Arthur Price

Today is the #DayOfImmunology 🧬 This year’s theme is all about the #RegulatoryT cell, the immune system’s “guardians of balance”. Read this blog to learn about the Nobel Prize winning discovery by Shimon Sakaguchi, Mary E. Brunkow & Fred Ramsdell - vist.ly/428q5

@Janetbirdope @CRASCRRheum Why ivig ahead of rituximab? Given the potential supply issues, costs and thrombosis risk of high dose ivig, would maintenance rituximab be a better long term option?

Lisa Christopher-Stine Rx of #statin #myositis #IVIg long term #rituximab if needed #triple #Rx Great summary of #pathophysiology #steroids don’t work well alone @CRASCRRheum

Janet Pope sharing her wisdom with Rheumatologists in Pakistan.

1/ Thrilled to share a Perspective that summarizes 30 years of work from the many labs studying the human genetic and immunological causes of infectious diseases: doi.org/10.70962/jhi.2…

Britain’s hospitals average 90% bed occupancy throughout the year, and 95% in winter. This is not normal! 1/3

This post is a crime The content of it is nonsense

Last night in NZ, it is feeling a bit maudlin but looking forward to getting to Glasgow and the lovely weather there. NZ has been a great experience and a beautiful country, just don't trust the roads...

PhD position opening in my lab! Grab your chance to dive into the genetics and pathophysiology of inborn errors of immunity and apply! ⁦@FWOVlaanderen⁩ ⁦@ERC_Research⁩ ⁦@Info4PI⁩ ⁦@KU_Leuven⁩ funded, in an international spirit. kuleuven.be/personeel/jobs…

I finish up in nz in a week (feeling very maudlin) then have a month of touring nz before me return. I'm very worried I'll get bored, please recommend your best recent Immunology papers, I can't fit janeway in my luggage.

@NatDodman One interesting point, as a consultant in nz I'm barely on that, normal pay deals for residents or trainees here would need 5yrs reg experience and 60+hr weeks to hit this. I'm very supportive of RD pay restoration but off see nz pay discussed with quoting their actual pay deals

I am once again reminding @wesstreeting that pay restoration still represents incredible value for money. If he can justify why a. assistant is paid £10k more than a qualified doctor (starting pay £36k) I’ll happily not strike. But that won’t ever happen, because it’s wild.

@AlexRichter3 Awesome, good luck and I shall get my vote in!

So excited to have been shortlisted for this 👇Thank you to whoever nominated me :) It’s a public vote so grateful to all those who vote!

@immunologydoc I missed this one, shall read it over the weekend but looks excellent from the abstract

@aprice1985 cell.com/cell/abstract/… This was also impressive this week

bbc.co.uk/news/articles/… Great story and progress in the world of rare immune deficiency

It's official, I'm coming back to the uk. Sorry for all who thought they were free of me!

@Janetbirdope @RheumNow @eular_org Is if not surprising they got none of the standard care group to remission? I would have thought at least some on MTX and pred without probiotics would make it?

In early #rheumatoid #arthritis do probiotics help? Pts ask & I say dunno 🤷 RCT N=100 on stable #MTX &/or #prednisone Sero+ #RA #probiotics v #PBO added 1 yr remission 63% v 0! Better #HAQ, pain, retention on MTX ⬇️bDMARD ?reproducible Abst#POS0483 @rheumnow @eular_org

@MoarSahitoPTI It shouldn't be. Cetirizine has as good time to onset, better safety profile, available otc, longer duration and evidence of equal efficacy in food allergy.

Why is Diphenhydramine preferred over other antihistamines for short term use in allergies.? 🤔

@Janetbirdope Psoriatic arthritis?

#ClinicalPearl #Diagnosis in 1 #picture pt has lower extremity large@joint synovitis the most likely #diagnosis is…

@RheumNow No doxycyline, I'm shocked!

Using publicly available FAERS safety data, drug-induced photosensitivity (DIP) - among 17+ million safety reports, there 20,236 linked to DIP. The most common wereimmunosuppressants, monoclonal Abs, neoplastic agents, including adalimumab, adapalene, secukinumab, fingolimod buff.ly/qh1Emkw

@LastManStand85 Also important to note this is for an IgA tTG of x10 upper limit of normal, not any degree of positivity. IgG based assays have weaker diagnostic accuracy and generally would still need biopsy confirmation.

Coeliac disease & Rheumatology *TTG (the ab of choice)has a 95% positive predictive value for having Villous atrophy Can also check the Endomysial Antibody 🚩 Note Need to have normal IgA Levels if deficient think about an IgG based test [Prof Sanders] #Rheumatology #MedTwitter

@UKGastroDr @NIHRresearch @ResearchKgh @KettGeneral @UHNNHSGroup That makes sense! I could only make out the headline numbers on my phone! So I guess this tells us fracture is rarely but sometimes the index event in coeliac? Did you look back at those who were diagnosed to see if preceding symptoms?

@aprice1985 @NIHRresearch @ResearchKgh @KettGeneral @UHNNHSGroup Thanks Arthur. If you include those who were known coeliac, prevalence is 0.9%.

Delighted to have a poster for the BRACE-1 study #DDW2025 Screening >1000 adults for coeliac disease. Lots of pride - this simple @NIHRresearch portfolio study set up by @ResearchKgh & exclusively recruited @KettGeneral Was told repeatedly we can’t do it. We did!