Looking for a postdoc? Interested in protein evolution and mentorship? Come join our team! hhmi.wd1.myworkdayjobs.com/en-US/External…
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Angela Phillips
16 posts
Angela Phillips retweetledi
Thrilled to announce that I will be joining @MITdeptofBE and @kochinstitute as an Assistant Professor in January 2024! Interested in the intersection of synthetic biology, glycobiology, and immunoengineering? Reimagining #STEMeducation? Join us! 🧬👩🔬 #synbio #glycotime #newPI
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Angela Phillips retweetledi
Pure joy @HHMINEWS #FHScholars IRL with Freeman Hrabowski at our in-person orientation including @KizzyPhD
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Thrilled to start this journey in such vibrant scientific communities @HHMI and @UCSF, and wouldn’t be here without many many mentors, mentees, and collaborators that have influenced my science & mentorship along the way, especially @MattDShoulders and @MichaelMDesai
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So honored to be in the inaugural cohort of #FHScholars – this support from HHMI will enable us to pursue exciting questions in host-virus protein evolution & continue supporting the careers of diverse scientists
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Data also available here for anyone who wants to explore! desai-lab.github.io/wuhan_to_omicr…
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More fun on the sorter with @AliefMoulana @ThomasDupic and Jeffrey Chang! Here we examine the evolutionary pathways of immune escape in SARS-CoV-2 BA.1 & find that these pathways are sometimes short and simple and other times involve several epistatic mutations, check it out!
Alief Moulana@AliefMoulana
Excited to share our work on antibody affinity landscapes of SARS-CoV-2 BA.1--had so much fun working with @ThomasDupic, @angphilli, Jeffrey Chang, @MichaelMDesai, and @jbloom_lab biorxiv.org/content/10.110…
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Excited to share our work on epistasis shaping the evolution of SARS-CoV-2 BA.1 — had a blast working on this with @AliefMoulana @ThomasDupic Jeffrey Chang, @MichaelMDesai & @jbloom_lab: biorxiv.org/content/10.110…
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Thrilled to announce the Phillips lab is opening @UCSF in Sept! We’ll be developing high-throughput methods to examine how molecular properties of viral proteins & antibodies constrain their evolution/coevo. If interested in joining, please reach out! aphillipslab.ucsf.edu/join-us
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@richardneher we're wondering the same thing, working on figuring it out!
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A sequential selection scenario where binding to H1, H3, and B is selected in this order is most effective at generating broad binders. I am wondering to what extent this is a consequence of the mutational space conditional on an observed realization. 6/6
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Very cool evolution/bNAb/#influenza study by Phillips, Lawrence, ... @MichaelMDesai.
They generated ALL combinations (~100k) of somatic mutations of heavy chains of two broadly neutralizing flu ABs and measured their affinity to multiple antigens. 1/6
biorxiv.org/content/10.110…
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Excited to share our preprint on antibody evolution and @_miloj’s awesome data browser: yodabrowser.netlify.app co-led with Katherine Lawrence in @MichaelMDesai’s lab
Michael Desai@MichaelMDesai
New work on binding affinity landscapes of anti-influenza bnAbs, led by Angela Phillips and Katherine Lawrence: biorxiv.org/content/10.110…
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Congrats to all of the new #GilliamFellows, especially @_sheenavasquez and her adviser @Drennan_Lab!
HHMI@hhmi_science
Congratulations to all the #GilliamFellows and their advisers! We have two questions for the Fellows: 1. What do you want to do with your career? 2. How can your adviser help you get there?
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Angela Phillips retweetledi
What do you expect evolution to look like in a microbial population? Check out our new study offering a view of that over 1000 generations in yeast in the lab.
co-led by @alex_nguyen_ba, @jireva, in @MichaelMDesai 's lab nature.com/articles/s4158…
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Honored to have been chosen for the @HHMINEWS #HannaGrayFellows program, which is supporting my work towards understanding evolutionary dynamics in the immune system. Big thanks to my mentors @MichaelMDesai @MattDShoulders @Yu_Shan_Lin @leonidmirny @jbloom_lab @Drennan_Lab
HHMI@hhmi_science
HHMI is excited to announce the selection of 15 exceptional early career scientists as 2019 #HannaGrayFellows to support #diversity in biomedical research: bit.ly/32HTYIX
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