Olga Zhogoleva

and the role of actual exposure to specific grasses in absence of Timothy sensitization (my goal was to explain those rare cases). The thing is, creating a lecture helps you structure your own knowledge and fill in the gaps. I believe it's an amazing part of being a lecturer.

While creating a lecture for physicians on the molecular aspects of grass pollen allergies, I realized I’d missed some important CRD features, like Phl p 5 as a marker of severity, or the variability within group 1 and group 5.

The inflammasome may play a key role in mast cell degranulation and anaphylaxis, although its exact mechanisms remain unclear. A new @AllergyEaaci News & Views article discusses its role in vesicle mobilisation and potential as a therapeutic target. doi.org/10.1111/all.70…

I wanted to name my food allergy book in the same manner, but the editor didn't let me. So now, as a decent grown-up, I am choosing the title for my lecture myself. Who's going to stop me? Ok, Minsk, we'll check your sense of humor in a couple of weeks.

Yesterday I did one thing I have wanted to do for a long time. I named my lecture: "Urticaria: everything you always wanted to know about, but were afraid to ask". It's a reference to Woody Allen, if you know what I mean.

Patients rarely need to interpret medicine. They need to navigate it.

False-Negative Exercise Tests After Wheat Desensitization: What This Study Found 🏃‍♂️🌾 A study of children desensitized to wheat found that 26.4% of those with a negative or indeterminate exercise provocation test (#EPT) still developed exercise‑induced #allergicreactions during follow‑up. 🔍 Key factor: Higher ω5‑gliadin–specific #IgE levels were strongly linked to these false negatives. 🌿 Notable detail: All reactions occurred outdoors, suggesting environmental influences. 📌 Takeaway: Even after a negative EPT, ongoing monitoring is essential for wheat‑desensitized children, and better predictive markers are needed. . 🔗 doi.org/10.1111/pai.70… #pai_journal # ω5gliadin #falsenegatives #exerciseprovocationtest #wheat #predictivemarkers #originalarticle

The Sting Challenge Test (SCT) remains the gold standard to confirm VIT efficacy in Hymenoptera venom allergy. #EAACI Position Paper highlights: ▪️ Confirms real-world protection ▪️ Detects VIT failure ▪️ Not for routine diagnosis Read it here: doi.org/10.1111/all.70…

Misalignment between specialties leads to duplicated tests and conflicting advice

Medicine struggles not with lack of data, but with saying “we don’t know”. I've just finished the lecture for my educational course for physicians about stepping down in CSU, based on collective clinical experience from this absolutely wonderful paper pubmed.ncbi.nlm.nih.gov/36810982/

Overdiagnosis feels helpful, until it blocks better explanations. I'm talking about MCAS. Seems like it has become utterly popular in medical conferences for gastroenterologists and psychiatrists, since a lot of patients are coming from them to allergists lately.

My usual co-host in lectures. Today we've successfully read a lecture on MCAS for physicians together.

We demonstrated that laundry detergents act as adjuvants, promoting airway sensitization and exacerbating allergen-induced asthma. These findings may partly explain the recent increase in allergic diseases. @AllergyEaaci #Allergy #EpithelialBarrier onlinelibrary.wiley.com/doi/10.1111/al…

The International Guideline for the Definition, Classification, Diagnosis and Management of Urticaria 2026 is published onlinelibrary.wiley.com/doi/10.1111/al…

When clinicians don’t understand mechanisms, they replace reasoning with testing.

“Molecular mechanisms are research-only knowledge” is one of the most expensive misconceptions in clinical medicine. Today I read a lecture for physicians about HDM and mold allergies. It's fascinating, how CRD could improve clinical reasoning, when used wisely

MCAS exists. That doesn’t mean it explains most unexplained complaints. This is the main narrative of my upcoming lecture for physicians interested in chronic fatigue syndrome and everything above that.

Very important.

Most diagnostic errors are not caused by lack of knowledge, but by the need to escape uncertainty too early.

Updated my LinkedIn page, took me almost 8 years to do it. Procrastination is my second name. Feel free to follow, btw linkedin.com/in/olga-zhogol…