Arun K Anguraj Vadivel

My talk #2 will be at the ECR competition on Tuesday at 9:10 am in Frontenac Ballroom. #HUPO2025 I am delighted to be selected as one of the finalists to present my work at the World Congress.

In Harbour room B

Interested in learning the basics of ML/AI models and how to implement them in (prote)omics? I will be hosting a workshop at HUPO2025 @hupo_org on Sunday at 10:15 am at the Westin Harbour Castle Hotel

Thank you ⁦@hupo_org⁩ Human Proteome Organization (HUPO) for the recognition, I will presenting my work at ECR Manuscript plenary session at HUPO2025 hupo.org/News/13519161

A podcast on our recent findings in DMG open.spotify.com/episode/7mk7xT…

The original article: academic.oup.com/neuro-oncology…

Editorial: Commentary on our recent publication on DMG proteome and PTMs. Thank you, Dr. Duchatel and Dr. Nazarian, for your valuable comments and discussion on our findings and field. academic.oup.com/neuro-oncology…

Great learning experience at the Blockchain Conference at the Old Toronto Stock Exchange! ⁦@Futurist_conf⁩ so many talents and promising startups in Canada 🇨🇦

@MattDun17 Thank you! METTL13 is a promising target, not only in DMG but also in pancreatic and lung cancers! It is also over expressed at protein levels across several pediatric brain tumors. Hope someone can help us develop a drug.

Absolutely fantastic paper!

#Proteomics #Methylation #Methylproteome

4. EEF1A1 methylation is linked to poor prognosis, making METTL13 a promising therapeutic target for DMG & other incurable cancers. Fighting DIPG /DMG together—because every child deserves a future.

proteomic landscape of diffuse midline glioma highlights the therapeutic potential of non-histone protein methyltransferases academic.oup.com/neuro-oncology…

@SickKidsNews @CHawkinsLab @OICR_news So happy to see the advancement of our proteomics work to the next stage

Dr. Cynthia Hawkins has been awarded $300K through @OICR_news’ Cancer Therapeutics Innovation Pipeline to improve survival rates of children with brain cancer. Her research aims to develop a new drug or small molecule that can destroy diffuse midline glioma (DMG) cancer cells👇

Hawkins lab @SickKidsNews annual Cell Biology retreat at the Old Mill Toronto 🧬 Thank you to the organizers for a fun and memorable day of learning! It was great seeing all of the incredible work being done at SickKids 🧫🥼🔬

Hence, targeting it should have limited toxicity. Next phase will involve drug discovery after successful completion. #DMG “Unlocking New Hope”

New grant: Happy to receive new grant from OICR to explore a promising therapeutic target identified through methylproteome profiling of diffuse midline glioma. Notably, this target is crucial in cancer cells while sparing normal cells.