArtis @spaceboikoma

@spaceboikoma @agugumon

@cornycracker Mané Taylor Swift eu queria ver o baixinho chamando o Drake de pedofilo porra A Minor neles

liguei a tv agora pouco e 24x0? kkkkkkkkkkk taylor swift ta mal

@kanyewest @JeinArtis @Lucca_hf @ollimacsacul

@begninho Eh nisso q dá apostar contra o fluzudo, FAZUÉLI PORRA

@Lucca_hf @JeinArtis @CidadaoInforme @metro_rio

@JeinArtis @CidadaoInforme @metro_rio @agugumon

Um policial a paisana, pediu para um rapaz ceder o lugar para uma senhora, o rapaz esculachou ele, que sacou a arma e mandou ele descer! @metro_rio

@Vinheteiro @JeinArtis @Lucca_hf n vou ver o lord punheteiro falando merda sozinho qnd na frança os desgraçados arranjavam 50 mil motivos p fechar as coisas

O Brasil é o único país do mundo onde fecha os pontos turísticos nos feriados, e abre os museus e as igrejas nos dias úteis, quando não existem turistas. É por essas e outras que este país não tem futuro. Ninguém quer trabalhar.

Thrilled to share our new publication, “Histone mark age of human tissues and cell types,” in Science Advances! TL;DR 🔑 Accuracy: Histone mark ChIP-Seq data can be leveraged to build highly robust age predictors (r > 0.9). 🐕 Interpretation: Top genes are evolutionarily conserved, overlapping with pan-mammalian clocks. ☝️ Single Predictor: One model works across activating and repressive modifications—no conditional needed. 🐍 Open-Source: Models freely available on pyaging. Paper: science.org/doi/epdf/10.11… Code: github.com/rsinghlab/Hist… Our work pays homage to @prof_horvath's 2013 landmark paper on a DNA methylation aging clock. Here, we focus on histone marks, another epigenetic layer. Why bother with histone marks when DNA methylation is cheaper and widespread? Some popular model organisms (e.g., C. elegans, Drosophila) lack meaningful DNA methylation. Moreover, histone marks can be more easily assigned to specific genes and pathways, making biological interpretation more direct. The histone code is also arguably more complex and diverse than DNA methylation. Notably, we discovered certain regions of the genome that simultaneously gain or lose both activating and repressive marks with age. The biological implications remain unclear but it would be interesting to explore whether rejuvenating techniques such as OSK reprogramming can restore such loci to a youthful epigenetic state. Massive thanks to all coauthors, especially Prof. Singh from my alma mater @Brown and the legendary Prof. @prof_horvath. Couldn’t have done it without your guidance! Figures: • 📜 Abstract snippet • 📈 Scatterplot showing cross-validation performance of the pan-histone mark, pan-tissue predictor • 📋 Table of most important protein-coding genes (positive & negative coefficients)

@JeinArtis @Sxmureye Eu aí

@Sxmureye @agugumon

I know she’s lowkey Hitler but she’s so beautiful idc

@Lucca_hf @insaneposes @JeinArtis Eu qnd compro 100 mochilas na amazon so p deixar embaixo d um acento d tgv

@insaneposes @JeinArtis @agugumon Como o francês médio lida com os atrasos da SNCF

I’m glad to finally make public what I built over the last several months! CpG Pretrained Transformer (CpGPT) is a foundation model that is an outstanding tool for everything DNA methylation🧬. It achieves SOTA or near SOTA performance in virtually all the tasks I’ve tested so far. Also happy to have the rising start @rv_sehgal, the clock legend @prof_horvath, and the scGPT father @BoWang87 as coauthors for this incredible project.

@_Walentino @HooddSZN No way you chose that as THE problem with the video 💀

@elonmusk @Lucca_hf os comentarios mais boomercore q tu vai ver

What reason was given for repealing this law?

@JeinArtis @aladsonofoda @ollimacsacul @Lucca_hf

@aladsonofoda @ollimacsacul @Lucca_hf @agugumon