Ali Arafa retweetledi
Author explains the story behind this legendary case report 💡
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Ali Arafa
143 posts
Ali Arafa
@aliarafaa
Postdoc at @UMNews | Passionate about GU Oncology | Royal College of Surgeons alumnus | Interested in proteogenomics and liquid biopsies 🇪🇬🇺🇸
MN Katılım Ocak 2011
655 Takip Edilen452 Takipçiler
Excited to share our prostate cancer proteomics work, initially presented at #ASCO25, is now featured on @VuMedi! Grateful for the chance to share how liquid biopsy biomarkers may help shape the future of personalized therapy. @UMNCancer @MPaT_PHCL_UMN
vumedi.com/video/ascor-20…
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Ali Arafa retweetledi
Congratulations @aliarafaa on developing the first prognostic blood-based PROTEOMIC biomarker for 177Lu-PSMA-617 efficacy, presented at ASCO ‘25. @UMNCancer @UMNews meetings.asco.org/abstracts-pres…
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@EAntonarakis @DrJustinDrake Incredibly grateful for your mentorship throughout this journey. Huge thanks as well to Dr. Justin Hwang. Building this proteomic assay took a tremendous amount of work, but I’m proud of what we’ve accomplished together. #ASCO25
Emmanuel Antonarakis@EAntonarakis
Congratulations @aliarafaa on developing the first prognostic blood-based PROTEOMIC biomarker for 177Lu-PSMA-617 efficacy, presented at ASCO ‘25. @UMNCancer @UMNews meetings.asco.org/abstracts-pres…
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A huge thank you to @EAntonarakis & Justin Hwang for the mentorship and support. Thank you @TempusAI for making this happen.
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ATM mutated tumors lack TP53 mutations, while gBRCA1-mutated tumors were enriched for TP53, suggesting synthetic essentiality. ATM-dependent cancers rely on intact TP53, opening new therapeutic vulnerabilities. Disrupting TP53 or inhibiting ATM could unlock targeted treatments!🚀
Emmanuel Antonarakis@EAntonarakis
Largest study of BRCA-associated cancers (24,309) shows that somatic tumor landscape is influenced by germline HRR muts: gBRCA1-altered cancers are enriched in somatic TP53 muts; gATM-altered cancers are depleted in TP53 mut. Congrats @aliarafaa @umncancer aacrjournals.org/clincancerres/…
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I am really grateful for my mentors, @EAntonarakis @DrJustinDrake for their support and guidance! A huge thank you to the American Cancer Society @ACS_Research for funding my fellowship! 2025 and 2026 will be great for blood based proteomics!
Emmanuel Antonarakis@EAntonarakis
Congrats @aliarafaa for developing a new method for robust plasma exosome proteomics capable of detecting and quantifying >5000 proteins incl. PSMA, B7H3, TROP2 and STEAP1. A new blood-based biomarker is born! @UMNews mdpi.com/2072-6694/16/2…
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Congrats @aliarafaa for developing a new method for robust plasma exosome proteomics capable of detecting and quantifying >5000 proteins incl. PSMA, B7H3, TROP2 and STEAP1. A new blood-based biomarker is born! @UMNews mdpi.com/2072-6694/16/2…
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Our multi-omics study highlights the unique biology of AMPC, a potential precursor to NEPC, with implications for early therapeutic targeting. FOXA1 and OTX2 may play crucial roles! @DrJustinDrake @EAntonarakis @MPaT_PHCL_UMN @UMNCancer
Emmanuel Antonarakis@EAntonarakis
Amphicrine prostate cancer may be a transitional state between prostate adenoCa and small cell/NEPC. Upregulation of FOXA1 and OTX2 may play a role. Congrats to Megan Ludwig for this deep multi-omic analysis. @UMNCancer @umn_dom @DrJustinDrake @aliarafaa nature.com/articles/s4169…
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Ali Arafa retweetledi
Congratulations to new @AmericanCancer postdoctoral fellow, @aliarafaa. His project addresses an important clinical problem - identifying biomarkers of response to Pluvicto among men receiving treatment for castration resistant metastatic prostate cancer. Thank you and good luck!
Ali Arafa@aliarafaa
I'm thrilled to share that I have been awarded an @AmericanCancer Postdoctoral Fellowship for my prostate cancer research. Many thanks to the prostate cancer team @DrJustinDrake @EAntonarakis @scottdehm and @MPaT_PHCL_UMN for their invaluable support.
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I'm thrilled to share that I have been awarded an @AmericanCancer Postdoctoral Fellowship for my prostate cancer research. Many thanks to the prostate cancer team @DrJustinDrake @EAntonarakis @scottdehm and @MPaT_PHCL_UMN for their invaluable support.
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Ali Arafa retweetledi
Congrats @aliarafaa for delivering your first Oral ASCO Abstract. Your impactful study shows that germline mutations clearly influence somatic mutation landscapes in BRCA-associated cancers. ascopubs.org/doi/abs/10.120…
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Ali Arafa retweetledi
Ali Arafa retweetledi
Abstr 10509: Largest study examining the somatic genomic landscape of tumors developing in germline HRR mutation carriers versus sporadic cancers. Congrats @aliarafaa for your first ASCO Oral presentation. Thanks to @TempusLabs for this rich data set. meetings.asco.org/abstracts-pres…
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Thanks to @EAntonarakis & @DrJustinDrake for their mentorship, guidance, and support. It wouldn't have been possible without your help!
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Humbled to be featured in the March/April edition of Prostatepedia @NASPCC1. I had the opportunity to discuss the impact of the PSMA PET scan on clinical decision-making, current clinical trials, biomarkers, and targeted therapies.
online.flippingbook.com/view/670383721/
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Ali Arafa retweetledi
Effect of germline mutations on somatic alteration landscapes in BRCA-associated cancers [2023] @aliarafaa et al. @EAntonarakis #ASCO23 Abst #10509 meetings.asco.org/abstracts-pres… #PrecisionMedicine #geneticcounselors @UMNews @hopkinskimmel @TempusLabs
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@ggebraelmd @ConquerCancerFd @neerajaiims @ASCO @huntsmancancer @nsayeghmd @eddy_saad @TripNish @vinay_onc @umangtalking @maughanonc @Huntsman_GU @DrDanielHeng @DrChoueiri Congrats, habibi !!!!!! Well deserved
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I am incredibly honored to have received the @ConquerCancerFd Merit Award #ASCO2023!! bit.ly/3GGxoqK
Thanks to the unwavering support of my mentors, colleagues and friends. Thank you @neerajaiims, @ASCO and @huntsmancancer
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