city-investor
23.2K posts

city-investor
@aim_gravy
Full time AIM / US Penny stock trader / investor 10 yrs+. no investment advice given DYOR









Came across this for #NFX #NFX Hantavirus link Nuformix's relevance to Hantavirus lies in the shared pathological mechanism of the NLRP3 inflammasome and the resulting cytokine storm. Research has shown that Hantavirus infection triggers the NLRP3 inflammasome, leading to the excessive release of pro-inflammatory cytokines like IL-1$\beta$, which cause the life-threatening vascular leakage and acute respiratory distress characteristic of Hantavirus Pulmonary Syndrome (HPS). Nuformix’s lead asset, NXP002, is an inhaled formulation of Tranilast, a potent NLRP3 inhibitor. By delivering this anti-inflammatory agent directly to the lungs, NXP002 could theoretically mitigate the "microvascular leak" and severe pulmonary inflammation triggered by the virus. While Nuformix officially targets chronic fibrosis, the ability of their core technology to suppress the specific inflammatory pathways that drive Hantavirus mortality provides a strong scientific "hook" for its potential application in acute viral respiratory crises. Summary of the link between NFX and Hantavirus: The Trigger: Hantavirus activates the NLRP3 inflammasome, causing lung fluid and vascular collapse. The Solution: Nuformix's NXP002 (Tranilast) is a known NLRP3 inhibitor. The Delivery: Because Hantavirus primarily attacks the lungs (in HPS), Nuformix’s inhaled delivery method is ideally suited to treat the site of infection more effectively than traditional oral drugs.


Massive day for me with this very large position at CDL. At one point this was down offside a huge amount. Mentally it was dark. But patience is rewarding us at #CDL How things change very quickly aye. Roll on 1p next week. Perfect week #NCYT also a bag.






